| Title: |
PF711 DIFFERENCES IN PERCEPTIONS ON TREATMENT APPROACHES BETWEEN PHYSICIANS AND ITP PATIENTS: RESULTS FROM THE ITP WORLD IMPACT SURVEY (I‐WISH) |
| Authors: |
Kruse, A.; Kruse, C.; Morgan, M.; Bussel, J.; Provan, D.; Ghanima, W.; Hou, M.; Santoro, C.; Michel, M.; Lovrencic, B.; Waller, J.; Stankovic, M.; Tomiyama, Y. |
| Source: |
HemaSphere ; volume 3, issue S1, page 310-311 ; ISSN 2572-9241 2572-9241 |
| Publisher Information: |
Wiley |
| Publication Year: |
2019 |
| Collection: |
Wiley Online Library (Open Access Articles via Crossref) |
| Description: |
Background: Guidelines recommend that adult patients (pts) with persistent or chronic immune thrombocytopenia (ITP) who are corticosteroid (CS) dependent or unresponsive to 1st‐line CS therapy be treated with splenectomy, rituximab, or a thrombopoietin receptor agonist (TPO‐RA). Aims: I‐WISh studied the burden of ITP and its quality of life impact using a global pts and physicians (MDs) sampling frame. MDs and ITP pts beliefs, perceptions, and attitudes about treatment are reported. Methods: I‐WISh is a cross‐sectional survey of 1507 ITP pts and 472 MDs across 13 countries; pts were recruited via MDs and pt support groups. The survey captured demographics, signs and symptoms, impact of symptoms, and pt–MD relationships. An expert MD and pt advocacy ITP specialist steering committee designed and endorsed the survey materials. Results: MDs mean no. of current and newly diagnosed ITP pts (SD) in the past year were 34 (50) and 18 (36), respectively. Pts were provided with a list of treatments and selected all that applied to them. Amongst treatments pts received at any time, CSs (79%) were the most common, followed by intravenous immunoglobulin (IVIg; 48%), other immunosuppressants (ISs; 15%), Rho[D] immune globulin (anti‐D; 13%), and cyclosporine (10%). TPO‐RAs and anti‐CD20 were used overall in 30% and 26% of pts, respectively. More pts used a TPO‐RA (17%) compared with anti‐CD20 (5%), whilst 26% of pts used CSs at the time of survey. MDs were more likely to prescribe CSs over TPO‐RAs across the platelet level |
| Document Type: |
article in journal/newspaper |
| Language: |
English |
| DOI: |
10.1097/01.hs9.0000561128.85171.c0 |
| DOI: |
10.1097/01.HS9.0000561128.85171.c0 |
| Availability: |
http://dx.doi.org/10.1097/01.hs9.0000561128.85171.c0; https://onlinelibrary.wiley.com/doi/pdf/10.1097/01.HS9.0000561128.85171.c0 |
| Rights: |
http://onlinelibrary.wiley.com/termsAndConditions#vor |
| Accession Number: |
edsbas.BE371307 |
| Database: |
BASE |