| Title: |
Ризик виникнення та профілактика бронхоспазму фізичного навантаження у представників атлетичних видів спорту ; Risk of occurence and prophylaxis of bronchospasm in representatives of athletic kinds of sports |
| Authors: |
Khomyshyn, V. P.; Solomonko, A. O.; Novytskyy, O. O.; Romaniuk, O. B. |
| Source: |
Scientific Messenger of LNU of Veterinary Medicine and Biotechnologies. Series Economical Sciences; Vol 20 No 91 (2018): Scientific Messenger of LNU of Veterinary Medicine and Biotechnologies. Series "Economical Sciences"; 92-96 ; НВ ЛНУ ветеринарної медицини та біотехнологій. Серія "Економічні науки"; Vol 20 No 91 (2018): Scientific Messenger of LNU of Veterinary Medicine and Biotechnologies. Series "Economical Sciences"; 92-96 ; 2519-2701 ; 10.32718/nvlvet91 |
| Publisher Information: |
Stepan Gzhytskyi National University of Veterinary Medicine and Biotechnologies Lviv |
| Publication Year: |
2018 |
| Collection: |
Scientific Messenger of Lviv University of Veterinary Medicine and Biotechnology / Науковий вісник ЛНУ ветеринарної медицини та біотехнологій |
| Description: |
The problem of bronchospasm caused by physical activity is relevant both, in the sport of high achievements and for those who lead an active way of life. The high prevalence of BFL in the sport of high achievements is due to intense physical activity, the influence of climatic factors and the conditions of the training process. However, athletes who regularly do sports and have BFL, experience symptoms of obstruction all the time. Moreover, physical activity can provoke inflammation of the respiratory tract with the synthesis of cysteine leukotrienes, leukocytic infiltration of the mucosa and some other features. Mediators play an important role in the mechanisms of development of BFN. Prostaglandins and leukotrienes (LT) are the main factors that determine both severity and duration of symptoms of asthma. Cisteinil LT contribute to the development of bronchospasm, the greatest biological activity is characterized by LT C4, which is further transformed into a metabolite of LT E4 through the LT D4. A number of studies have found that the presence of clinical symptoms of difficult breathing, according to the results of the survey, is not a reliable indicator of BFN and requires objective confirmation in the form of an examination of the function of external respiration after exercise. It is known that athletes actively training with PFN there is a significant increase in the excretion of LT E4 and 9α, 11β-prostaglandin F2 in the urine, as well as the indicators of LT C4 and B4 in blood plasma after intense physical activity. In addition, physical activity has a powerful stimulating effect on cysteine luteum production, enhancing the expression of genes encoding the 5-lipoxygenase transformation pathway of arachidonic acid. 30% athletes of athletic sport show BFL availability. The exercise test should be conducted under certain conditions. During the test, a high level of ventilation of the lungs should be maintained. The use of load testing to detect bronchoconstriction induced by FN has a high predictive value. ... |
| Document Type: |
article in journal/newspaper |
| File Description: |
application/pdf |
| Language: |
Ukrainian |
| Relation: |
https://nvlvet.com.ua/index.php/economy/article/view/2499/2483; https://nvlvet.com.ua/index.php/economy/article/view/2499 |
| DOI: |
10.32718/nvlvet9119 |
| Availability: |
https://nvlvet.com.ua/index.php/economy/article/view/2499; https://doi.org/10.32718/nvlvet9119 |
| Rights: |
Copyright (c) 2018 Scientific Messenger of LNU of Veterinary Medicine and Biotechnologies ; https://creativecommons.org/licenses/by/4.0 |
| Accession Number: |
edsbas.B2CDAC97 |
| Database: |
BASE |