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The Ketamine Side Effect Tool (KSET):A comprehensive measurement-based safety tool for ketamine treatment in psychiatry

Title: The Ketamine Side Effect Tool (KSET):A comprehensive measurement-based safety tool for ketamine treatment in psychiatry
Authors: Bayes, Adam; Short, Brooke; Zarate, Carlos A.; Park, Lawrence; Murrough, James W.; McLoughlin, Declan M.; Riva-Posse, Patricio; Schoevers, Robert; Veraart, Jolien; Parikh, Sagar; Glue, Paul; Fam, Johnson; McShane, Rupert; Galvez, Veronica; Martin, Donel; Tor, Phern Chern; Brunoni, Andre; Loo, Colleen K.
Source: Bayes, A, Short, B, Zarate, C A, Park, L, Murrough, J W, McLoughlin, D M, Riva-Posse, P, Schoevers, R, Veraart, J, Parikh, S, Glue, P, Fam, J, McShane, R, Galvez, V, Martin, D, Tor, P C, Brunoni, A & Loo, C K 2022, 'The Ketamine Side Effect Tool (KSET) : A comprehensive measurement-based safety tool for ketamine treatment in psychiatry', Journal of Affective Disorders, vol. 308, pp. 44-46. https://doi.org/10.1016/j.jad.2022.04.020
Publication Year: 2022
Collection: University of Groningen research database
Subject Terms: Antidepressant; Maintenance; Safety; Side effects
Description: Objectives: On a background of the rapidly expanding clinical use of ketamine and esketamine for treatment of depression and other conditions, we examined safety monitoring, seeking to identify knowledge gaps relevant to clinical practice. Methods: An international group of psychiatrists discussed the issue of safety of ketamine and esketamine and came to a consensus on key safety gaps. Results: There is no standard safety monitoring for off-label generic ketamine. For intranasal esketamine, each jurisdiction providing regulatory approval may specify monitoring. Treatment is often provided beyond the period for which safety has been demonstrated, with no agreed framework for monitoring of longer term side effects for either generic ketamine or intranasal esketamine. Limitations: The KSET has established face and content validity, however it has not been validated against other measures of safety. Conclusions: We recommend the Ketamine Side Effect Tool (KSET) as a comprehensive safety monitoring tool for acute and longer term side effects.
Document Type: article in journal/newspaper
File Description: application/pdf
Language: English
ISSN: 0165-0327; 1573-2517
Relation: info:eu-repo/semantics/altIdentifier/pmid/35405177; info:eu-repo/semantics/altIdentifier/hdl/https://hdl.handle.net/11370/1d7bff96-7133-48a3-8383-a07f151eb7e9; info:eu-repo/semantics/altIdentifier/pissn/0165-0327; info:eu-repo/semantics/altIdentifier/eissn/1573-2517
DOI: 10.1016/j.jad.2022.04.020
Availability: https://hdl.handle.net/11370/1d7bff96-7133-48a3-8383-a07f151eb7e9; https://research.rug.nl/en/publications/1d7bff96-7133-48a3-8383-a07f151eb7e9; https://doi.org/10.1016/j.jad.2022.04.020; https://pure.rug.nl/ws/files/222673265/1_s2.0_S0165032722003573_main.pdf
Rights: info:eu-repo/semantics/openAccess ; https://www.rug.nl/library/open-access/article-25fa-pilot-end-user-agreement
Accession Number: edsbas.C26226A
Database: BASE