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A Cross Sectional Study to Evaluate the Association between Hypothyroidism and Cholelithiasis

Title: A Cross Sectional Study to Evaluate the Association between Hypothyroidism and Cholelithiasis
Authors: Kanhaiya Nayak Bhagel; Aryan Kanwarinder Singh; Lokesh Singh; Vishal Shammi; Mathura Prasad Agarwal
Publisher Information: International Journal of Toxicological and Pharmacological Research
Publication Year: 2023
Collection: Zenodo
Subject Terms: Hypothyroidism; Euthyroidism; Thyroidism; Cholelithiasis; Gall stone
Description: Introduction: About 10 to 15% of adults suffer from cholelithiasis, a common illness of the gall bladder. Asymptomatic cholelithiasis patients make up more than 80% of the population. Gall stone production is thought to be a result of hypothyroidism, an endocrine condition, hyperlipidemia, and motility issues affecting the bile duct and sphincter of Oddi. Our study’s goal is to find out how common hypothyroidism is among cholelithiasis patients admitted to tertiary care facilities. Method: This descriptive cross-sectional study was carried out from May 2018 to April 2019 at the Department of Surgery, Pacific Institute of Medical Sciences, Udaipur, Rajasthan. The sample size was 50, and the sampling method was consecutive non-probability sampling. The study comprised all patients with cholelithiasis diagnosed by ultrasonography, ranging in age from 20 to 70. Each piece of information, including age, gender, height, weight, BMI, and hypothyroidism, was entered into a pre-made proforma and was analysed. For numerical variables, mean and standard deviation were computed, and for qualitative variables, frequencies and percentages. A t-test was done and p-value of 0.05 was considered significant. Result: Age, height, weight, and BMI had mean values of 41.66 13, 165.15 11, 35, 68.17 11, 95, and 25.69 7.19, respectively. 47.1% of the 174 individuals with cholelithiasis belonged to the 41–50 age group. 14.4% of the patients had hypothyroidism, mostly in women. Twenty (20.6%) of the 97 female patients and five (6.5%) of the 77 male patients both had hypothyroidism. Both males and females had statistically significant hypothyroidism. Conclusion: This study looked into the connection between cholelithiasis and hypothyroidism. It was determined that female, obese, and elderly patients had a higher incidence of hypothyroidism. In contrast to all other variables, the gender distribution of the hypothyroidism in cholelithiasis patients was statistically significant. ; Introduction: About 10 to 15% of adults suffer from ...
Document Type: article in journal/newspaper
Language: English
ISSN: 0975-5160
Relation: https://zenodo.org/records/11303172; oai:zenodo.org:11303172; http://impactfactor.org/PDF/IJTPR/13/IJTPR,Vol13,Issue1,Article8.pdf; https://doi.org/10.5281/zenodo.11303172
DOI: 10.5281/zenodo.11303172
Availability: https://doi.org/10.5281/zenodo.11303172; https://zenodo.org/records/11303172; http://impactfactor.org/PDF/IJTPR/13/IJTPR,Vol13,Issue1,Article8.pdf
Rights: Creative Commons Attribution 4.0 International ; cc-by-4.0 ; https://creativecommons.org/licenses/by/4.0/legalcode
Accession Number: edsbas.C707C47C
Database: BASE