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Orlistat, sibutramine, or combination therapy: Which performs better on waist circumference in relation with body mass index in obese patients?

Title: Orlistat, sibutramine, or combination therapy: Which performs better on waist circumference in relation with body mass index in obese patients?
Authors: Dagar, A; Duman, C; Topsever, P; Karasakal, M; Kaya, A; Aydin, N
Publication Year: 2004
Description: The aim of this study was to evaluate decrease in waist circumference in obese patients receiving different anti-obesity treatments. The study was designed as a short-term (12 weeks), open-label, and randomized trial. Eighty six patients (70 females, 81.4%; mean age 41.09+/-8.73 years, mean BMI 36.1+/-4.3 kg/m(2)) were randomized to four different therapy groups. The primary outcome parameters were waist circumference and body mass index (BMI). The therapy groups were a) diet+ sibutramine 1x10 mg/d (n=22), b) diet+orlistat 3x 120 mg/d (n=25), c) combination of diet+sibutramine+orlistat (n=20) and d) diet (n=19). Combination therapy was more effective than diet and orlistat mono-therapy (p
Document Type: article in journal/newspaper
Language: English
DOI: 10.1620/tjem.202.173
Availability: https://doi.org/10.1620/tjem.202.173; https://avesis.kocaeli.edu.tr/publication/details/7972ae25-07d9-4717-ad71-4aa8eeb0c567/oai
Rights: info:eu-repo/semantics/openAccess
Accession Number: edsbas.C06C906F
Database: BASE