| Title: |
Incidence, diagnosis, management and outcome of acute mesenteric ischaemia: a prospective, multicentre observational study (AMESI Study) |
| Authors: |
Reintam Blaser, Annika; Koitmäe, Merli; Bjorck, Martin; Acosta, Stefan; Bala, Miklosh; Bodnar, Zsolt; Casian, Dumitru; Demetrashvili, Zaza; D'Oria, Mario; Durán Muñoz-Cruzado, Virginia María; Forbes, Alastair; Fuglseth, Hanne; hellerman, moran; Hess, Benjamin; Kase, Karri; Kirov, Mikhail; Lein, Kristoffer; Lindner, Matthias; Loudet, Cecilia Inés; Mole, Damian; Murruste, Marko; Nuzzo, Alexandre; Saar, Sten; scheiterle, maximilian; Starkopf, Joel; Talving, Peep; Voomets, Anna-Liisa; Voon, Kenneth; Yunus, Mohammad Alif; Tamme, Kadri; AMESI Investigators (Collaborators); Corcos, Olivier; Castier, Yves; Ronot, Maxime; Biloslavo, Alan; Paiano, Lucia; Elke, Gunnar; Nagel, Denise; Radke, David I.; Vilca Becerra, Jacqueline; Abeleyra, María Elina; Cahenzli, Martin; Semenkova, Tatjana; Nikonov, Anton; Smetkin, Alexey; Nedredal, Geir Ivar; Irtun, Øivind; Cohen-Arazi, Oded; Keda, Asaf; Rojnoveanu, Gheorghe; Ursu, Alexandr; Ciuró, Felipe Pareja; García-Leon, Anabel; García-Sánchez, Carlos Javier; Hui, Lim Jia; Ling, Loy Yuan; Kagan, Ilya; Singer, Pierre; Lipping, Edgar; Tvaladze, Ana; Damaskos, Dimitrios; Clinch, Darja; Qing, Too Xiao; Vetrhus, Morten; Martellucci, Jacopo; Cerino, Giulia; Hong, Donghuang; Liu, Jinsheng; Ong, Ernest; Kundogan, Kursat; Talih, Tutkun; Bains, Lovenish; Visconti, Diego; Gibello, Lorenzo; Jailani, Ruhi Fadzlyana; Ashra, Muhammad Amirul; Dzulkarnaen Zakaria, Andee; Najmuddin Mohd Ghazi, Ahmad Faiz; Abd Ghani, Nur Suriyana; Ab Rahim, Mohd Fadliyazid; Augustin, Goran; Halužan, Damir; Gurjar, Mohan; Rahul, Rahul; Hayati, Firdaus; Mah, Jin-Jiun |
| Source: |
http://lobid.org/resources/99370670818906441#!, 28(1):32. |
| Publication Year: |
2024 |
| Collection: |
Publisso (ZB MED-Publikationsportal Lebenswissenschaften) |
| Subject Terms: |
Outcome; Hospitalization [MeSH]; Adult [MeSH]; Humans [MeSH]; Prospective Studies [MeSH]; Incidence [MeSH]; Hospitals [MeSH]; Mesenteric ischaemia; Epidemiology; Mesenteric Ischemia [MeSH]; Research; Diagnosis; Management |
| Description: |
Abstract Background The aim of this multicentre prospective observational study was to identify the incidence, patient characteristics, diagnostic pathway, management and outcome of acute mesenteric ischaemia (AMI). Methods All adult patients with clinical suspicion of AMI admitted or transferred to 32 participating hospitals from 06.06.2022 to 05.04.2023 were included. Participants who were subsequently shown not to have AMI or had localized intestinal gangrene due to strangulating bowel obstruction had only baseline and outcome data collected. Results AMI occurred in 0.038% of adult admissions in participating acute care hospitals worldwide. From a total of 705 included patients, 418 patients had confirmed AMI. In 69% AMI was the primary reason for admission, while in 31% AMI occurred after having been admitted with another diagnosis. Median time from onset of symptoms to hospital admission in patients admitted due to AMI was 24 h (interquartile range 9-48h) and time from admission to diagnosis was 6h (1–12 h). Occlusive arterial AMI was diagnosed in 231 (55.3%), venous in 73 (17.5%), non-occlusive (NOMI) in 55 (13.2%), other type in 11 (2.6%) and the subtype could not be classified in 48 (11.5%) patients. Surgery was the initial management in 242 (58%) patients, of which 59 (24.4%) underwent revascularization. Endovascular revascularization alone was carried out in 54 (13%), conservative treatment in 76 (18%) and palliative care in 46 (11%) patients. From patients with occlusive arterial AMI, revascularization was undertaken in 104 (45%), with 40 (38%) of them in one site admitting selected patients. Overall in-hospital and 90-day mortality of AMI was 49% and 53.3%, respectively, and among subtypes was lowest ... |
| Document Type: |
article in journal/newspaper |
| Language: |
English |
| ISBN: |
978-9937-0-6708-9; 9937-0-6708-1 |
| Relation: |
https://repository.publisso.de/resource/frl:6504321; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10807222/ |
| DOI: |
10.1186/s13054-024-04807-4 |
| Availability: |
https://repository.publisso.de/resource/frl:6504321; https://doi.org/10.1186/s13054-024-04807-4; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10807222/ |
| Rights: |
https://creativecommons.org/licenses/by/4.0/ |
| Accession Number: |
edsbas.B8884D5E |
| Database: |
BASE |