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In vitro and in vivo effects of 2,4 diaminoquinazoline inhibitors of the decapping scavenger enzyme DcpS: Context-specific modulation of SMN transcript levels

Title: In vitro and in vivo effects of 2,4 diaminoquinazoline inhibitors of the decapping scavenger enzyme DcpS: Context-specific modulation of SMN transcript levels
Authors: Cherry, Jonathan J.; DiDonato, Christine J.; Androphy, Elliot J.; Calo, Alessandro; Potter, Kyle; Custer, Sara K.; Du, Sarah; Foley, Timothy L.; Gopalsamy, Ariamala; Reedich, Emily J.; Gordo, Susana M.; Gordon, William; Hosea, Natalie; Jones, Lyn H.; Krizay, Daniel K.; LaRosa, Gregory; Li, Hongxia; Mathur, Sachin; Menard, Carol A.; Patel, Paraj; Ramos-Zayas, Rebeca; Rietz, Anne; Rong, Haojing; Zhang, Baohong; Tones, Michael A.
Contributors: Blum, Robert; Pfizer; National Institute of Neurological Disorders and Stroke; Muscular Dystrophy Association; Cure SMA; Anne & Robert H. Lurie Children's Hospital of Chicago Foundation
Source: PLOS ONE ; volume 12, issue 9, page e0185079 ; ISSN 1932-6203
Publisher Information: Public Library of Science (PLoS)
Publication Year: 2017
Collection: PLOS Publications (via CrossRef)
Document Type: article in journal/newspaper
Language: English
DOI: 10.1371/journal.pone.0185079
Availability: https://doi.org/10.1371/journal.pone.0185079; http://dx.plos.org/10.1371/journal.pone.0185079
Rights: http://creativecommons.org/licenses/by/4.0/
Accession Number: edsbas.B8775111
Database: BASE