| Title: |
Stereometric parameters change vs. HRT Topographic Change Analysis (TCA) agreement in early detection of glaucoma progression |
| Authors: |
POPA CHERECHEANU, A; DASCALU, AM; SERBAN, D; STANA, D |
| Source: |
Acta Ophthalmologica ; volume 90, issue s249, page 0-0 ; ISSN 1755-375X 1755-3768 |
| Publisher Information: |
Wiley |
| Publication Year: |
2012 |
| Collection: |
Wiley Online Library (Open Access Articles via Crossref) |
| Description: |
Purpose To investigate the sensitivity and specificity of the stereometric parameters change analyses vs. TCA in early detection of glaucoma progression. Methods 81 patients with POAG were monitored for 4 years: GAT (monthly), SAP (every 6 months), optic disc photographs and HRT3 (yearly). The exclusion criteria were optic disc or retinal pathology that might interfere with the detection of glaucoma progression, TSD >30 and inter‐test variation of RH above 25 μm for all HRT exams. The criterion for structural progression was considered at least 20 adjacent super‐pixels with clinically significant decrease in height (>5%). Results 16 patients of total 81 presented structural progression on TCA. The most useful stereometric parameters for early detection of glaucoma progression were: Rim Area change (sensitivity 100%, specificity 74.2% for a “cut off” value of ‐0.05), C/D Area change (sensitivity 85.7%, specificity 71.5% for a “cut off” value of 0.02), C/D linear change (sensitivity 85.7%, specificity 71.5% for a “cut off” value of 0.02), Rim Volume change (sensitivity 71.4%, specificity 88.8% for a “cut off” value of ‐0.04). RNFL Thickness change ( |
| Document Type: |
article in journal/newspaper |
| Language: |
English |
| DOI: |
10.1111/j.1755-3768.2012.f022.x |
| DOI: |
10.1111/j.1755-3768.2012.F022.x/fullpdf |
| Availability: |
https://doi.org/10.1111/j.1755-3768.2012.f022.x; http://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1111%2Fj.1755-3768.2012.F022.x; http://onlinelibrary.wiley.com/wol1/doi/10.1111/j.1755-3768.2012.F022.x/fullpdf |
| Rights: |
http://onlinelibrary.wiley.com/termsAndConditions#vor |
| Accession Number: |
edsbas.BC5C7459 |
| Database: |
BASE |