| Title: |
Test-retest repeatability of myocardial radiomic features from quantitative cardiac magnetic resonance T1 and T2 mapping |
| Authors: |
Marfisi D.; Giannelli M.; Marzi C.; Del Meglio J.; Barucci A.; Masturzo L.; Vignali C.; Mascalchi M.; Traino A.; Casolo G.; Diciotti S.; Tessa C. |
| Contributors: |
Marfisi, D.; Giannelli, M.; Marzi, C.; Del Meglio, J.; Barucci, A.; Masturzo, L.; Vignali, C.; Mascalchi, M.; Traino, A.; Casolo, G.; Diciotti, S.; Tessa, C. |
| Publication Year: |
2024 |
| Collection: |
IRIS Università degli Studi di Bologna (CRIS - Current Research Information System) |
| Subject Terms: |
Cardiac T1 and T2 mapping; Magnetic resonance imaging; Radiomic; Test-retest repeatability |
| Description: |
Radiomics of cardiac magnetic resonance (MR) imaging has proved to be potentially useful in the study of various myocardial diseases. Therefore, assessing the repeatability degree in radiomic features measurement is of fundamental importance. The aim of this study was to assess test-retest repeatability of myocardial radiomic features extracted from quantitative T1 and T2 maps. A representative group of 24 subjects (mean age 54 ± 18 years) referred for clinical cardiac MR imaging were enrolled in the study. For each subject, T1 and T2 mapping through MOLLI and T2-prepared TrueFISP acquisition sequences, respectively, were performed at 1.5 T. Then, 98 radiomic features of different classes (shape, first-order, second-order) were extracted from a region of interest encompassing the whole left ventricle myocardium in a short axis slice. The repeatability was assessed performing different and complementary analyses: intraclass correlation coefficient (ICC) and limits of agreement (LOA) (i.e., the interval within which 95% of the percentage differences between two repeated measures are expected to lie). Radiomic features were characterized by a relatively wide range of repeatability degree in terms of both ICC and LOA. Overall, 44.9% and 38.8% of radiomic features showed ICC values > 0.75 for T1 and T2 maps, respectively, while 25.5% and 23.4% of radiomic features showed LOA between ±10%. A subset of radiomic features for T1 (Mean, Median, 10Percentile, 90Percentile, RootMeanSquared, Imc2, RunLengthNonUniformityNormalized, RunPercentage and ShortRunEmphasis) and T2 (MaximumDiameter, RunLengthNonUniformityNormalized, RunPercentage, ShortRunEmphasis) maps presented both ICC > 0.75 and LOA between ±5%. Overall, radiomic features extracted from T1 maps showed better repeatability performance than those extracted from T2 maps, with shape features characterized by better repeatability than first-order and textural features. Moreover, only a limited subset of 9 and 4 radiomic features for T1 and T2 maps, respectively, ... |
| Document Type: |
article in journal/newspaper |
| File Description: |
STAMPA |
| Language: |
English |
| Relation: |
info:eu-repo/semantics/altIdentifier/pmid/39067653; info:eu-repo/semantics/altIdentifier/wos/WOS:001290004100001; volume:113; firstpage:1; lastpage:10; numberofpages:10; journal:MAGNETIC RESONANCE IMAGING; https://hdl.handle.net/11585/1013349; https://www.sciencedirect.com/science/article/pii/S0730725X24001929 |
| DOI: |
10.1016/j.mri.2024.110217 |
| Availability: |
https://hdl.handle.net/11585/1013349; https://doi.org/10.1016/j.mri.2024.110217; https://www.sciencedirect.com/science/article/pii/S0730725X24001929 |
| Rights: |
info:eu-repo/semantics/openAccess |
| Accession Number: |
edsbas.BD52795D |
| Database: |
BASE |