| Title: |
An exploratory study on counterfactual thinking in amyotrophic lateral sclerosis |
| Authors: |
Poletti B.; Aiello E. N.; Tagini S.; Solca F.; Torre S.; Colombo E.; Maranzano A.; Bonetti R.; Schevegher F.; Morelli C.; Doretti A.; Verde F.; Barbieri S.; Mameli F.; Priori A.; Ferrucci R.; Silani V.; Cherubini P.; Pravettoni G.; Ticozzi N. |
| Contributors: |
Poletti, B; Aiello, E; Tagini, S; Solca, F; Torre, S; Colombo, E; Maranzano, A; Bonetti, R; Schevegher, F; Morelli, C; Doretti, A; Verde, F; Barbieri, S; Mameli, F; Priori, A; Ferrucci, R; Silani, V; Cherubini, P; Pravettoni, G; Ticozzi, N |
| Publisher Information: |
Frontiers Media SA; CH |
| Publication Year: |
2023 |
| Collection: |
Università degli Studi di Milano-Bicocca: BOA (Bicocca Open Archive) |
| Subject Terms: |
amyotrophic lateral sclerosi; cognition; counterfactual thinking; dementia; frontotemporal degeneration; neuropsychology |
| Description: |
Objectives: This study aimed at exploring (1) the motor and non-motor correlates of counterfactual thinking (CFT) abilities in non-demented amyotrophic lateral sclerosis (ALS) patients and (2) the ability of CFT measures to discriminate these patients from healthy controls (HCs) and patients with and without cognitive impairment. Methods: N = 110 ALS patients and N = 51 HCs were administered two CFT tasks, whose sum, resulting in a CFT Index (CFTI), was addressed as the outcome. Patients further underwent an in-depth cognitive, behavioral, and motor-functional evaluation. Correlational analyses were run to explore the correlates of the CFTI in patients. Logistic regressions were performed to test whether the CFTI could discriminate patients from HCs. Results: The CFTI was selectively associated (p ≤ 0.005) with fluency and memory subscales of the Edinburgh Cognitive and Behavioral ALS Screen (ECAS), but not with other variables. CFTI scores discriminated patients from HCs (p < 0.001) with high accuracy (82%), but not patients with a normal vs. defective performance on the ECAS-Total. Conclusion: CFT measures in non-demented ALS patients were associated with verbal fluency and memory functions, and they were also able to discriminate them from HCs. |
| Document Type: |
article in journal/newspaper |
| File Description: |
ELETTRONICO |
| Language: |
English |
| Relation: |
info:eu-repo/semantics/altIdentifier/wos/WOS:001130051500001; volume:14; journal:FRONTIERS IN PSYCHOLOGY; https://hdl.handle.net/10281/520826 |
| DOI: |
10.3389/fpsyg.2023.1281976 |
| Availability: |
https://hdl.handle.net/10281/520826; https://doi.org/10.3389/fpsyg.2023.1281976 |
| Rights: |
info:eu-repo/semantics/openAccess ; license:Creative Commons ; license uri:http://creativecommons.org/licenses/by/4.0/ |
| Accession Number: |
edsbas.B791C623 |
| Database: |
BASE |