| Title: |
More than an Amide Bioisostere: Discovery of 1,2,4-Triazole-containing Pyrazolo[1,5- a ]pyrimidine Host CSNK2 Inhibitors for Combatting β-Coronavirus Replication |
| Authors: |
Ong, Han Wee; Yang, Xuan; Smith, Jeffery L.; Dickmander, Rebekah J.; Brown, Jason W.; Havener, Tammy M.; Taft-Benz, Sharon; Howell, Stefanie; Sanders, Marcia K.; Capener, Jacob L.; Couñago, Rafael M.; Chang, Edcon; Krämer, Andreas; Moorman, Nathaniel J.; Heise, Mark; Axtman, Alison D.; Drewry, David H.; Willson, Timothy M. |
| Contributors: |
North Carolina General Assembly; Takeda Pharmaceutical Company; University of North Carolina; North Carolina Biotechnology Center; U.S. Department of Defense; NIH Illuminating the Druggable Genome; National Institutes of Health |
| Source: |
Journal of Medicinal Chemistry ; volume 67, issue 14, page 12261-12313 ; ISSN 0022-2623 1520-4804 |
| Publisher Information: |
American Chemical Society (ACS) |
| Publication Year: |
2024 |
| Document Type: |
article in journal/newspaper |
| Language: |
English |
| DOI: |
10.1021/acs.jmedchem.4c00962 |
| Availability: |
https://doi.org/10.1021/acs.jmedchem.4c00962; https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.4c00962 |
| Rights: |
https://creativecommons.org/licenses/by-nc-nd/4.0/ |
| Accession Number: |
edsbas.B3F2CD48 |
| Database: |
BASE |