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Sex-related differences in severe native valvular heart disease : the ESC-EORP Valvular Heart Disease II survey

Title: Sex-related differences in severe native valvular heart disease : the ESC-EORP Valvular Heart Disease II survey
Authors: Mascherbauer, J.; Kammerlander, A.; Nitsche, C.; Bax, J.; Delgado, Victoria; Evangelista Masip, Arturo; Laroche, C.; Maggioni, Aldo P.; Magne, J.; Vahanian, A.; Iung, B.; Zera, E.; Shirka, E.; Dado, E.; Heger, M.; Samadov, F.; Rustamova, Y.; Van Camp, G.; Pasquet, A.; Van de Veire, N.; Cosyns, Bernard; Sindelarova, S.; Linhartova, K.; Ihlemann, N.; Ali, H.H.; Hassan, M.; Ahmed, Y.A.A.; Sadek, Y.; Abdelhamid, Magdy; Ghareeb, H.S.; Kazamel, G.; Kylmälä, M.M.; Turpeinen, A.; Saraste, A.; Tribouilloy, C.; Biere, L.; Audonnet, M.; Bardet, H.; Marechaux, S.; Habib, G.; Thuny, F.; Monin, J.L.; Donal, E.; Gervais, R.; Bauer, F.; Attias, D.; Daudin, M.; Bernard, A.; Kostovska, E.S.; Radovikj, M.G.; Scholtz, W.; Nickenig, G.; Rassaf, T.; Lehnert, K.; Er, F.; Schulze, P.C.; Akin, Ibrahim; Maier, L.S.; Ince, H.; Vorpahl, M.; Sigusch, H.; Rahman Haley, S.L.; Kanakakis, I.; Katsaros, A.; Spargias, K.; Lampropoulos, K.; Bellos, V.; Papafaklis, M.; Makris, A.; Kamperidis, V.; Ninios, V.; Sachpekidis, V.; Poulimenos, L.; Borsányi, T.; Jarai, Z.; Zsáry, A.; Bajraktari, G.; Sime, I.; Erglis, A.; Rancane, G.; Mizariene, V.; Radauskaitė, G.; Demarco, D.C.; Mizia-Stec, K.; Szymanski, P.; Joao, I.; Antunes, N.; Bento, D.; Cardoso, G.; Galrinho, A.; Sousa, C.; Cabral, S.; Silva Carvalho, Sofia; Almeida, I.; Pop, C.; Tint, D.; Popescu, B.A.; Popescu, A.; Grigorica, L.; Arsenescu-Georgescu, C.; Usurelu, C.; Ionac, A.; Petris, A.O.; Kozmin, D.; Kulumbegov, O.; Spiropulos, N.; Boldyrev, S.; Zotov, A.; Irtyuga, O.; Kuznetsov, D.V.; Nikolic, N.M.; Stojsic-Milosavljevic, A.; Ruzicic, D.; Simkova, I.; Valocik, G.; Studencan, M.; Moral, S.; Molina Mora, M.J.; de la Morena Valenzuela, G.; Gallego, I.M.; Mitroi, C.; Vela, T.A.; González-Gómez, A.; Jimenez, L.C.; Castro, N.; Santos, I.M.; Villegas, D.V.; Payá, R.; Esteban, E.; Iglesia-Carreno, C.; Iglesias, F.C.; Demirtas, A.O.; Taylan, G.; Gudul, N.E.; Mert, K.U.; Mert, G.O.; Dogan, S.M.; Arslan, Ş.; Sayar, N.; Yildirim, T.; Yesilay, A.; Sayin, M.R.; Karabag, T.; Universitat Autònoma de Barcelona
Publication Year: 2024
Collection: Universitat Autònoma de Barcelona: Dipòsit Digital de Documents de la UAB
Subject Terms: Sex differences; Valvular heart disease
Description: Background and Aims To assess sex differences in disease characteristics and treatment of patients with severe native valvular heart disease (VHD) included in the VHD II EURObservational Research Programme. Methods A total of 5219 patients were enrolled in 208 European and North African centres and followed for 6 months [41.2% aortic stenosis (AS), 5.3% aortic regurgitation (AR), 4.5% mitral stenosis (MS), 21.3% mitral regurgitation (MR), 2.7% isolated right-sided VHD, 24.9% multiple left-sided VHD]. Indications for intervention were considered concordant if corresponding to class I recommendations specified in the 2012 ESC or 2014 AHA/ACC VHD guidelines. Results Overall, women were older, more symptomatic, and presented with a higher EuroSCORE II. Bicuspid aortic valve and AR were more prevalent among men while mitral disease, concomitant tricuspid regurgitation (TR), and AS above age 65 were more prevalent among women. On multivariable regression analysis, concordance with recommended treatment was significantly poorer in women with MS and primary MR (both P
Document Type: article in journal/newspaper
File Description: application/pdf
Language: English
ISSN: 15229645
Relation: European heart journal; Vol. 45 Núm. 37 (january 2024), p. 3818-3833; https://ddd.uab.cat/record/317415; urn:10.1093/eurheartj/ehae523; urn:oai:ddd.uab.cat:317415; urn:scopus_id:85205802991; urn:articleid:15229645v45n37p3818; urn:pmid:39212374; urn:pmcid:PMC11452747; urn:oai:pubmedcentral.nih.gov:11452747
Availability: https://ddd.uab.cat/record/317415
Rights: open access ; Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original. ; https://creativecommons.org/licenses/by/4.0/
Accession Number: edsbas.C5277647
Database: BASE