| Title: |
P0329 Clostridium difficile infection associates with the need for biologics: a retrospective long-term analysis in a cohort of 102 ibd patients |
| Authors: |
Spagnuolo, R; Scarlata, G G M; Morano, D; Imoletti, F; Suraci, E; Marasco, R; Imeneo, M G; Pavia, G; Pantanella, M; Calabretta, M V; Marascio, N; Quirino, A; Trecarichi, E M; Russo, A; Abenavoli, L; Matera, G; Luzza, F |
| Source: |
Journal of Crohn's and Colitis ; volume 19, issue Supplement_1, page i791-i791 ; ISSN 1873-9946 1876-4479 |
| Publisher Information: |
Oxford University Press (OUP) |
| Publication Year: |
2025 |
| Description: |
Background Gastrointestinal Infections (GIs) pose a significant challenge in patients with inflammatory bowel diseases (IBD), complicating its management and triggering IBD relapses. The overlap in clinical symptoms makes complex differentiating GIs from IBD flares, impacting therapeutic decisions. This study aims at evaluating the long-term impact of GIs in IBD patients. Methods From January 2020 to September 2024, 102 IBD patients (mean age 45±16 yrs; 78 ulcerative colitis, UC and 24 Crohn’s disease, CD) experiencing a clinical relapse according to ECCO guidelines, were retrospectively evaluated. GIs were established via stool immunochromatography and multiplex molecular assay. Demographic, clinical and laboratory findings along with the treatment were noticed at the time of flare, 6 and 12 months later. Statistical analysis was performed by Mann-Witney and chi-square test as appropriate (p |
| Document Type: |
article in journal/newspaper |
| Language: |
English |
| DOI: |
10.1093/ecco-jcc/jjae190.0503 |
| Availability: |
https://doi.org/10.1093/ecco-jcc/jjae190.0503; https://academic.oup.com/ecco-jcc/article-pdf/19/Supplement_1/i791/61543220/jjae190.0503.pdf |
| Rights: |
https://academic.oup.com/pages/standard-publication-reuse-rights |
| Accession Number: |
edsbas.B823233F |
| Database: |
BASE |