| Title: |
O005 Age related changes in sleep quantitative EEG and longitudinal relationship to cognitive function |
| Authors: |
Stumbles, E; Appleton, S; Adams, R; Yee, B; Parker, J; Vakulin, A; Wittert, G; Marshall, N; D’Rozario, A |
| Source: |
Sleep Advances ; volume 5, issue Supplement_1, page A3-A3 ; ISSN 2632-5012 |
| Publisher Information: |
Oxford University Press (OUP) |
| Publication Year: |
2024 |
| Description: |
Objectives Altered sleep microarchitecture including sleep spindles and decline in cognitive function occurs with advancing age. However, the longitudinal relationship between changes in sleep neurophysiology and cognition in middle-to-late life is currently unclear. This study examined sleep micro-architecture measured by electroencephalography (EEG) and cognitive performance in middle-aged and older men over a 10-year period. Methods 156 participants from the Florey Adelaide Male Ageing Study who reported no previous obstructive sleep apnoea diagnosis underwent home-based polysomnography and cognitive testing including mini mental state examination (MMSE) and trail-making tests A (visual attention) and B (executive function) at baseline (2010-2011) and follow up (2019-2020). Power spectral analysis of single-channel EEG (F4-M1) recordings at follow up (n=142) was performed. Baseline and follow-up sleep parameters including spindle metrics, and cognition were compared using paired t-tests, and associations examined with Pearson’s correlations. Results NREM (267.6 vs 299.2 minutes) and REM (57.0 vs 77.7 minutes) sleep was higher during follow up compared to baseline (p |
| Document Type: |
article in journal/newspaper |
| Language: |
English |
| DOI: |
10.1093/sleepadvances/zpae070.005 |
| Availability: |
https://doi.org/10.1093/sleepadvances/zpae070.005; https://academic.oup.com/sleepadvances/article-pdf/5/Supplement_1/A3/60938717/zpae070.005.pdf |
| Rights: |
https://creativecommons.org/licenses/by-nc-nd/4.0/ |
| Accession Number: |
edsbas.B9804F38 |
| Database: |
BASE |