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Assessment of agreement using the equine glandular gastric disease grading system in 84 cases

Title: Assessment of agreement using the equine glandular gastric disease grading system in 84 cases
Authors: Pratt, Stefanie; Bowen, Ian; Hallowell, Gayle; Shipman, Emma; Redpath, Adam
Publisher Information: Wiley Open Access
Publication Year: 2022
Collection: University of Nottingham: Repository@Nottingham
Subject Terms: ECEIM guidelines; equine; equine glandular gastric disease (EGGD); grading system
Description: Introduction: Equine glandular gastric disease (EGGD) is a common condition causing signs of gastric pain although lesions are highly variable in their appearance. The only definitive method to diagnose EGGD ante-mortem is gastroscopy. The current recommended method for describing these lesions is the European College of Equine Internal Medicine (ECEIM) guidelines; however, repeatability between users is variable. This study aimed to validate the reliability of lesion descriptions using ECEIM consensus guidelines, using four blinded equine internal medicine diplomates. Methods: Ninety-two horses with EGGD with pre- and post-treatment gastroscopy images were identified using the electronic record at a UK equine hospital between 2012 and 2019. Eight horses were excluded due to non-diagnostic images. Four blinded observers used the recommended grading system to describe images and outcomes. Intraclass correlation coefficients and Krippendorff's alpha were used to determine reliability and agreement, respectively. Results: Intraclass correlation coefficient for severity was 0.782 (95% confidence interval [CI] 0.722–0.832), for distribution was 0.671 (95% CI 0.540–0.763), for the descriptor raised was 0.635 (95% CI 0.479–0.741), fibrinosuppurative was 0.745 (95% CI 0.651–0.812), haemorrhagic was 0.648 (95% CI 0.513–0.744), hyperaemic was 0.389 (95% CI 0.232–0.522) and for outcome was 0.677 (95% CI 0.559–0.770). Krippendorff's alpha for severity was 0.466 (95% CI 0.466–0.418), for distribution was 0.304 (95% CI 0.234–0.374), for the descriptor raised was 0.268 (95% CI 0.207–0.329), fibrinosuppurative was 0.406 (95% CI 0.347–0.463), haemorrhagic was 0.287 (95% CI 0.229–0.344), hyperaemic was 0.112 (95% CI 0.034–0.188) and for outcome was 0.315 (95% CI 0.218–0.408). There was moderate reliability determined between observers using intra-class correlation coefficients and unacceptable agreement determined between observers using Krippendorff's alpha. Discussion: These results suggest that the current grading system is ...
Document Type: article in journal/newspaper
Language: English
Relation: https://nottingham-repository.worktribe.com/output/46469470; Veterinary Medicine and Science; Volume 8; Issue 4; Pagination 1472-1477
DOI: 10.1002/vms3.807
Availability: https://doi.org/10.1002/vms3.807; https://nottingham-repository.worktribe.com/file/46469470/1/Assessment%20of%20agreement%20using%20the%20equine%20glandular%20gastric%20disease%20grading%20system%20in%2084%20cases; https://nottingham-repository.worktribe.com/output/46469470
Rights: openAccess ; https://creativecommons.org/licenses/by/4.0/
Accession Number: edsbas.C1CA8FAE
Database: BASE