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Mixed squamous – neuroendocrine carcinoma of the gallbladder: A case report of a rare pathological entity

Title: Mixed squamous – neuroendocrine carcinoma of the gallbladder: A case report of a rare pathological entity
Authors: Rohik Anjum T. Siddeek; Amit Gupta; Krishna Bhukya Sai; Edem Sanketh; Deepak Rajput; Sweety Gupta; Ravi Hari Phulware
Source: Cancer Research, Statistics, and Treatment, Vol 7, Iss 1, Pp 121-125 (2024)
Publisher Information: Wolters Kluwer Medknow Publications
Publication Year: 2024
Collection: Directory of Open Access Journals: DOAJ Articles
Subject Terms: biliary; case report; gallbladder; minen; mixed neuroendocrine-non-neuroendocrine neoplasms; neuroendocrine neoplasms; Neoplasms. Tumors. Oncology. Including cancer and carcinogens; RC254-282
Description: Gallbladder cancers are the most common biliary tract malignancies in the world. Adenocarcinoma constitutes the most common histology in gallbladder cancer. Neuroendocrine neoplasms of the gallbladder account for about 0.5% of all neuroendocrine neoplasms and 2.1% of all gallbladder tumors. They are rare tumors and present with non-specific symptoms such as abdominal pain, weight loss, anorexia, and obstructive jaundice, and, therefore, are often challenging to diagnose and treat. Mixed neuroendocrine-non-neuroendocrine neoplasm is a subtype of neuroendocrine neoplasm. To add to the literature, we report a rare case of a patient who presented with pain in the abdomen and non-bilious vomiting and was diagnosed with mixed neuroendocrine-non-neuroendocrine gallbladder cancer, identified by immunohistochemistry, and treated with palliative chemotherapy. Due to non-specific symptoms, patients may present at an advanced stage. Further, immunohistochemistry may assist in clinching the diagnosis.
Document Type: article in journal/newspaper
Language: English
ISSN: 2590-3233
Relation: http://www.crstonline.com/article.asp?issn=2590-3233;year=2024;volume=7;issue=1;spage=121;epage=125;aulast=T.; https://doaj.org/toc/2590-3233; https://doaj.org/toc/2590-3225; https://doaj.org/article/5bd653cf0ac644cf96d1a619a905f308
DOI: 10.4103/crst.crst_186_23
Availability: https://doi.org/10.4103/crst.crst_186_23; https://doaj.org/article/5bd653cf0ac644cf96d1a619a905f308
Accession Number: edsbas.C3438B48
Database: BASE