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20-Year Risks of Breast-Cancer Recurrence after Stopping Endocrine Therapy at 5 Years

Title:	20-Year Risks of Breast-Cancer Recurrence after Stopping Endocrine Therapy at 5 Years
Authors:	Pan H; Gray R; Braybrooke J; Davies C; Taylor C; Mcgale P; Peto R; Pritchard Ki; Bergh J; Dowsett M; Hayes Df; Albain K; Anderson S; Arriagada R; Barlow W; Bartlett J; Bergsten‐nordström E; Bliss J; Boccardo F; Bradley R; Brain E; Cameron D; Clarke M; Coates A; Coleman R; Correa C; Costantino J; Cuzick J; Davidson N; Dodwell D; Di Leo A; Ewertz M; Forbes J; Gelber R; Gnant M; Goldhirsch A; Goodwin P; Hill C; Ingle J; Jagsi R; Janni W; Loibl S; Mackinnon E; Martin M; Mukai H; Norton L; Ohashi Y; Paik S; Perez E; Piccart M; Pierce L; Poortmans P; Raina V; Ravdin P; Regan M; Robertson J; Rutgers E; Slamon D; Sparano J; Swain S; Tutt A; Viale G; Von Minckwitz G; Wang X; Whelan T; Wilcken N; Winer E; Wolmark N; Wood W; Zambetti M; Alberro Ja; Ballester B; Deulofeu P; Fábregas R; Fraile M; Gubern Jm; Janer J; Moral A; De Pablo Jl; Peñalva G; Puig P; Ramos M; Rojo R; Santesteban P; Serra C; Solà M; Solarnau L; Solsona J; Veloso E; Vidal S; Abe O; Abe R; Enomoto K; Kikuchi K; Koyama H; Masuda H; Nomura Y; Sakai K; Sugimachi K; Toi M; Tominaga T; Uchino J; Yoshida M; Haybittle Jl; Leonard Cf; Calais G; Garaud P; Collett V; Delmestri A; Sayer J; Harvey Vj; Holdaway Im; Kay Rg; Mason Bh; Forbes Jf; Balic M; Bartsch R; Fesl C; Fitzal F; Fohler H; Greil R; Jakesz R; Marth C; Mlineritsch B; Pfeiler G; Singer Cf; Steger Gg; Stöger H; Canney P; Yosef Hma; Focan C; Peek U; Oates Gd; Powell J; Durand M; Mauriac L; Dolci S; Larsimont D; Nogaret Jm; Philippson C; Piccart Mj; Masood Mb; Parker D; Price Jj; Lindsay Ma; Mackey J; Hupperets Psgj; Bates T; Blamey Rw; Chetty U; Ellis Io; Mallon E; Morgan Dal; Patnick J; Pinder S; Lohrisch C; Nichol A; Bramwell Vh; Chen Be; Gelmon K; Goss Pe; Levine Mn; Parulekar W; Pater Jl; Shepherd Le; Tu D; Berry D; Broadwater G; Cirrincione C; Muss H; Weiss Rb; Abu‐zahra Ht; Portnoj Sm; Bowden S; Brookes C; Dunn J; Fernando I; Lee M; Poole C; Rea D; Spooner D; Barrett‐lee Pj; Mansel Re; Monypenny Ij; Gordon Nh; Davis Hl; Sestak I; Lehingue Y; Romestaing P; Dubois Jb; Delozier T; Griffon B; Mace Lesec’h J; De La Lande B; Mouret‐fourme E; Mustacchi G; Petruzelka L; Pribylova O; Owen Jr; Harbeck N; Jänicke F; Meisner C; Schmitt M; Thomssen C; Meier P; Shan Y; Shao Yf; Zhao Db; Chen Zm; Howell A; Swindell R; Boddington C; Burrett Ja; Cutter D; Duane F; Evans V; Gettins L; Godwin J; James S; Kerr A; Liu H; Mannu G; Mchugh T; Morris P; Read S; Wang Y; Wang Z; Albano J; De Oliveira Cf; Gervásio H; Gordilho J; Ejlertsen B; Jensen Mb; Johansen H; Mouridsen H; Palshof T; Gelman Rs; Harris Jr; Henderson C; Shapiro Cl; Christiansen P; Mouridsen Ht; Fehm T; Trampisch Hj; Dalesio O; De Vries Ege; Rodenhuis S; Van Tinteren H; Comis Rl; Davidson Ne; Robert N; Sledge G; Solin Lj; Sparano Ja; Tormey Dc; Dixon Jm; Forrest P; Jack W; Kunkler I; Rossbach J; Klijn Jgm; Treurniet‐donker Ad; Van Putten Wlj; Rotmensz N; Veronesi U; Bartelink H; Bijker N; Bogaerts J; Cardoso F; Cufer T; Julien Jp; Van De Velde Cjh; Cunningham Mp; Brufsky Am; Coleman Re; Llombart Ha; 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Kilburn L; Yarnold Jr; Benraadt J; Kooi M; Van De Velde Ao; Van Dongen Ja; Vermorken Jb; Castiglione M; Colleoni M; Collins J; Gelber Rd; Lindtner J; Price Kn; Regan Mm; Rudenstam Cm; Senn Hj; Thuerlimann B; Bliss Jm; Chilvers Ced; Coombes Rc; Hall E; Marty M; Buyse M; Possinger K; Schmid P; Wallwiener D; Bighin C; Bruzzi P; Del Mastro L; Dozin B; Pastorino S; Pronzato P; Sertoli Mr; Foster L; George Wd; Stewart Hj; Stroner P; Borovik R; Hayat H; Inbar Mj; Peretz T; Robinson E; Camerini T; Formelli F; Martelli G; Di Mauro Mg; Perrone F; Amadori D; Martoni A; Pannuti F; Camisa R; Musolino A; Passalacqua R; Iwata H; Shien T; Ikeda