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Evaluation of MALDI Biotyper Interpretation Criteria for Accurate Identification of Nontuberculous Mycobacteria

Title: Evaluation of MALDI Biotyper Interpretation Criteria for Accurate Identification of Nontuberculous Mycobacteria
Authors: Rodriguez-Temporal, David; Rodríguez-Sánchez, Belén; Alcaide, Fernando
Contributors: Land, Geoffrey A.; MEC | Instituto de Salud Carlos III
Source: Journal of Clinical Microbiology ; volume 58, issue 10 ; ISSN 0095-1137 1098-660X
Publisher Information: American Society for Microbiology
Publication Year: 2020
Description: Identification of mycobacteria by matrix-assisted laser desorption ionization–time of flight mass spectrometry (MALDI-TOF MS) requires not only a good protein extraction protocol but also an adequate cutoff score in order to provide reliable results. The aim of this study was to assess the cutoff scores proposed by the MALDI-TOF MS system for mycobacterial identification. A total of 693 clinical isolates from a liquid medium and 760 from a solid medium were analyzed, encompassing 67 different species of nontuberculous mycobacteria (NTM).
Document Type: article in journal/newspaper
Language: English
DOI: 10.1128/jcm.01103-20
DOI: 10.1128/JCM.01103-20
Availability: https://doi.org/10.1128/jcm.01103-20; https://journals.asm.org/doi/pdf/10.1128/JCM.01103-20
Rights: https://journals.asm.org/non-commercial-tdm-license
Accession Number: edsbas.B3261F61
Database: BASE