| Title: |
Lupus myelopathy |
| Authors: |
Raciborska, Dominika D; Noyce, Alastair John; Pyne, Dev; Turner, Benjamin P |
| Source: |
Practical Neurology ; volume 18, issue 1, page 66-69 ; ISSN 1474-7758 1474-7766 |
| Publisher Information: |
BMJ |
| Publication Year: |
2017 |
| Description: |
Although neurological manifestations of systemic lupus erythematosus (SLE) are well recognised, myelopathy complicating SLE is rare. A 35-year-old woman presented with non-specific symptoms and a respiratory tract infection but had serological evidence of SLE. She subsequently deteriorated rapidly, developing a catastrophic spinal cord syndrome. Her initial MRI was normal; but after 1 month, her encephalopathy having progressed, repeat imaging showed characteristic myelitic changes. She responded only slowly to a combination of cyclophosphamide and corticosteroids. This case exemplifies the mixed presentations of SLE, including the under-recognised ‘subpial leukomyelopathy’ of central nervous system lupus. It highlights the challenges in managing lupus-related myelopathy and the benefits of a multidisciplinary approach to care. |
| Document Type: |
article in journal/newspaper |
| Language: |
English |
| DOI: |
10.1136/practneurol-2017-001756 |
| Availability: |
https://doi.org/10.1136/practneurol-2017-001756; https://syndication.highwire.org/content/doi/10.1136/practneurol-2017-001756 |
| Accession Number: |
edsbas.B48FE9ED |
| Database: |
BASE |