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Apolipoprotein E ε4 is not associated with cognitive impairment in patients with idiopathic REM sleep behavior disorder

Title: Apolipoprotein E ε4 is not associated with cognitive impairment in patients with idiopathic REM sleep behavior disorder
Authors: Sunwoo, JS; Byun, JI; Jun, JS; Kim, TJ; Shin, JW; Kim, HJ; Jung, KY
Contributors: 112418; Kim, TJ
Publication Year: 2021
Subject Terms: Aged; Alleles; Apolipoprotein E4; Cognitive Dysfunction; Cross-Sectional Studies; Female; Genotype; Humans; Male; Neuropsychological Tests; REM Sleep Behavior Disorder; Cognitive impairment; Synucleinopathy
Description: We analyzed 136 patients (age, 67.5 ± 6.9 years; men, 59.6%) with idiopathic rapid eye movement sleep behavior disorder (iRBD). The results of the neuropsychological tests were not significantly different between APOE ε4 carriers and noncarriers, suggesting that the APOE ε4 allele was not associated with cognitive impairment in iRBD.
Document Type: article in journal/newspaper
Language: English
Relation: J013538020; http://repository.ajou.ac.kr/handle/201003/23941
DOI: 10.1016/j.parkreldis.2021.10.002
Availability: http://repository.ajou.ac.kr/handle/201003/23941; https://doi.org/10.1016/j.parkreldis.2021.10.002
Accession Number: edsbas.C1030F07
Database: BASE