T; Inokuchi K; Sawa K; Sonoo H; Sadoon M; Tulusan Ah; Kohno N; Miyashita M; Takao S; Ahn Jh; Jung Kh; Korzeniowski S; Skolyszewski J; Ogawa M; Yamashita J; Bastiaannet E; Liefers Gj; Christiaens R; Neven P; Paridaens R; Van Den Bogaert W; Braun S; Martin P; Romain S; Janauer M; Seifert M; Sevelda P; Zielinski Cc; Hakes T; Hudis Ca; Wittes R; Giokas G; Kondylis D; Lissaios B; De La Huerta R; Sainz Mg; Ro J; Camphausen K; Danforth D; Lichter A; Lippman M; Smart D; Steinberg S; D’amico C; Lioce M; Paradiso A; Ohno S; Bass G; Brown A; Bryant J; Dignam J; Fisher B; Geyer C; Mamounas Ep; Redmond C; Wickerham L; Aihara T; Hozumi Y; Baum M; Jackson Im; Palmer Mk; Ingle Jn; Suman Vj; Bengtsson No; Emdin S; Jonsson H; Venturini M; Lythgoe Jp; Kissin M; Erikstein B; Hannisdal E; Jacobsen Ab; Reinertsen Kv; Varhaug Je; Gundersen S; Hauer‐jensen M; Høst H; Nissen‐meyer R; Mitchell Ak; Robertson Jfr; Ueo H; Di Palma M; Mathé G; Misset Jl; Levine M; Morimoto K; Takatsuka Y; Crossley E; Harris A; Talbot D; Taylor M; Cocconi G; Di Blasio B; Ivanov V; Paltuev R; Semiglazov V; Brockschmidt J; Cooper Mr; Falkson Ci; Hadji P; A’hern R; Makris A; Parton M; Pennert K; Powles Tj; Smith Ie; Gazet Jc; Browne L; Graham P; Corcoran N; Clack G; Van Poznak C; Deshpande N; Di Martino L; Douglas P; Lindtner A; Notter G; Bryant Ajs; Ewing Gh; Firth La; Krushen‐kosloski Jl; Anderson H; 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Ahlgren J; Garmo H; Holmberg L; Liljegren G; Lindman H; Wärnberg F; Asmar L; Jones Se; Aft R; Gluz O; Liedtke C; Nitz U; Litton A; Wallgren A; Karlsson P; Linderholm Bk; Chlebowski Rt; Caffier H.
Contributors:	Pan, H; Gray, R; Braybrooke, J; Davies, C; Taylor, C; Mcgale, P; Peto, R; Pritchard, Ki; Bergh, J; Dowsett, M; Hayes, Df; Albain, K; Anderson, S; Arriagada, R; Barlow, W; Bartlett, J; Bergsten‐nordström, E; Bliss, J; Boccardo, F; Bradley, R; Brain, E; Cameron, D; Clarke, M; Coates, A; Coleman, R; Correa, C; Costantino, J; Cuzick, J; Davidson, N; Dodwell, D; Di Leo, A; Ewertz, M; Forbes, J; Gelber, R; Gnant, M; Goldhirsch, A; Goodwin, P; Hill, C; Ingle, J; Jagsi, R; Janni, W; Loibl, S; Mackinnon, E; Martin, M; Mukai, H; Norton, L; Ohashi, Y; Paik, S; Perez, E; Piccart, M; Pierce, L; Poortmans, P; Raina, V; Ravdin, P; Regan, M; Robertson, J; Rutgers, E; Slamon, D; Sparano, J; Swain, S; Tutt, A; Viale, G; Von Minckwitz, G; Wang, X; Whelan, T; Wilcken, N; Winer, E; Wolmark, N; Wood, W; Zambetti, M; Alberro, Ja; Ballester, B; Deulofeu, P; Fábregas, R; Fraile, M; Gubern, Jm; Janer, J; Moral, A; De Pablo, Jl; Peñalva, G; Puig, P; Ramos, M; Rojo, R; Santesteban, P; Serra, C; Solà, M; Solarnau, L; Solsona, J; Veloso, E; Vidal, S; Abe, O; Abe, R; Enomoto, K; Kikuchi, K; Koyama, H; Masuda, H; Nomura, Y; Sakai, K; Sugimachi, K; Toi, M
Publisher Information:	Massachusetts Medical Society; USA; Waltham, MA
Publication Year:	2017
Collection:	Università degli Studi di Genova: CINECA IRIS
Description:	The administration of endocrine therapy for 5 years substantially reduces recurrence rates during and after treatment in women with early-stage, estrogen-receptor (ER)-positive breast cancer. Extending such therapy beyond 5 years offers further protection but has additional side effects. Obtaining data on the absolute risk of subsequent distant recurrence if therapy stops at 5 years could help determine whether to extend treatment.
Document Type:	article in journal/newspaper
File Description:	ELETTRONICO
Language:	English
Relation:	info:eu-repo/semantics/altIdentifier/pmid/29117498; info:eu-repo/semantics/altIdentifier/wos/WOS:000414845700008; volume:377; firstpage:1836; lastpage:1846; numberofpages:11; journal:NEW ENGLAND JOURNAL OF MEDICINE; https://hdl.handle.net/11567/881777
DOI:	10.1056/NEJMoa1701830
Availability:	https://hdl.handle.net/11567/881777; https://doi.org/10.1056/NEJMoa1701830
Rights:	info:eu-repo/semantics/openAccess
Accession Number:	edsbas.C80EC88D
Database:	BASE