| Title: |
8-oxo-7,8-dihydro-2'-deoxyguanosine as a biomarker of oxidative damage in oesophageal cancer patients: lack of association with antioxidant vitamins and polymorphism of hOGG1 and GST |
| Authors: |
Lagadu, Stéphanie; Lechevrel, Mathilde; Sichel, François; Breton, Jean; Pottier, Didier; Couderc, Rémy; Moussa, Fathi; Prevost, Virginie |
| Contributors: |
Groupe Régional d'Etudes sur le CANcer (GRECAN); Université de Caen Normandie (UNICAEN); Normandie Université (NU)-Normandie Université (NU)-Centre Régional de Lutte contre le Cancer François Baclesse Caen (UNICANCER/CRLC); Normandie Université (NU)-UNICANCER-Tumorothèque de Caen Basse-Normandie (TCBN)-UNICANCER-Tumorothèque de Caen Basse-Normandie (TCBN)-IFR146; Normandie Université (NU); Centre Régional de Lutte contre le Cancer François Baclesse Caen (UNICANCER/CRLC); Normandie Université (NU)-UNICANCER-Tumorothèque de Caen Basse-Normandie (TCBN); Service de Chimie Inorganique et Biologique (SCIB - UMR E3); Institut Nanosciences et Cryogénie (INAC); Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Grenoble Alpes 2016-2019 (UGA 2016-2019 )-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Grenoble Alpes 2016-2019 (UGA 2016-2019 )-Centre National de la Recherche Scientifique (CNRS); CHU Trousseau APHP; Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU); Unité de recherche interdisciplinaire pour la prévention et le traitement des cancers (ANTICIPE); Normandie Université (NU)-Normandie Université (NU)-CHU Caen Normandie – Centre Hospitalier Universitaire de Caen Normandie (CHU Caen Normandie); Normandie Université (NU)-Tumorothèque de Caen Basse-Normandie (TCBN)-Tumorothèque de Caen Basse-Normandie (TCBN)-Centre Régional de Lutte contre le Cancer François Baclesse Caen (UNICANCER/CRLC); Normandie Université (NU)-UNICANCER-Tumorothèque de Caen Basse-Normandie (TCBN)-UNICANCER-Institut National de la Santé et de la Recherche Médicale (INSERM) |
| Source: |
ISSN: 1756-9966 ; Journal of experimental & clinical cancer research ; https://normandie-univ.hal.science/hal-02461268 ; Journal of experimental & clinical cancer research, 2010, 29 (1), pp.157. ⟨10.1186/1756-9966-29-157⟩. |
| Publisher Information: |
CCSD; BioMed Central |
| Publication Year: |
2010 |
| Collection: |
Université Grenoble Alpes: HAL |
| Subject Terms: |
MESH: 8-Hydroxy-2'-Deoxyguanosine; MESH: Antioxidants; MESH: Humans; MESH: Oxidative Stress; MESH: Polymorphism; Single Nucleotide; MESH: Vitamins; MESH: Biomarkers; Tumor; MESH: Chromatography; High Pressure Liquid; MESH: DNA Glycosylases; MESH: Deoxyguanosine; MESH: Esophageal Neoplasms; MESH: Genetic Predisposition to Disease; MESH: Glutathione Synthase; [SDV.BBM.BM]Life Sciences [q-bio]/Biochemistry; Molecular Biology/Molecular biology; [SDV.CAN]Life Sciences [q-bio]/Cancer; [SDV.EE.SANT]Life Sciences [q-bio]/Ecology; environment/Health; [SDV.TOX]Life Sciences [q-bio]/Toxicology; [CHIM.ANAL]Chemical Sciences/Analytical chemistry |
| Description: |
International audience ; The present report was designed to investigate the origins of elevated oxidative stress measured in cancer patients in our previous work related to a case-control study (17 cases, 43 controls) on oesophageal cancers. The aim was to characterize the relationship between the levels of 8-oxo-7,8-dihydro-2'-deoxyguanosine (8-oxodG), antioxidant vitamins and genetic susceptibility. |
| Document Type: |
article in journal/newspaper |
| Language: |
English |
| Relation: |
info:eu-repo/semantics/altIdentifier/pmid/21134244; PUBMED: 21134244 |
| DOI: |
10.1186/1756-9966-29-157 |
| Availability: |
https://normandie-univ.hal.science/hal-02461268; https://normandie-univ.hal.science/hal-02461268v1/document; https://normandie-univ.hal.science/hal-02461268v1/file/1756-9966-29-157.pdf; https://doi.org/10.1186/1756-9966-29-157 |
| Rights: |
info:eu-repo/semantics/OpenAccess |
| Accession Number: |
edsbas.C473897D |
| Database: |
BASE |