| Title: |
Differences in disease characteristics and outcomes as determined by biological sex in a large UK idiopathic pulmonary fibrosis population: Analysis from the British Thoracic Society, Interstitial Lung Disease registry data |
| Authors: |
Mulholland, Sarah; Dixon, Giles; Wells, Matthew; White, Paul; Harding, Sam; Russell, Anne-Marie; Barratt, Shaney L |
| Publisher Information: |
BMJ Publishing Group |
| Publication Year: |
2025 |
| Collection: |
University of the West of England, Bristol: UWE Research Repository |
| Description: |
Growing evidence suggests that biological sex influences the incidence, presentation, diagnosis and outcomes of many lung diseases. Understanding these differences is the first step towards precision medicine to improve patient care. In this cross-sectional study, idiopathic pulmonary fibrosis (IPF) patients enrolled in a national (UK), multicentre registry were categorised by sex and analysed for differences in demographics, pulmonary function tests, high resolution CT radiological pattern, eligibility/uptake of antifibrotics and survival. Of 7177 cases, 77.8% (n=5587) were male, median age 75 years (IQR 69.5–80.5) for both sexes (p=0.83). Males were more likely to have a history of smoking (males 72.9% vs females 60.5%, p |
| Document Type: |
article in journal/newspaper |
| Language: |
English |
| Relation: |
https://uwe-repository.worktribe.com/file/14795225/1/Differences%20in%20disease%20characteristics%20and%20outcomes%20as%20determined%20by%20biological%20sex%20in%20a%20large%20UK%20idiopathic%20pulmonary%20fibrosis%20population%3A%20analysis%20from%20the%20British%20Thoracic%20Society,%20Interstitial%20Lung%20Disease%20registry%20data; https://uwe-repository.worktribe.com/output/14795225 |
| Availability: |
https://uwe-repository.worktribe.com/output/14795225 |
| Rights: |
openAccess ; http://creativecommons.org/licenses/by/4.0/ |
| Accession Number: |
edsbas.B5F9AF0 |
| Database: |
BASE |