| Title: |
Vericiguat for patients with heart failure and reduced ejection fraction across the risk spectrum: an individual participant data analysis of the VICTORIA and VICTOR trials |
| Authors: |
Zannad, Faiez; O'Connor, Christopher, M; Butler, Javed; Mcmullan, Ciaran, J; Anstrom, Kevin, J; Barash, Irina; Bonaca, Marc, P; Borentain, Maria; Corda, Stefano; Gates, Davis; Ezekowitz, Justin, A; Hernandez, Adrian, F; Lam, Carolyn, S P; Lewis, Eldrin, F; Lindenfeld, Joann; Mentz, Robert, J; Ponikowski, Piotr; Reddy, Yogesh, N V; Rosano, Giuseppe, M C; Saldarriaga, Clara; Senni, Michele; Teixeira, Pedro, P; Udelson, James; Urbinati, Alessia; Vlajnic, Vanja; Voors, Adriaan, A; Xing, Aiwen; Patel, Mahesh, J; Armstrong, Paul, W; Pieske, Burkert; Koglin, Joerg; Roessig, Lothar; Reay, Kris; Soulard, Lisa; Temple, Tracy; Westerhout, Cynthia; Hamlin, Constance; Lovett, Rhonda; Ryan, Nicholas; Blaustein, Robert; Golm, Gregory; Jia, Gang; Kent, Christi; de Klerk, Jaco; Salerno, Christina; Broeker-Zweering, Sabine; Nkulikiyinka, Richard; Wu, Elaine; Mueller, Katharina; Pieske-Kraigher, Elisabeth; Kropf, Martin; Kim, Raymond, J; Parker, Michele; Kelle, Sebastian; Schulz-Menger, Jeanette; Defilippi, Christopher; Bell, Rachel; Shah, Palak; Shaw, Peter; Lassman, Michael; Kramer, Frank; Christenson, Robert; Mark, Daniel; Davidson-Ray, Linda; Bahit, M. Cecilia; Kaye, David, M; Bonderman, Diana; Pouleur, Anne-Catherine; Bocchi, Edimar, A; Lanas, Fernando; Zhang, Jian; Melenovský, Vojtěch; Refsgaard, Jens; Lassus, Johan; Cohen-Solal, Alain; Edelmann, Frank; Tziakas, Dimitrios, N; Arango Benecke, Juan Luis; Siu, David; Noori, Ebrahim; Mcdonald, Kenneth; Lewis, Basil, S; Emdin, Michele; Tsutsui, Hiroyuki; Zainal Abidin, Imran; Escobedo, Jorge; Mosterd, Arend; Troughton, Richard, W; Atar, Dan; Godoy Palomino, Armando Lionel; Reyes, Eugenio, B; Vazquez-Tanus, Jose, B; Cho, Myeong-Chan; Lopatin, Yury; Sim, David; Sliwa-Hähnle, Karen; López-Sendón, José; Lund, Lars, H; Chiang, Chern-En; Oto, M. Ali; Cowie, Martin; Givertz, Michael, M; Piña, Ileana, L; K. Sweitzer, Nancy; McMurray, John J.V.; Granger, Christopher, B; Cook, Thomas, D; Francis, Gary, S; Swedberg, Karl; Hedlin, Haley; Felker, G. Michael; Jones, W. Schuyler; Alexander, Karen, P; Al-Khatib, Sana, M; Dombrowski, Keith, E; Harrison, Robert, W; Lopes, Renato, D; Mathews, Robin; Povsic, Thomas, J; Roe, Matthew, T; Vemulapalli, Sreekanth; Perna, Eduardo Roque; Galarza Salazan, Maria; Mackinnon, Ignacio; Eden, Florencia; Cartasegna, Luis; Novas, Viviana; Luquez, Hugo, A; Cenci, Ana; Hominal, Miguel Angel; Bianchini, Maria Veronica; Ahuad Guerrero, Rodolfo Andres; Alvarez D Amelio, Andrea; Poy, Carlos Alberto; Poy, Maria; Majul, Claudio, R; Currao, Cecilia; Vottero, Ezequiel Hector; Perrin, Mariana; Zaidman, Cesar Javier; Espinosa, Maria Vanesa; Zapata, Gerardo; Arias, Luciana; Sassone, Sonia Angelica; Tonelli, Lucas; Chirino Navarta, Daniel Agustin; Mangini, Maria; Cuadrado, Jesus; Bordoni, Paula; Carter, Kaye; Amerena, John; Shanahan, Toni; Mckenzie, Scott; Stibijl, Kathryn; de