| Title: |
Endometrial malignancies arising on endometrial polyps and precursor lesions |
| Authors: |
Devranoglu, B.; Keyif, B.; Ilhan, G.; Cogendez, E.; Karateke, A.; Eken, M. K.; Kaygusuz, E. I. |
| Contributors: |
Istanbul Zeynep Kamil Maternity & Children''s Diseases Training & Research Hospital ,; 228677 |
| Publication Year: |
2016 |
| Subject Terms: |
KADIN HASTALIKLARI & DOĞUM; Sağlık Bilimleri; Dahili Tıp Bilimleri; İç Hastalıkları; Klinik Tıp (MED); Klinik Tıp; ONKOLOJİ; Tıp; Kadın Hastalıkları ve Doğum; Cerrahi Tıp Bilimleri; Onkoloji |
| Description: |
Introduction: Polyps are covered with endometrial epithelium and composed of varying proportions of gland, stroma, and blood vessels. Traditionally, endometrial polyps are accepted as a precursor of cancer. The aim of this study was to evaluate the relationship between malignancies arising on endometrial polyps and precursor lesions of these malignancies. Materials and Methods: Data of patients who underwent total abdominal hysterectomy because of a malignancy diagnosed on endometrial polyps were obtained retrospectively from pathology archives. Results: When all malignancies on endometrial polyp were considered, 37% of cases were Type I, 55% were Type II, and 7% were carcinosarcoma. Endometrial intraepithelial carcinoma (EIC) was detected as tumor-adjacent areas on the polyp in eight of the patients who were diagnosed with serous carcinoma. Conclusion: The authors found a precursor lesion in 20 (74%) of their patients who showed endometrial malignancy developing on endometrial polyps. Even when an overt malignancy is not detected on polyps in the curettage material, precursor lesions should be carefully searched. |
| Document Type: |
article in journal/newspaper |
| Language: |
English |
| Relation: |
EUROPEAN JOURNAL OF GYNAECOLOGICAL ONCOLOGY; vv_1032021; http://hdl.handle.net/20.500.12627/128969; https://doi.org/10.12892/ejgo3256.2016; 37; 827; 832 |
| DOI: |
10.12892/ejgo3256.2016 |
| Availability: |
https://hdl.handle.net/20.500.12627/128969; https://doi.org/10.12892/ejgo3256.2016 |
| Accession Number: |
edsbas.C393F5A0 |
| Database: |
BASE |