| Title: |
Deciphering signaling pathways in hematopoietic stem cells: the molecular complexity of Myelodysplastic Syndromes (MDS) and leukemic progression |
| Authors: |
Irene Casalin; Alessia De Stefano; Eleonora Ceneri; Alessandra Cappellini; Carlo Finelli; Antonio Curti; Stefania Paolini; Sarah Parisi; Letizia Zannoni; Jacqueline Boultwood; James A. McCubrey; Pann-Ghill Suh; Giulia Ramazzotti; Roberta Fiume; Stefano Ratti; Lucia Manzoli; Lucio Cocco; Matilde Y. Follo |
| Contributors: |
Casalin, Irene; De Stefano, Alessia; Ceneri, Eleonora; Cappellini, Alessandra; Finelli, Carlo; Curti, Antonio; Paolini, Stefania; Parisi, Sarah; Zannoni, Letizia; Boultwood, Jacqueline; Mccubrey, James A.; Suh, Pann-Ghill; Ramazzotti, Giulia; Fiume, Roberta; Ratti, Stefano; Manzoli, Lucia; Cocco, Lucio; Follo, Matilde Y. |
| Publication Year: |
2024 |
| Collection: |
IRIS Università degli Studi di Bologna (CRIS - Current Research Information System) |
| Subject Terms: |
Myelodysplastic Syndromes Acute myeloid leukemia Phosphoinositide signaling Epigenetic regulation Cytokines secretion Apoptosis |
| Description: |
Myelodysplastic Syndromes, a heterogeneous group of hematological disorders, are characterized by abnormalities in phosphoinositide-dependent signaling, epigenetic regulators, apoptosis, and cytokine interactions within the bone marrow microenvironment, contributing to disease pathogenesis and neoplastic growth. Comprehensive knowledge of these pathways is crucial for the development of innovative therapies that aim to restore normal apoptosis and improve patient outcomes. |
| Document Type: |
article in journal/newspaper |
| File Description: |
STAMPA |
| Language: |
English |
| Relation: |
info:eu-repo/semantics/altIdentifier/pmid/38242820; info:eu-repo/semantics/altIdentifier/wos/WOS:001202864900001; volume:91; firstpage:1; lastpage:8; numberofpages:8; journal:ADVANCES IN BIOLOGICAL REGULATION; https://hdl.handle.net/11585/1010555; https://doi.org/10.1016/j.jbior.2024.101014 |
| DOI: |
10.1016/j.jbior.2024.101014 |
| Availability: |
https://hdl.handle.net/11585/1010555; https://doi.org/10.1016/j.jbior.2024.101014 |
| Rights: |
info:eu-repo/semantics/openAccess |
| Accession Number: |
edsbas.BBC7D76B |
| Database: |
BASE |