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Tracheal intubation in the critically ill patient

Title: Tracheal intubation in the critically ill patient
Authors: Russotto, Vincenzo; Rahmani, Lua S; Parotto, Matteo; Bellani, Giacomo; Laffey, John G
Contributors: Russotto, Vincenzo; Rahmani, Lua S; Parotto, Matteo; Bellani, Giacomo; Laffey, John G
Publication Year: 2022
Collection: Università degli Studi di Trento: CINECA IRIS
Subject Terms: Critical Care; intubation; artificial airway
Description: Tracheal intubation is among the most commonly performed and high-risk procedures in critical care. Indeed, 45% of patients undergoing intubation experience at least one major peri-intubation adverse event, with cardiovascular instability being the most common event reported in 43%, followed by severe hypoxemia in 9% and cardiac arrest in 3% of cases. These peri-intubation adverse events may expose patients to a higher risk of 28-day mortality, and they are more frequently observed with an increasing number of attempts to secure the airway. The higher risk of peri-intubation complications in critically ill patients, compared with the anaesthesia setting, is the consequence of their deranged physiology (e.g. underlying respiratory failure, shock and/or acidosis) and, in this regard, airway management in critical care has been defined as "physiologically difficult". In recent years, several randomised studies have investigated the most effective preoxygenation strategies, and evidence for the use of positive pressure ventilation in moderate-to-severe hypoxemic patients is established. On the other hand, evidence on interventions to mitigate haemodynamic collapse after intubation has been elusive. Airway management in COVID-19 patients is even more challenging because of the additional risk of infection for healthcare workers, which has influenced clinical choices in this patient group. The aim of this review is to provide an update of the evidence for intubation in critically ill patients with a focus on understanding peri-intubation risks and evaluating interventions to prevent or mitigate adverse events.
Document Type: article in journal/newspaper
File Description: STAMPA
Language: English
Relation: info:eu-repo/semantics/altIdentifier/pmid/34799497; info:eu-repo/semantics/altIdentifier/wos/WOS:000784812100010; volume:39; issue:5; firstpage:46301; lastpage:47210; numberofpages:910; journal:EUROPEAN JOURNAL OF ANAESTHESIOLOGY; https://hdl.handle.net/11572/386392; https://journals.lww.com/ejanaesthesiology/fulltext/2022/05000/tracheal_intubation_in_the_critically_ill_patient.8.aspx
DOI: 10.1097/EJA.0000000000001627
Availability: https://hdl.handle.net/11572/386392; https://doi.org/10.1097/EJA.0000000000001627; https://journals.lww.com/ejanaesthesiology/fulltext/2022/05000/tracheal_intubation_in_the_critically_ill_patient.8.aspx
Rights: info:eu-repo/semantics/closedAccess ; license:Tutti i diritti riservati (All rights reserved) ; license uri:iris.PRI01
Accession Number: edsbas.BF2A3690
Database: BASE