Pasquale, Carmine; Wollaston, Fiona; Colquhoun, David Martin; Ferreira-Jardim, Antonio; Chan, Alicia; Dymmott, Greer; Mcquillan, Brendan; Mohammadi, Katayun; Cross, David; Jeffrey, Judy; Sindone, Andrew; Gebran, Magdalena; Shah, Amit; Tulloch, Gill; William, Maged; Conway, Bets; Wong, James; North, Donna; von Lewinski, Dirk; Brandner, Karin; Hoppe, Uta; Kopp, Kristen; Mascherbauer, Regina Steringer; Steinkellner, Claudia; Binder, Christina; Adlbrecht, Christopher; Leitgeb, Maria; Sinnaeve, Florence; Dupont, Matthias; Claes, Carola; de Ceuninck, Michel; Vancayseele, Els; Timmermans, Philippe; van Genechten, Gregory; Troisfontaines, Pierre; Massoz, Mireille; Huynh, Thao Thanh; Boudreault, Caroline; Sabbah, Eric; Chausse, Isabelle; Bourgeois, Ronald Leonard; Boyd, Karen; Heffernan, Michael; Birch, Marie; Parent, Marie-Claude; Brown, Helene; Pandey, A. Shekhar; Ballivian, Tatiana; Giannetti, Nadia; Sahebjamei, Reza; Vizel, Saul; Fox, Beverley; Rupka, Dennis Wayne; Thiessen, Sandi; Constance, Christian; Gauthier, Marie-France; Kushnerik, Quentin; Schaffer, Allan; Janz, Wendy; Chan, Michael; Knight, Jennifer; Lepage, Serge; Soucy, Daniel; Parker, John, D; Hsu, Elaine; Mielniczuk, Lisa; Moga, Ermina; Coutu, Benoit; Fleury, Julie; Macdonald, Paul; Hines, Kathleen; Delgado, Diego; Nugaeva, Natalia; Sia, Ying; Roy, Isabelle; Laflamme, David; Simard, Christel; Gosselin, Gilbert; Drouin, Katia; Clarke, Brian; Ronak, Kimberley; Saulnier, Denis; Cote, Melissa; Sussex, Bruce Alexander; Druken, Bernadette; Rajda, Miroslaw; Falkenham, Jayne; Mukherjee, Ashok; Bozek, Beverly; Ling Moe, Gordon Willy Pak; Fernando, Carlos; Bergeron, Sebastien; Tremblay, Hugo; Shibata, Marcelo Coelho; Woloschuk, Bonnie; Manyari, Dante; Cleveland, Tracy; Nigro, Frank; Forsyth, Crystal; Roy, Annie; Bolduc, Helene; Dion, Danielle; Gilbert, Nancy; Cha, James, Y; Otis, Judy; Barabas, Melinda; Chartrand, Marie-Josee; Assef, Victor; Eikhof, Andrea; Novajas Balboa, Manuel; Aravena Vasquez, Carla Belen; Prieto Dominguez, Juan Carlos; Noriega, Viviana; Yovaniniz, Patricio; Grandon, Marcela; Hidalgo, Jessica; Zhang, Yuhui; Dong, Jing; Dai, Haiying; Xiao, Ying; Jiang, Tingbo; Shi, Lin; Chen, Jiyan; He, Peiyu; Peng, Daoquan; Qing, Fangmei; Xu, Biao; Wang, Ruihong; Gu, Xiang; Wang, Min; Yao, Zhuhua; Chen, Ying; Miao, Peizhi; Chen, Zhenfei; Li, Hui; Huang, Dongyan; Yang, Qing; Yu, Xuefang; Shen, Aidong; Zhang, Xin; Liu, Xiaohui; Lv, Qiang; Dong, Yugang; Liu, Dan; Wang, Jingfeng; Ouyang, Huijun; Tang, Chengchun; Chen, Yong; Gong, Hui; Teng, Dandan; Yan, Jing; Xu, Linying; Jiang, Weihong; Zhou, Xiaowei; Fu, Guosheng; Zheng, Ying; Zhang, Shuyang; Xu, Lihong; Yang, Zhenyu; Wu, Chenying; Han, Xiumin; Wang, Yuxia; Yu, Jing; Wang, Qiongying; Wang, Lihong; Zheng, Lili; Jin, Wei; Zhang, Nan; Zhang, Chuanhuan; Sun, Xiaojian; Yao, Yali; Lei, Peng; Zheng, Zhaofen; Wang, Junkui; Ma, Fengling; Long, Mingzhi; Wang, Sulan; Zhang, Hong; Guo, Mingmei; Chen, Manhua; Wang, Yayun; Li, Zhanquan; Duan, Ruili; Yuan, Zuyi; Li, Tiaotiao; Mei, Yibin; Ye, Linyan; Huang, Zhouqing; Zhang, Xingyuan; Liu, Wenling; Li, Lei; Zhao, Ruiping; Gong, Jie; Zhang, Dongqing; Zhu, Jiahui; Yang, Chengjian; Wang, Chunxia; Ji, Zheng; Xinpei, Gao; Mei, Xia; Liu, Mingyun; Garcia