| Title: |
Modifications to residential neighbourhood characteristics and risk of 79 common health conditions: a prospective cohort study |
| Authors: |
Kivimäki, M; Batty, GD; Pentti, J; Nyberg, ST; Lindbohm, JV; Ervasti, J; Gonzales-Inca, C; Suominen, SB; Stenholm, S; Sipilä, PN; Dadvand, P; Vahtera, J |
| Contributors: |
Department of Public Health; Clinicum; HUS Neurocenter |
| Publisher Information: |
ELSEVIER SCI IRELAND LTD |
| Publication Year: |
2021 |
| Collection: |
Helsingfors Universitet: HELDA – Helsingin yliopiston digitaalinen arkisto |
| Subject Terms: |
MULTILEVEL; DISEASE; Public health care science; environmental and occupational health |
| Description: |
Background Observational studies have identified a link between unfavourable neighbourhood characteristics and increased risk of morbidity, but it is unclear whether changes in neighbourhoods affect future disease risk. We used a data-driven approach to assess the impact of neighbourhood modification on 79 health outcomes. Methods In this prospective cohort study, we used pooled, individual-level data from two Finnish cohort studies: the Health and Social Support study and the Finnish Public Sector study. Neighbourhood characteristics (mean educational level, median income, and employment rate of residents, and neighbourhood green space) and individual lifestyle factors of community-dwelling individuals were assessed at baseline (at different waves starting between 1998 and 2013). We repeated assessment of neighbourhood characteristics and lifestyle factors approximately 5 years from each baseline assessment, after which follow-up began for health conditions diagnosed according to the WHO International Classification of Diseases for 79 common health conditions using linkage to electronic health records. We used Cox proportional hazard regression models to compute adjusted hazard ratios (HRs) of incident disease associated with neighbourhood characteristics and changes in neighbourhood characteristics over time and logistic regression analysis to compute adjusted odds of association between changes in neighbourhood characteristics and individual lifestyle factors. Findings 114786 individuals (87012 [75.8%] women; mean age 44.4 years [SD 11.1]) had complete data and were included in this cohort study. During 1.17 million person-years at risk, we recorded 164368 new-onset health conditions and 3438 deaths. Favourable changes in neighbourhood characteristics were associated with reduced risk of all-cause mortality and incidence of 19 specific health conditions. Unfavourable changes were correspondingly associated with increased risk of mortality and 27 specific health conditions. Among participants who did not move ... |
| Document Type: |
article in journal/newspaper |
| File Description: |
application/pdf |
| Language: |
English |
| Relation: |
RIS: urn:3C2A8DF03FC3A27A66C795EC09A79319; https://hdl.handle.net/10138/335468; 000655759200016 |
| Availability: |
https://hdl.handle.net/10138/335468 |
| Rights: |
cc_by ; info:eu-repo/semantics/openAccess ; openAccess |
| Accession Number: |
edsbas.C38AD289 |
| Database: |
BASE |