| Title: |
Pelvic magnetic resonance imaging in the ewe: a model for experimental gynecologic research. |
| Authors: |
Gauthier, Tristan; Marquet, Pierre; Kanoun, Dorra; Maubon, Antoine; Piver, Pascal; Couquet, Claude; Aubard, Yves |
| Contributors: |
Institut Gustave Roussy (IGR); Université Paris-Sud - Paris 11 (UP11); Pharmacologie des Immunosuppresseurs et de la Transplantation (PIST); Université de Limoges (UNILIM)-CHU Limoges-Génomique, Environnement, Immunité, Santé, Thérapeutique (GEIST FR CNRS 3503)-Institut National de la Santé et de la Recherche Médicale (INSERM); Service de Pharmacologie, toxicologie et pharmacovigilance CHU Limoges; CHU Limoges; Service Pharmacologie Clinique CHU Toulouse; Pôle Santé publique et médecine publique CHU Toulouse; Centre Hospitalier Universitaire de Toulouse (CHU Toulouse)-Centre Hospitalier Universitaire de Toulouse (CHU Toulouse); Service de Radiologie et Imagerie Médicale CHU Limoges; Université de Limoges (UNILIM) |
| Source: |
ISSN: 1341-8076. |
| Publisher Information: |
CCSD; Wiley |
| Publication Year: |
2014 |
| Subject Terms: |
MESH: Animals; Inbred Strains; MESH: Sheep; Domestic; MESH: Uterus; MESH: Contrast Media; MESH: Feasibility Studies; MESH: Female; MESH: France; MESH: Gadolinium; MESH: Injections; Intravenous; MESH: Magnetic Resonance Imaging; MESH: Ovary; [SDV.SP]Life Sciences [q-bio]/Pharmaceutical sciences |
| Description: |
International audience ; AIM: Our goal was to demonstrate the feasibility of pelvic magnetic resonance imaging (MRI) in the ewe. MATERIAL AND METHODS: Two ewes underwent a pelvic 3 Tesla MRI scan, under light anesthesia, with T2-weighted fast spin-echo images and T1-weighted spoiled gradient-echo images. Multiplan T1 weighted images were also obtained after the intravenous injection of a contrast product. One ewe was anestrous and the other one had undergone ovarian stimulation. RESULTS: No incident occurred during the examination. Both the uterus (with two horns) and the ovaries were identified. The intensity of the endometrial, myometrial and ovarian signals was similar to that encountered in women. The uterus and ovaries could be enhanced in both cases. Pelvic vasculature was also studied. In the case of hormonal stimulation, the endometrium was thicker, follicular growth was identified and enhancement seemed greater. CONCLUSION: MRI in the ewe is feasible and could be helpful in experimental gynecologic research, especially in uterus transplantation. |
| Document Type: |
article in journal/newspaper |
| Language: |
English |
| Relation: |
info:eu-repo/semantics/altIdentifier/pmid/24033802; PUBMED: 24033802 |
| DOI: |
10.1111/jog.12141 |
| Availability: |
https://inserm.hal.science/inserm-00925117; https://doi.org/10.1111/jog.12141 |
| Accession Number: |
edsbas.B30D3237 |
| Database: |
BASE |