| Title: |
Impact of perioperative fluid administration on early outcomes after pancreatoduodenectomy: A meta-analysis (Review) |
| Authors: |
Huang, Y; Chua, TC; Gill, AJ; Samra, JS |
| Publisher Information: |
Elsevier BV |
| Publication Year: |
2017 |
| Collection: |
Griffith University: Griffith Research Online |
| Subject Terms: |
Clinical sciences; Fluid regimen; Pancreatic cancer; Pancreatoduodenectomy; Perioperative outcomes |
| Description: |
Background Pancreatoduodenectomy (PD) remains a technically challenging surgical procedure with morbidity rates ranging between 30 and 50%. It is suggested that the liberal use of fluids is associated with a poor perioperative outcome. This review examines the impact of fluid administration on outcomes after PD. Methods A literature search was conducted using the MEDLINE, EMBASE and PubMed database (June 1966–June 2016). Studies identified were appraised with standard selection criteria. Data points were extracted and meta-analysis was performed according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA). Results Eleven studies, seven retrospective trials and four randomized control trials comprising 2842 patients were included. Seven studies were meta-analyzed. There was no difference in length of hospital stay (P = 0.25), pancreas specific complications (P = 0.20), pulmonary (P = 0.58), cardiovascular (P = 0.75), gastrointestinal (P = 0.49), hepatobiliary (P = 0.53), urogenital (P = 0.42), wound complication (P = 0.79), reoperation rate (P = 0.69), overall morbidity (P = 0.18), major morbidity (P = 0.91), 30-day mortality (P = 0.07) and 90-day mortality (P = 0.58) in low or high fluid groups. Conclusion The current available data fails to demonstrate an association between the amount of perioperative intravenous fluid administration and postoperative complications in patients undergoing PD. ; No Full Text |
| Document Type: |
article in journal/newspaper |
| Language: |
English |
| Relation: |
Pancreatology; Huang, Y; Chua, TC; Gill, AJ; Samra, JS, Impact of perioperative fluid administration on early outcomes after pancreatoduodenectomy: A meta-analysis (Review), Pancreatology, 2017, 17 (3), pp. 334-341; https://hdl.handle.net/10072/408953 |
| DOI: |
10.1016/j.pan.2017.02.014 |
| Availability: |
https://hdl.handle.net/10072/408953; https://doi.org/10.1016/j.pan.2017.02.014 |
| Rights: |
open access |
| Accession Number: |
edsbas.C1AC1FA5 |
| Database: |
BASE |