| Title: |
Bone quality assessed using quantitative ultrasound at the distal radius does not differ in antiretroviral therapy-naïve HIV-positive and HIV-negative Rwandan women |
| Authors: |
Mutimura, E.; Shi, Q.; Hoover, D.R.; Anastos, K.; Rudakemwa, E.; Dusingize, J.C.; Sinabye, J.D.; Yin, M.T. |
| Publisher Information: |
Wiley-Blackwell |
| Publication Year: |
2016 |
| Subject Terms: |
Health Policy; Pharmacology (medical); Infectious Diseases; demo; socio |
| Description: |
ObjectivesThe incidence of fractures appears to be increased in HIV-infected individuals.MethodsWe assessed bone quality using quantitative ultrasound (QUS) in HIV-infected and uninfected Rwandan women. A Sunlight Omnisense 7000 QUS was used to measure the speed of ultrasound (SOS) at the distal radius in 646 antiretroviral therapy (ART)-naive HIV-infected women and 211 HIV-uninfected women. The Z-scores for SOS were based on data for women of the same age from the manufacturer's reference material.ResultsThe mean CD4 cell count was 285 (+/- 166) cells/mu L in the HIV-positive women. SOS Z-scores adjusted and unadjusted for body mass index did not differ between the groups. SOS did not differ by CD4 count (= 200 cells/mu L: 4016 (+/- 117) vs. 4028 (+/- 107) m/s, respectively; p=0.19.ConclusionsIn HIV-positive ART-naive Rwandan women with advanced HIV disease, bone quality at the distal radius was similar to that in HIV-negative controls. |
| Document Type: |
article in journal/newspaper |
| Language: |
English |
| Relation: |
https://espace.library.uq.edu.au/view/UQ:7342dd5 |
| Availability: |
https://espace.library.uq.edu.au/view/UQ:7342dd5 |
| Rights: |
undefined |
| Accession Number: |
edsbas.C19DB903 |
| Database: |
BASE |