| Title: |
Impact of green tea on the deleterious cardiometabolic effects of 7-days unhealthy lifestyle in young healthy males. |
| Authors: |
Roberts, KA; Draijer, R; Hopkins, ND; de Graaf, Y; Holder, SM; Carter, SE; Thijssen, DHJ; Low, DA |
| Publisher Information: |
Wiley Open Access |
| Publication Year: |
2021 |
| Collection: |
Liverpool John Moores University: LJMU Research Online |
| Subject Terms: |
TX341 Nutrition. Foods and food supply; QH301 Biology; QP Physiology; RA0421 Public health. Hygiene. Preventive Medicine; RC1200 Sports Medicine |
| Description: |
PURPOSE: The aim of this study was to examine if catechin-rich green tea abrogates the negative effects of 7-days of physical inactivity and excessive calorie-intake on insulin homeostasis and peripheral vascular function. METHODS: Using a randomized, double-blind, crossover design, twelve healthy men (29 ± 6 yrs) underwent 7-days unhealthy lifestyle (UL), including physical inactivity (-50% steps/day) and overfeeding (+50% kcal/day). This was combined with green tea consumption (UL-tea; 3 doses/day) or placebo (UL-placebo). Before and after each intervention, we examined postprandial blood glucose and insulin (3-h after a 1,202 kcal meal) and upper and lower limb vascular function (flow-mediated dilation (FMD%)) and carotid artery reactivity (CAR%). RESULTS: UL-placebo increased postprandial glucose and insulin, while UL-tea decreased postprandial glucose and insulin (Time*Intervention interaction effects: both p < 0.05). UL-placebo decreased CAR% and femoral FMD%, while UL-tea prevented these effects (Time*Intervention interaction effects of p < 0.04 and p < 0.001, respectively). There was no main effect of Time or Time*Intervention interaction (both p > 0.05) for brachial FMD%. CONCLUSION: Seven days of physical inactivity and overfeeding impair insulin homeostasis and vascular function. These effects were mitigated by a daily intake of catechin-rich green tea. |
| Document Type: |
article in journal/newspaper |
| File Description: |
text |
| Language: |
English |
| ISSN: |
2051-817X |
| Relation: |
https://researchonline.ljmu.ac.uk/id/eprint/14605/1/phy2.14720.pdf; Roberts, KA, Draijer, R, Hopkins, ND, de Graaf, Y, Holder, SM, Carter, SE, Thijssen, DHJ and Low, DA (2021) Impact of green tea on the deleterious cardiometabolic effects of 7-days unhealthy lifestyle in young healthy males. Physiological Reports, 9 (5). ISSN 2051-817X |
| DOI: |
10.14814/phy2.14720 |
| Availability: |
https://researchonline.ljmu.ac.uk/id/eprint/14605/; https://researchonline.ljmu.ac.uk/id/eprint/14605/1/phy2.14720.pdf; https://doi.org/10.14814/phy2.14720 |
| Rights: |
cc_by |
| Accession Number: |
edsbas.B86AB6C5 |
| Database: |
BASE |