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Cl 3 Al-PH 3 Is a Weak Lewis Pair Allowing the Synthesis of Sterically Highly Hindered Primary and Secondary Alkyl Phosphanes

Title: Cl 3 Al-PH 3 Is a Weak Lewis Pair Allowing the Synthesis of Sterically Highly Hindered Primary and Secondary Alkyl Phosphanes
Authors: Oswald, Jan; Fekete, Csilla; Baker, Matt; Bispinghoff, Mark; Pringle, Paul G; Weferling, Norbert; Benkő, Zoltán; Grützmacher, Hansjörg
Source: Oswald, J, Fekete, C, Baker, M, Bispinghoff, M, Pringle, P G, Weferling, N, Benkő, Z & Grützmacher, H 2025, 'Cl 3 Al-PH 3 Is a Weak Lewis Pair Allowing the Synthesis of Sterically Highly Hindered Primary and Secondary Alkyl Phosphanes', Angewandte Chemie (International ed. in English), vol. 64, no. 29, e202501656. https://doi.org/10.1002/anie.202501656
Publication Year: 2025
Collection: University of Bristol: Bristol Reserach
Description: Phosphane (PH 3 ) gas has the highest phosphorus content of all commercial phosphorus compounds, yet its use for valuable chemicals is very limited. Aluminum chloride and phosphane yield quantitatively the adduct Cl 3 Al-PH 3 , which is easy to handle and reacts with a large set of alkyl halides to give phosphonium salts that can be converted to primary phosphanes. This sequence has been generalized to access various secondary and some tertiary phosphanes in excellent yields under mild conditions and short reaction times. With unprecedented ease, these reactions allow, in particular, the preparation of sterically demanding phosphanes, which, as ligands, are key components of highly catalytically competent transition metal complexes.
Document Type: article in journal/newspaper
Language: English
Relation: info:eu-repo/semantics/altIdentifier/pmid/40129366; info:eu-repo/semantics/altIdentifier/hdl/https://hdl.handle.net/1983/521142e1-577c-4874-a38e-2483379184f3
DOI: 10.1002/anie.202501656
Availability: https://hdl.handle.net/1983/521142e1-577c-4874-a38e-2483379184f3; https://research-information.bris.ac.uk/en/publications/521142e1-577c-4874-a38e-2483379184f3; https://doi.org/10.1002/anie.202501656
Rights: info:eu-repo/semantics/openAccess ; http://creativecommons.org/licenses/by/4.0/
Accession Number: edsbas.C1325750
Database: BASE