| Title: |
Severity of self-reported symptoms and psychological burden 6-months after hospital admission for COVID-19: a prospective cohort study. |
| Authors: |
Eloy, P.; Tardivon, C.; Martin-Blondel, G.; Isnard, M.; Le Turnier, P.; Le Marechal, M.; Cabié, A.; Launay, O.; Tattevin, P.; Senneville, Eric; Ansart, S.; Goehringer, F.; Chirouze, C.; Bousson, L.; Laouénan, C.; Etienne, M.; Nguyen, D.; Ghosn, J.; Duval, X. |
| Contributors: |
Université de Lille; CHU Lille; METRICS : Evaluation des technologies de santé et des pratiques médicales - ULR 2694 |
| Publication Year: |
2024 |
| Collection: |
LillOA (Lille Open Archive - Université de Lille) |
| Subject Terms: |
COVID-19; Sequelae; Persistent symptoms; Risk factors |
| Description: |
Objectives Few studies have reported clinical COVID-19 sequelae six months (M6) after hospital discharge, but none has studied symptom severity. Methods Prevalence and severity of 7 symptoms were estimated until M6 using the self-administered influenza severity scale in COVID-19 hospitalized patients enrolled in the French COVID cohort. Factors associated with severity were assessed by logistic regression. Anxiety, depression and health-related quality of life (HRQL) were also assessed. Results At M6, among the 324 patients (median age 61 years, 63% men, 19% admitted to intensive care during the acute phase), 187/324 (58%) reported at least one symptom, mostly fatigue (47%) and myalgia (23%). Symptom severity was scored, at most, mild in 125 (67%), moderate in 44 (23%) and severe in 18 (10%). Female gender was the sole factor associated with moderate/severe symptom reporting (OR = 1.98, 95%CI=1.13-3.47). Among the 225 patients with psychological assessment, 24 (11%) had anxiety, 18 (8%) depressive symptoms, and their physical HRQL was significantly poorer than the general population (p=0.0005). Conclusion Even if 58% of patients reported ≥1 symptom at M6, less than 7% rated any symptom as severe. Assessing symptoms severity could be helpful to identify patients requiring appropriate medical care. Women may require special attention. ; 112 |
| Document Type: |
article in journal/newspaper |
| File Description: |
application/rdf+xml; charset=utf-8; application/pdf |
| Language: |
English |
| ISSN: |
34517049 |
| Relation: |
International Journal of Infectious Diseases; Int J Infect Dis; http://hdl.handle.net/20.500.12210/90254 |
| Availability: |
https://hdl.handle.net/20.500.12210/90254 |
| Rights: |
Attribution-NonCommercial-NoDerivs 3.0 United States ; info:eu-repo/semantics/openAccess |
| Accession Number: |
edsbas.C36AD583 |
| Database: |
BASE |