| Title: |
Hypertension among people living with human immunodeficiency virus in sub-Saharan Africa: a systematic review and meta-analysis |
| Authors: |
Chen, A; Chan, YK; Mocumbi, AO; Ojji, DB; Waite, L; Beilby, J; Codde, J; Dobe, I; Nkeh-Chungag, BN; Damasceno, A; Stewart, S |
| Publisher Information: |
Nature Publishing |
| Publication Year: |
2024 |
| Collection: |
Griffith University: Griffith Research Online |
| Description: |
We performed a systematic review and meta-analysis of hypertension in people living with human immunodeficiency virus (HIV) in sub-Saharan Africa (SSA). We searched the PubMed, Google Scholar, African Index Medicus, and Embase databases to identify studies published from January 1, 2010, to December 31, 2021. We used a random-effects model to estimate the pooled prevalence of hypertension and mean SBP/DBP level on a sex-specific basis. We included 48 studies reporting data on a pooled sample of 193,843 people living with HIV (PLW-HIV) in SSA. The pooled mean SBP/DBP level was 120 (95% CI 113–128)/77 (95%CI 72–82) mmHg, while the overall pooled prevalence of hypertension was 21.9% (95% CI 19.9–23.9%). Further meta-regression analyses suggested that the prevalence of hypertension was 1.33 times greater in males, 1.23 times greater in individuals receiving antiretroviral therapy (ART) and 1.45 times greater in those individuals with a CD4-count ≥ 200. This meta-analysis of the contemporary pattern of BP levels among PLW-HIV in SSA, suggests that around one in five of such individuals also have hypertension. Given the further context of greater access to ART and subsequently greater longevity, study findings support calls to integrate cardiovascular management into routine HIV care. ; Full Text |
| Document Type: |
article in journal/newspaper |
| Language: |
English |
| Relation: |
Scientific Reports; Chen, A; Chan, YK; Mocumbi, AO; Ojji, DB; Waite, L; Beilby, J; Codde, J; Dobe, I; Nkeh-Chungag, BN; Damasceno, A; Stewart, S, Hypertension among people living with human immunodeficiency virus in sub-Saharan Africa: a systematic review and meta-analysis, Scientific Reports, 2024, 14, pp. 16858; https://hdl.handle.net/10072/432632 |
| DOI: |
10.1038/s41598-024-67703-5 |
| Availability: |
https://hdl.handle.net/10072/432632; https://doi.org/10.1038/s41598-024-67703-5 |
| Rights: |
https://creativecommons.org/licenses/by-nc-nd/4.0/ ; © The Author(s) 2024. This article is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License, which permits any non-commercial use, sharing, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if you modified the licensed material. You do not have permission under this licence to share adapted material derived from this article or parts of it. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by-nc-nd/4.0/. ; open access |
| Accession Number: |
edsbas.C3B0553C |
| Database: |
BASE |