Amaya, Paula; Castano Osorio, Wilder; Dussan, Maria; Quiroz Diaz, Franklin Roberto; Prada, Yuleth; Jaramillo Munoz, Carlos Francisco; Zapata, Ana; Jaramillo, Monica; Bello, Solmara; Botero, Rodrigo; Salazar, Sandra; Lopez Pareja, Monica; Mora, Claudia; Jaramillo Gomez, Nicolas Ignacio; Garcia, Juan Camilo; Torres, Fabian; Moncada, Miguel Alfredo; Velez Gil, Laura; Torres, Jaime Andres; Lievano, Yolanda; Krausova, Miroslava; Malik, Jan; Hajsl, Martin; Mala, Katerina; Vojacek, Jan, F; Fridrichova, Jana; Malek, Filip; Rihova, Dana; Cech, Vladimir; Masarikova, Lenka; Machova, Vilma; Spinar, Jindrich; Macha, Jan; Nechvatal, Libor; Egstrup, Kenneth; Moltrup, Lene; Haastrup, Benedikte; Jespersen, Camilla; Nyvad, Ole; Tanggaard, Lene; Fog, Lars; Johansen, Pauline; Wiggers, Henrik; Serup-Hansen, Kristine; Due Lomholdt, Jens; Niemann, Kari; Nielsen, Olav Wendelboe; Stokholm, Elisa; Taskiran, Mustafa; Pedersen, Lotte Ring; Nyman, Kai; Sankari, Tiina; Ukkonen, Heikki; Vasankari, Tuija; Karesvuori, Sari; Vazquez Ibarra, Miguel; Gallouj, Karim; Lombart, Angelique; Damy, Thibaud; Karhoubi, Mounira; Galinier, Michel; Rosoli, Nathalie; Taldir, Guillaume; Vomscheid, Maelle; Tartiere, Jean-Michel; Genin, Charline; Salvat, Muriel; Pollet, Delphine; Citron, Bernard; Lamallem, Ouarda; Girerd, Nicolas; Poinsignon, Lydie; Jourda, Francois; Mougenot, Emmanuelle; Boughanmi, Hatem; Fodil, Hanane; Benhamou, Lionel; Harzi, Ghania; Störk, Stefan; Knoppe, Anja; Appel, Karl-Friedrich; Becker, Petra; Bauersachs, Johann; Geyer, Manuela; Schmidt, Ekkehard; Schmidt, Kristina; Strempel, Sophia; Beug, Daniel; Bruder, Michael; Jeserich, Michael; Rupprecht, Mariana; Haake, Hendrik; Krug-Hoeren, Bianca; Hagenow, Andreas; Kuntzsch, Anja; Vojvodic-Mayer, Mirjana; Lux, Ronny; Horacek, Thomas; Pluemer-Schmidt, Manuela; Knapp, Markus; Suepple-Poch, Edith; Mitrovic, Veselin; Peil, Annerose; Rosenkranz, Stephan; Roelle-Hoehne, Susanne; Bekeredjian, Raffi; Probst, Ina; Tuleta, Izabela; Lauterborn, Marjo; Winkelmann, Bernhard; Tenbusch, Linda; Zeh, Wolfgang; Eble, Sandra; Kessler, Mirjam; Dichristin, Uta; Maier, Lars; Kellner, Esther; Chalikias, Georgios; Triposkiadis, Filippos; Papamichalis, Michalis; Parissis, John; Bistola, Vasiliki; Karvounis, Haralampos; Giannakoulas, Georgios; Tousoulis, Dimitrios; Chrysohoou, Christina; Naka, Katerina; Kotsia, Anna; Montenegro Valdovinos, Pablo Carlos; Aguilar, Mayra; Gonzalez Orellana, Ronaldo, A; Meléndez, Ester; Garcia de Krumbach, Lissette; Rodríguez, Edgar Rolando; Barrera, Karla; Aguilar Vásquez, Mynor Adolfo; Siu, Chung Wah David; Ho, Venus San Lui; Lee, Pui-Wai Alex; Wang, Xue Ting; Fan, Katherine; Tam, Eva; Mihaly, Gyongyver Ibolya; Kalina, Akos; Szabo, Anita; Kancz, Sandor; Hentzel, Istvanne; Lakatos, Ferenc; Toth, Krisztina; Merkely, Bela; Dzsida, Laura; Palinkas, Attila; Toth, Szilvia Rostasne; Svab, Marianna; Bugarin-Horvath, Balazs; Kirschner, Robert, J; Toth