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Antibiotic Prophylaxis in Dermatologic Surgery: Advisory Statement 2025 (APDSAS 2025)

Title: Antibiotic Prophylaxis in Dermatologic Surgery: Advisory Statement 2025 (APDSAS 2025)
Authors: Campbell, Elliott; Virk, Abinash; Lessard, Sarah; Lohman, Mary E.; Otley, Clark
Source: Dermatologic Surgery ; ISSN 1076-0512 1524-4725
Publisher Information: Ovid Technologies (Wolters Kluwer Health)
Publication Year: 2026
Description: BACKGROUND Guidelines and evidence related to antibiotic prophylaxis in dermatologic surgery have evolved since the authors' previously published advisory statement. OBJECTIVE To provide an updated advisory statement on antibiotic prophylaxis in dermatologic surgery as guided by updated recommendations from the American Heart Association and the American Dental Association with the American Academy of Orthopaedic Surgeons guidelines. METHODS A structured literature review was performed. A multidisciplinary team of specialists from dermatologic surgery, infectious diseases, and pharmacy were convened to review up-to-date data and develop updated comprehensive evidence-based recommendations. RESULTS Consistent with the previous advisory statement, prophylactic antibiotics are recommended for patients with high-risk cardiac or prosthetic joint conditions, when the dermatologic surgical site is infected or if the procedure breaches the mucosa. Significant changes were made for prophylaxis of surgical site infection. Updated recommendations were made regarding antibiotic selection in penicillin-allergic patients and intraoperative use of intraincisional clindamycin in the local anesthetic. LIMITATIONS Reviewed data are predominantly limited to retrospective data. CONCLUSION Recommendations regarding antibiotic prophylaxis around dermatologic surgery are evolving as new data and practices are introduced. The 2025 advisory statement provides the latest recommendations for appropriate use of antibiotic prophylaxis in dermatologic surgery.
Document Type: article in journal/newspaper
Language: English
DOI: 10.1097/dss.0000000000005056
DOI: 10.1097/DSS.0000000000005056
Availability: https://doi.org/10.1097/dss.0000000000005056; https://journals.lww.com/10.1097/DSS.0000000000005056
Accession Number: edsbas.B64F0474
Database: BASE