| Title: |
Natural history and outcomes in paediatric RASopathy-associated hypertrophic cardiomyopathy |
| Authors: |
Boleti, Olga; Norrish, Gabrielle; Field, Ella; Dady, Kathleen; Summers, Kim; Nepali, Gauri; Bhole, Vinay; Uzun, Orhan; Wong, Amos; Daubeney, Piers EF; Stuart, Graham; Fernandes, Precylia; Mcleod, Karen; Ilina, Maria; Ali, Muhammad Najih Liaqath; Bharucha, Tara; Donne, Grazia Delle; Brown, Elspeth; Linter, Katie; Jones, Caroline B; Searle, Jonathan; Regan, William; Mathur, Sujeev; Boyd, Nicola; Reinhardt, Zdenka; Duignan, Sophie; Prendiville, Terence; Adwani, Satish; Kaski, Juan Pablo |
| Source: |
ESC Heart Failure (2024) (In press). |
| Publisher Information: |
WILEY PERIODICALS, INC |
| Publication Year: |
2024 |
| Collection: |
University College London: UCL Discovery |
| Subject Terms: |
Science & Technology; Life Sciences & Biomedicine; Cardiac & Cardiovascular Systems; Cardiovascular System & Cardiology; Hypertrophic cardiomyopathy; Paediatric cardiology; Inherited cardiac conditions; Genetics; RASopathy; Noonan; Predictors; Arrhythmia; Sudden cardiac death; Mortality; LONG-TERM OUTCOMES; NOONAN SYNDROME; CLINICAL PRESENTATION; CHILDREN; CHILDHOOD; MANAGEMENT; DIAGNOSIS; SOCIETY; DEATH; RISK |
| Description: |
Aims: This study aimed to describe the natural history and predictors of all-cause mortality and sudden cardiac death (SCD)/equivalent events in children with a RASopathy syndrome and hypertrophic cardiomyopathy (HCM). Methods and results: This is a retrospective cohort study from 14 paediatric cardiology centres in the United Kingdom and Ireland. We included children |
| Document Type: |
article in journal/newspaper |
| File Description: |
application/pdf |
| Language: |
English |
| Relation: |
https://discovery.ucl.ac.uk/id/eprint/10187113/ |
| Availability: |
https://discovery.ucl.ac.uk/id/eprint/10187113/1/ESC%20Heart%20Failure%20-%202024%20-%20Boleti%20-%20Natural%20history%20and%20outcomes%20in%20paediatric%20RASopathy%25E2%2580%2590associated%20hypertrophic.pdf; https://discovery.ucl.ac.uk/id/eprint/10187113/ |
| Rights: |
open |
| Accession Number: |
edsbas.B9F61DBA |
| Database: |
BASE |