| Title: |
Global burden of listeriosis |
| Authors: |
Maertens de Noordhout, Charline; Devleesschauwer, Brecht; Angulo, Fred J; Haagsma, Juanita A; Havelaar, Arie H; Speybroeck, Niko |
| Contributors: |
McKee, Martin; Ricciardi, Walter; Zeegers Paget, Dineke |
| Source: |
EUROPEAN JOURNAL OF PUBLIC HEALTH ; ISSN: 1101-1262 |
| Publication Year: |
2013 |
| Collection: |
Ghent University Academic Bibliography |
| Subject Terms: |
Agriculture and Food Sciences |
| Description: |
Background: Listeriosis is caused by Listeria monocytogenes, a gram positive and ubiquitous bacterium. The sources of infection with this foodborne pathogen are typically dairy or ready-to-eat foods. It is a rare disease, mostly occurring in risk groups such as elderly, pregnant women and immunocompromised people. Listeriosis is widely underreported in most countries and no global estimation of the disease burden has been conducted until now. The objective of this study is therefore to estimate the annual global number of human illnesses, deaths and Disability-Adjusted Life Years due to listeriosis by synthesizing existing information and knowledge through a systematic literature review. Methods: Data on listeriosis were retrieved through a search of peerreviewed and grey literature (published from 1990-2012) via search terms developed in line with the MeSH nomenclature. National surveillance data were reviewed where available. A multi-level meta-analysis was conducted to calculate listeriosis incidences, number of deaths and DALYs by WHO sub-region and by age group. PERT distributions were used to model uncertainty. To deal with missing data, back-calculations from meningitis to listeriosis-related meningitis were performed. Results: A total of 12 665 references were identified. After excluding duplicate titles, the dataset was reduced to 8049 unique references. After title and abstract screening, 368 papers were retained for extraction and 128 were included in the review. Listeriosis incidence data have been identified for six of the 14 WHO sub-regions. The preliminary median incidence estimates (by 100,000 inhabitants) are 0.31(range = 0.05-0.80) for AMRO A, 0.40 for AMRO B, 0.38 (range = 0.02-1.30) for EURO A, 0.03 (range = 0.00-0.15) for EURO B, 0.17 (range = 0.00-0.37) for EURO C and 0.30 (range = 0.07-0.60) for WPRO A. Proportions of perinatal cases are 17% (range = 12-91) for AMRO A, 21% for EURO A (range = 0-59), 18% for EURO C and 12% for WPRO A (range = 6-19). The case fatality ratio is 15.9% (range = ... |
| Document Type: |
conference object |
| Language: |
English |
| Relation: |
https://biblio.ugent.be/publication/4194334 |
| Availability: |
https://biblio.ugent.be/publication/4194334; https://hdl.handle.net/1854/LU-4194334 |
| Accession Number: |
edsbas.C3017B33 |
| Database: |
BASE |