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Acute kidney injury in critically ill patients with COVID–19: The AKICOV multicenter study in Catalonia

Title: Acute kidney injury in critically ill patients with COVID–19: The AKICOV multicenter study in Catalonia
Authors: Vega Sánchez, Arsenio de la; Navas Pérez, Ana; Pérez Carrasco, Marcos; Torrens Sonet, María; Díaz Buendía, Yolanda; Ortiz Ballujera, Patricia; Rodríguez López, Miguel; Sabater Riera, Joan; Olmo Isasmendi, Aitor; Vendrell Torra, Ester; Álvarez García-Pumarino, María; Ibarz Villamayor, Mercedes; Catalán Ibars, Rosa María; Oliva Zelaya, Iban; Pardos Chica, Javier; Rovira Anglès, Conxita; Tomasa Irriguible, Teresa M.; Baró Serra, Anna; Casanova, Edward J.; González de Molina, Francisco Javier; AKICOV Group
Source: Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL))
Publisher Information: Public Library of Science (PLoS)
Publication Year: 2023
Collection: Dipòsit Digital de la Universitat de Barcelona
Subject Terms: COVID-19; Insuficiència renal; Renal insufficiency
Description: This study describes the incidence, evolution and prognosis of acute kidney injury (AKI) in critical COVID-19 during the first pandemic wave. We performed a prospective, observational, multicenter study of confirmed COVID-19 patients admitted to 19 intensive care units (ICUs) in Catalonia (Spain). Data regarding demographics, comorbidities, drug and medical treatment, physiological and laboratory results, AKI development, need for renal replacement therapy (RRT) and clinical outcomes were collected. Descriptive statistics and logistic regression analysis for AKI development and mortality were used. A total of 1,642 patients were enrolled (mean age 63 (15.95) years, 67.5% male). Mechanical ventilation (MV) was required for 80.8% and 64.4% of these patients, who were in prone position, while 67.7% received vasopressors. AKI at ICU admission was 28.4% and increased to 40.1% during ICU stay. A total of 172 (10.9%) patients required RRT, which represents 27.8% of the patients who developed AKI. AKI was more frequent in severe acute respiratory distress syndrome (ARDS) ARDS patients (68% vs 53.6%, p
Document Type: article in journal/newspaper
File Description: 13 p.; application/pdf
Language: English
Relation: Reproducció del document publicat a: https://doi.org/10.1371/journal.pone.0284248; PLOS ONE, 2023, vol. 18, num. 4; https://doi.org/10.1371/journal.pone.0284248; https://hdl.handle.net/2445/204324
Availability: https://hdl.handle.net/2445/204324
Rights: cc by (c) Sanmartín-Fernández, Marcelo et al., 2023 ; http://creativecommons.org/licenses/by/3.0/es/ ; info:eu-repo/semantics/openAccess
Accession Number: edsbas.C0B829FC
Database: BASE