Assessment of Patients with Intracerebral Hemorrhage or Hemorrhagic Transformation in the VENOST Study
| Title: | Assessment of Patients with Intracerebral Hemorrhage or Hemorrhagic Transformation in the VENOST Study |
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| Authors: | Taşkın Duman; Vildan Yayla; Derya Uludüz; Eylem Özaydın Göksu; Vedat Ali Yürekli; Hamit Genç; Uygar Utku; Nilgün Çınar; Hakan Tekeli; Mehmet Ali Sungur; Firdevs Ezgi Tokuç; Nevzat Uzuner; Mehmet Güney Şenol; Arda Yılmaz; Mustafa Gökçe; Seden Demirci; Özge Yılmaz Küsbeci; Gülnur Tekgöl Uzuner; Şevki Şahin; Hale Zeynep Batur Çağlayan; Mustafa Açıkgöz; Fatih Özdağ; Sevim Baybaş; Hakan Ekmekçi; Murat Çabalar; Mehmet Yaman; Hesna Bektaş; Yüksel Kaplan; Başak Karakurum Göksel; Aysel Milanlıoğlu; Dilek Necioğlu Örken; Mehmet Ufuk Aluçlu; Sena Çolakoğlu; Ahmet Tüfekçi; Mustafa Bakar; Bijrn Nazlıel; Nida Taşçılar; Baki Göksan; Hasan Hüseyin Kozak; Handan Mısırlı; Hayriye Küçükoğlu; İpek Midi; Necdet Mengüllüoğlu; Emrah Aytaç; Nilüfer Yeşilot; Birsen İnce; Osman Özgür Yalın; Taşkın Güneş; Serdar Oruç; Füsun Mayda Domaç; Şerefnur Öztürk; Ali Karahan; Hacı Ali Erdoğan; Nazire Afşar |
| Publisher Information: | S. Karger AG |
| Publication Year: | 2025 |
| Subject Terms: | Adult; Male; Adolescent; Middle Aged; Cerebral hemorrhage; 3. Good health; Sinus Thrombosis; Intracranial; Young Adult; 03 medical and health sciences; 0302 clinical medicine; VENOST; Cerebral venous thrombosis; Risk Factors; Humans; Female; Aged; Retrospective Studies |
| Time: | 610; 616 |
| Description: | Introduction: Cerebral venous and sinus thrombosis (CVST) may lead to cerebral edema and increased intracranial pressure; besides, ischemic or hemorrhagic lesions may develop. Intracerebral hemorrhages occur in approximately one-third of CVST patients. We assessed and compared the findings of the cerebral hemorrhage (CH) group and the CVST group. Materials and Methods: In the VENOST study, medical records of 1,193 patients with CVST, aged over 18 years, were obtained from 35 national stroke centers. Demographic characteristics, clinical symptoms, signs at the admission, radiological findings, etiologic factors, acute and maintenance treatment, and outcome results were reported. The number of involved sinuses or veins, localizations of thrombus, and lesions on CT and MRI scans were recorded. Results: CH was detected in the brain imaging of 241 (21.1%) patients, as hemorrhagic infarction in 198 patients and intracerebral hemorrhage in 43 patients. Gynecologic causes comprised the largest percentage (41.7%) of etiology and risk factors in the CVST group. In the CH group, headache associated with other neurological symptoms was more frequent. These neurological symptoms were epileptic seizures (46.9%), nausea and/or vomiting (36.5%), altered consciousness (36.5%), and focal neurological deficits (33.6%). mRS was ≥3 in 23.1% of the patients in the CH group. Discussion and Conclusion: CVST, an important cause of stroke in the young, should be monitored closely if the patients have additional symptoms of headache, multiple sinus involvement, and CH. Older age and parenchymal lesion, either hemorrhagic infarction or intracerebral hemorrhage, imply poor outcome. |
| Document Type: | article in journal/newspaper |
| Language: | unknown |
| Relation: | European Neurology; https://hdl.handle.net/20.500.12628/25283; 000614770900007; 615; 621; 83 |
| DOI: | 10.1159/000510627 |
| Availability: | https://hdl.handle.net/20.500.12628/25283; https://doi.org/10.1159/000510627 |
| Rights: | CLOSED |
| Accession Number: | edsbas.C2394861 |
| Database: | BASE |