| Title: |
Virologic and immunologic outcomes of treatment with integrase inhibitors in a real-world setting: The RESPOND cohort consortium |
| Authors: |
Neesgaard, B; Mocroft, A; Zangerle, R; Wit, F; Lampe, F; Günthard, HF; Necsoi, C; Law, M; Mussini, C; Castagna, A; Monforte, AD; Pradier, C; Chkhartisvilli, N; Reyes-Uruena, J; Vehreschild, JJ; Wasmuth, J-C; Sönnerborg, A; Stephan, C; Greenberg, L; Llibre, JM; Volny-Anne, A; Peters, L; Pelchen-Matthews, A; Vannappagari, V; Gallant, J; Rieger, A; Youle, M; Braun, D; De Wit, S; Petoumenos, K; Borghi, V; Spagnuolo, V; Tsertsvadze, T; Lundgren, J; Ryom, L; RESPOND study group |
| Source: |
PLoS One , 15 (12) , Article e0243625. (2020) |
| Publication Year: |
2020 |
| Collection: |
University College London: UCL Discovery |
| Description: |
Objectives: To compare virologic and immunologic outcomes of integrase inhibitor (INSTI)-containing, contemporary boosted protease inhibitor (PI/b)-containing and non-nucleotide reverse transcriptase inhibitor (NNRTI)-containing regimens in a real-life setting. Methods: Using logistic regression, virologic and immunologic outcomes of INSTI use were compared to outcomes of PI/b or NNRTI treatment 12 months after treatment start or switch, for participants in the RESPOND cohort consortium. A composite treatment outcome (cTO) was used, defining success as viral load (VL) |
| Document Type: |
article in journal/newspaper |
| File Description: |
text |
| Language: |
English |
| Relation: |
https://discovery.ucl.ac.uk/id/eprint/10118727/1/journal.pone.0243625.pdf; https://discovery.ucl.ac.uk/id/eprint/10118727/ |
| Availability: |
https://discovery.ucl.ac.uk/id/eprint/10118727/1/journal.pone.0243625.pdf; https://discovery.ucl.ac.uk/id/eprint/10118727/ |
| Rights: |
open |
| Accession Number: |
edsbas.C44884F5 |
| Database: |
BASE |