| Title: |
Nutrient status and intakes of adults with phenylketonuria |
| Authors: |
Venegas, Eva; Langeveld, Simone; Ahring, Kirsten; Benitez, Rosa; Desloovere, An; Dios, Elena; Gómez, Eva; Hermida, Alvaro; Marsaux, Cyril; VERLOO, PATRICK; Couce, Maria-Luz |
| Source: |
NUTRIENTS ; ISSN: 2072-6643 |
| Publication Year: |
2024 |
| Collection: |
Ghent University Academic Bibliography |
| Subject Terms: |
Biology and Life Sciences; Medicine and Health Sciences; phenylalanine hydroxylase deficiency; nutritional status; amino acid; micronutrient; cognitive wellbeing; FACT-COG; PKU; DEFICIENCY; CANCER; RISK |
| Description: |
A phenylalanine-restricted diet, supplemented with protein substitutes (PSs), remains the cornerstone of phenylketonuria (PKU) management. However, adherence is challenging in adulthood, and data on the nutritional status of early and continuously treated adults with PKU (ETAwPKU) are scarce. A total of 34 ETAwPKU (16 females; mean ± SD, age: 28 ± 9 years, phenylalanine concentration: 847 ± 285 µmol/L) and 34 age- and sex-matched control subjects were compared regarding their blood nutrient status, self-reported dietary intake, and cognitive wellbeing. Though diet adherence varied, all ETAwPKU were taking a PS. No significant differences were found for blood DHA, calcium, ferritin, transferrin, and zinc concentrations. However, selenium and ubiquinone concentrations were 16% and 29% lower in ETAwPKU, respectively ( p < 0.01 and |
| Document Type: |
article in journal/newspaper |
| File Description: |
application/pdf |
| Language: |
English |
| Relation: |
https://biblio.ugent.be/publication/01JCGW9T7YGEXYVC146Z132WBE; https://doi.org/10.3390/nu16162724; https://biblio.ugent.be/publication/01JCGW9T7YGEXYVC146Z132WBE/file/01JCGWBF7YPE3GYS2GJD0AVREK |
| DOI: |
10.3390/nu16162724 |
| Availability: |
https://biblio.ugent.be/publication/01JCGW9T7YGEXYVC146Z132WBE; https://hdl.handle.net/1854/LU-01JCGW9T7YGEXYVC146Z132WBE; https://doi.org/10.3390/nu16162724; https://biblio.ugent.be/publication/01JCGW9T7YGEXYVC146Z132WBE/file/01JCGWBF7YPE3GYS2GJD0AVREK |
| Rights: |
info:eu-repo/semantics/openAccess |
| Accession Number: |
edsbas.BDB531E6 |
| Database: |
BASE |