| Title: |
Multicenter precision of cortical and trabecular bone quality measures assessed by high‐resolution peripheral quantitative computed tomography |
| Authors: |
Burghardt, Andrew J; Pialat, Jean‐Baptiste; Kazakia, Galateia J; Boutroy, Stephanie; Engelke, Klaus; Patsch, Janina M; Valentinitsch, Alexander; Liu, Danmei; Szabo, Eva; Bogado, Cesar E; Zanchetta, Maria Belen; McKay, Heather A; Shane, Elizabeth; Boyd, Steven K; Bouxsein, Mary L; Chapurlat, Roland; Khosla, Sundeep; Majumdar, Sharmila |
| Source: |
Journal of Bone and Mineral Research, vol 28, iss 3 |
| Publisher Information: |
eScholarship, University of California |
| Publication Year: |
2013 |
| Collection: |
University of California: eScholarship |
| Subject Terms: |
32 Biomedical and Clinical Sciences (for-2020); 3202 Clinical Sciences (for-2020); Clinical Research (rcdc); Prevention (rcdc); Bioengineering (rcdc); Biomedical Imaging (rcdc); Osteoporosis (rcdc); 3 Good Health and Well Being (sdg); Aged (mesh); Aged; 80 and over (mesh); Bone and Bones (mesh); Feasibility Studies (mesh); Female (mesh); Humans (mesh); Male (mesh); Middle Aged (mesh); Reproducibility of Results (mesh); Tomography; X-Ray Computed (mesh); HR-PQCT; OSTEOPOROSIS; PRECISION; BONE; MICROSTRUCTURE; BONE STRENGTH; MULTICENTER STUDIES |
| Subject Geographic: |
524 - 536 |
| Description: |
High-resolution peripheral quantitative computed tomography (HR-pQCT) has recently been introduced as a clinical research tool for in vivo assessment of bone quality. The utility of this technology to address important skeletal health questions requires translation to standardized multicenter data pools. Our goal was to evaluate the feasibility of pooling data in multicenter HR-pQCT imaging trials. Reproducibility imaging experiments were performed using structure and composition-realistic phantoms constructed from cadaveric radii. Single-center precision was determined by repeat scanning over short-term ( |
| Document Type: |
article in journal/newspaper |
| File Description: |
application/pdf |
| Language: |
unknown |
| Relation: |
qt9877z5j5; https://escholarship.org/uc/item/9877z5j5; https://escholarship.org/content/qt9877z5j5/qt9877z5j5.pdf |
| DOI: |
10.1002/jbmr.1795 |
| Availability: |
https://escholarship.org/uc/item/9877z5j5; https://escholarship.org/content/qt9877z5j5/qt9877z5j5.pdf; https://doi.org/10.1002/jbmr.1795 |
| Rights: |
public |
| Accession Number: |
edsbas.C605B68E |
| Database: |
BASE |