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In-flow photooxygenation of aminothienopyridinones generates iminopyridinedione PTP4A3 phosphatase inhibitors

Title: In-flow photooxygenation of aminothienopyridinones generates iminopyridinedione PTP4A3 phosphatase inhibitors
Authors: Tasker, Nikhil R.; Rastelli, Ettore J.; Blanco, Isabella K.; Burnett, James C.; Sharlow, Elizabeth R.; Lazo, John S.; Wipf, Peter
Contributors: U.S. Department of Defense
Source: Organic & Biomolecular Chemistry ; volume 17, issue 9, page 2448-2466 ; ISSN 1477-0520 1477-0539
Publisher Information: Royal Society of Chemistry (RSC)
Publication Year: 2019
Description: A continuous flow photooxygenation of 7-aminothieno[3,2- c ]pyridin-4(5 H )-ones produces potent in vitro inhibitors of the cancer-associated protein tyrosine phosphatase PTP4A3.
Document Type: article in journal/newspaper
Language: English
DOI: 10.1039/c9ob00025a
Availability: https://doi.org/10.1039/c9ob00025a; http://pubs.rsc.org/en/content/articlepdf/2019/OB/C9OB00025A
Rights: http://rsc.li/journals-terms-of-use#chorus
Accession Number: edsbas.CAD39838
Database: BASE