| Title: |
Population Genomics of Incipient Allochronic Divergence in the Pine Processionary Moth |
| Authors: |
Muller, Tanguy; Gautier, Mathieu; Lombaert, Eric; Leblois, Raphaël; Sauné, Laure; Branco, Manuela; Kerdelhué, Carole; Perrier, Charles |
| Contributors: |
Centre de Biologie pour la Gestion des Populations (UMR CBGP); Centre de Coopération Internationale en Recherche Agronomique pour le Développement (Cirad)-Institut de Recherche pour le Développement (IRD Occitanie )-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Institut Agro Montpellier; Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Université de Montpellier (UM); Institut Sophia Agrobiotech (ISA); Université Nice Sophia Antipolis (1965 - 2019) (UNS)-Centre National de la Recherche Scientifique (CNRS)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Université Côte d'Azur (UniCA); Forest Research Centre Lisbon; School of Agriculture Lisboa; Universidade de Lisboa = University of Lisbon = Université de Lisbonne Lisboa (ULISBOA)-Universidade de Lisboa = University of Lisbon = Université de Lisbonne Lisboa (ULISBOA); The authors wish to thank the ANR for a collaborative grant (LOADEXP; ANR-22-CE02-0009) to C.P. which covered half of sequencing costs and half of a PhD scholarship to T.M.; funding from INRAE to C.P. covering half of the sequencing costs and half of a PhD scholarship; the MGX-GENOMICS platform for sequencing; Bioinfo Genotoul https://doi.org/10.15454/1.5572369328961167E12 for computing facilities. R.L. and C.P. were partly supported by the Occitanie Regional Council's Program “Key Challenge BiodivOc” (DevOCGen project and GambOc project, respectively).; ANR-22-CE02-0009,LOADEXP,Génomique du fardeau mutationnel au cours des expansions(2022) |
| Source: |
ISSN: 0962-1083. |
| Publisher Information: |
CCSD; Wiley |
| Publication Year: |
2025 |
| Collection: |
Université de Montpellier: HAL |
| Subject Terms: |
inbreeding; allochrony; circadian genes; demographic history; genetic load; [SDV.GEN.GPO]Life Sciences [q-bio]/Genetics/Populations and Evolution [q-bio.PE]; [INFO.INFO-MO]Computer Science [cs]/Modeling and Simulation; [SDV.BA.ZI]Life Sciences [q-bio]/Animal biology/Invertebrate Zoology; [SDV.BBM.GTP]Life Sciences [q-bio]/Biochemistry; Molecular Biology/Genomics [q-bio.GN]; [SDV.BID.EVO]Life Sciences [q-bio]/Biodiversity/Populations and Evolution [q-bio.PE] |
| Description: |
Data Availability Statement: All raw data (fastq files for Pool-Seq and Ind-Seq data) will be available in the SRA repository BioProject: PRJNA1269716 (publicly available upon paper publication). Scripts will be available at https://github.com/TanguyMuller/Genomic_of_Allochrony. ; International audience ; Allochronic divergence is a key evolutionary mechanism that can frequently lead to incipient speciation. Although theoretical models suggest that such divergence is notably facilitated by small population size and genetic polymorphisms influencing reproductive timing, though constrained by genetic load, empirical validation remains limited. We investigated these predictions by re-analysing a case of allochronic differentiation between two sympatric populations of pine processionary moth (Thaumetopoea pityocampa) in Portugal, using whole genome resequencing (IndSeq and PoolSeq) of those two populations and eight allopatric ones. We inferred the demographic history of those populations, assessed their genetic load and searched for genomic regions associated with life cycle differences. Our analyses revealed a recent split between the sympatric allochronic populations, accompanied by a strong reduction in gene flow, bottlenecks, inbreeding and accumulation of deleterious variants. Genome scans identified several loci associated with life cycle variation, including genes putatively involved in circadian rhythm regulation, predominantly located on the Z chromosome. We discuss how these empirical genomic findings support theoretical expectations that assortative mating driven by differences in reproductive timing, underpinned by polymorphisms in circadian genes, along with genetic drift and purge of genetic load at high-impact sites, can promote the onset and persistence of allochronic divergence. |
| Document Type: |
article in journal/newspaper |
| Language: |
English |
| Relation: |
info:eu-repo/semantics/altIdentifier/pmid/41312817; BIORXIV: 2025.06.09.657100; PUBMED: 41312817; WOS: 001626027000001 |
| DOI: |
10.1111/mec.70189 |
| Availability: |
https://hal.inrae.fr/hal-05390855; https://hal.inrae.fr/hal-05390855v1/document; https://hal.inrae.fr/hal-05390855v1/file/mec.70189.pdf; https://doi.org/10.1111/mec.70189 |
| Rights: |
https://creativecommons.org/licenses/by-nc/4.0/ ; info:eu-repo/semantics/OpenAccess |
| Accession Number: |
edsbas.B5CF22D0 |
| Database: |
BASE |