| Title: |
High-yield production of nano-lateral size graphene oxide by high-power ultrasonication |
| Authors: |
Timochenco, L; Costa-Almeida, R; Bogas, D; Silva, FALS; Silva, J; Pereira, A; Magalhães, FD; Pinto, AM |
| Contributors: |
Instituto de Investigação e Inovação em Saúde |
| Publisher Information: |
MDPI |
| Publication Year: |
2021 |
| Collection: |
Repositório Aberto da Universidade do Porto |
| Subject Terms: |
Graphene; Graphene oxide; Nano-materials; Particle size; Stability; Standardization; Surface chemistry; Aqueous dispersions; Average particle size; Biomedical fields; Chemical characterization; Chemical features; Large scale productions; Oxygen functional groups; Productive process |
| Description: |
Nanographene oxide (GOn) constitutes a nanomaterial of high value in the biomedical field. However, large scale production of highly stable aqueous dispersions of GOn is yet to be achieved. In this work, we explored high-power ultrasonication as a method to reduce particle size of GO and characterized the impact of the process on the physicochemical properties of the material. GOn was obtained with lateral dimensions of 99 ± 43 nm and surface charge of -39.9 ± 2.2 mV. High-power ultrasonication enabled an improvement of stability features, particularly by resulting in a decrease of the average particle size, as well as zeta potential, in comparison to GO obtained by low-power exfoliation and centrifugation (287 ± 139 nm; -29.7 ± 1.2 mV). Remarkably, GOn aqueous dispersions were stable for up to 6 months of shelf-time, with a global process yield of 74%. This novel method enabled the production of large volumes of highly concentrated (7.5 mg mL-1) GOn aqueous dispersions. Chemical characterization of GOn allowed the identification of characteristic oxygen functional groups, supporting high-power ultrasonication as a fast, efficient, and productive process for reducing GO lateral size, while maintaining the material’s chemical features. ; This work was financed by FEDER funds through the COMPETE 2020—Operacional Programme for Competitiveness and Internationalisation (POCI), Portugal 2020, and by national funds (PIDDAC) through FCT/MCTES in the framework of the project POCI-01-0145-FEDER-031143, and Base Funding—UIDB/00511/2020 of the Laboratory for Process Engineering, Environment, Biotechnology and Energy—LEPABE. Authors would also like to thank the support of i3S Scientific Platforms and respective funding: HEMS, member of the national infrastructure PPBI—Portuguese Platform of Bioimaging: POCI-01-0145-FEDER-022122; and Biointerfaces and Nanotechnology (BN) Laboratory, Portuguese Funds through FCT, UID/BIM/04293/2019. Artur Pinto thanks the Portuguese Foundation for Science and Technology (FCT) for the financial ... |
| Document Type: |
article in journal/newspaper |
| File Description: |
application/pdf |
| Language: |
English |
| Relation: |
info:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UIDB%2F00511%2F2020/PT; info:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UID%2FBIM%2F04293%2F2019/PT; Materials, vol.14(8):1916; https://www.mdpi.com/1996-1944/14/8/1916; https://hdl.handle.net/10216/152478 |
| DOI: |
10.3390/ma14081916 |
| Availability: |
https://hdl.handle.net/10216/152478; https://doi.org/10.3390/ma14081916 |
| Rights: |
info:eu-repo/semantics/openAccess |
| Accession Number: |
edsbas.C3A7A15D |
| Database: |
BASE |