Karolyne, Rozsa; Maher, Joanne; Murphy, Ross; Hall, Mary; Mahon, Niall; Gilroy, Elaine; Mcadam, Brendan; Farrell, David; O Neill, James; Blaine, Ciara; Atar, Shaul; Nadaf, Rita; Hayek, Tony; Hassan, Mira; Zarachovsky, Lena; Shochat, Michael; Aloni, Ilana; Assali, Abid; Tsirulnikov, Elena; Kinany, Wadi; Etkin, Janna; Ben Gal, Tuvia; Even Nir, Hadas; Arbel, Yaron; Shani, Adi Katalan; Mazen, Elias; Ron Avraham, Gilat; Goland, Sorel; Suzdalnizki, Anastasia; Halabi, Majdi; Portnov, Ilana; Hasin, Tal; Rojansky, Astrid; Jabara, Rafat; Levin, Galina; Katz, Amos; Tubul, Orna; Moravsky, Gil; Lapidus, Ira; Ambrosio, Marilisa; Passino, Claudio; Gabutti, Alessandra; Scelsi, Laura; Vullo, Eleonora; Midi, Paolo; Felici, Anna; Fucili, Alessandro; Sarcone, Maria; Nodari, Savina; Lupi, Laura; Spagnuolo, Vitaliano; Volterrani, Maurizio; Morsella, Valentina; Sarzi Braga, Simona; Vaninetti, Raffaella; Agostoni, Piergiuseppe; Salvioni, Elisabetta; Taddei, Stefano; Bruno, Rosa Maria; Parati, Gianfranco; Munforti, Carlotta; Lauciello, Rosanna; Coiro, Stefano; Mortara, Andrea; Mazzetti, Simone; Sinagra, Gianfranco; Ramani, Federica; Gualco, Alessandra; Cattaneo, Simona; Argiolas, Giuseppe; Masala, Wanda; Cosmi, Franco; Mariottoni, Beatrice; Nakamura, Akihiro; Futono, Kazumi; Komaru, Tatsuya; Endo, Tomoko; Fukuzawa, Shigeru; Nakamura, Yumi; Okumura, Yasuo; Sato, Haruka; Tabata, Hirotsugu; Saino, Mizuki; Ikeda, Takanori; Kaminishi, Reiko; Ebato, Mio; Fukatsu, Akiko; Aoyama, Takahiko; Kitani, Chihiro; Sakamoto, Hiroki; Amano, Kaori; Saeki, Tomoaki; Shimano, Kayo; Kada, Kenji; Tsuzuki, Yoko; Hashimoto, Tetsuo; Okamoto, Madoka; Fujii, Kenshi; Tsujimoto, Mari; Ichinohe, Tahei; Okabe, Saori; Hirooka, Keiji; Senshu, Yuna; Ohta, Tetsuro; Hayashi, Tomomi; Kawai, Yusuke; Horio, Juri; Takaishi, Atsushi; Nakamura, Mikiko; Takatsu, Hiroyuki; Shiota, Tomoko; Maemura, Koji; Nishida, Momoyo; Shibata, Yoshisato; Nagashima, Kaori; Shibasaki, Taro; Takahashi, Nobue; Iseki, Harukazu; Otsuki, Kenichi; Matsuoka, Shunzo; Motoda, Kentaro; Higuchi, Yoshiharu; Hayasaki, Hiromi; Manita, Mamoru; Ito, Riyo; Suzuki, Masahiro; Fumikura, Kaori; Iwata, Hiroshi; Kinjo, Kaori; Takimoto, Eiki; Omori, Yuki; Yumoto, Kazuhiko; Yoshizawa, Jun; Izumi, Chisato; Hirase, Kanae; Higashiue, Shinichi; Ishibaba, Ayaka; Higashino, Yorihiko; Matsumura, Takuro; Iida, Hiroshi; Kowa, Kaya; Koga, Tokushi; Hatakeda, Tomomi; Atsuchi, Nobuhiko; Migita, Kana; Momiyama, Yukihiko; Fukuda, Yusuke; Fukue, Masataka; Uchida, Kouji; Saito, Katsumi; Iida, Sakiko; Fukamizu, Seiji; Harada, Junko; Takei, Yasuyoshi; Takano, Saori; Hata, Yoshiki; Sato, Arisa; Shimura, Yumi; Hirata, Shinko; Namiki, Atsuo; Ishida, Noriko; Michishita, Ichiro; Ishimoto, Tomomi; Usuda, Kazuo; Oomura, Akiko; Kinugawa, Koichiro; Sasaki, Rumi; Matsubara, Takao; Kidani, Hiromi; Awaji, Yoshifumi; Kaneno, Yoko; Yamashita, Kentaro; Suzuki, Masami; Fujita, Hiroshi; Mashida, Aya; Yamada, Takahisa; Hirai, Shintaro; Ichikawa, Minoru; Muromaki, Takae; Ohtani, Tomohito; Yamaguchi, Sachiyo; Furukawa, Yutaka; Takata, Mika; Baden, Masato; Kawasaki, Futoshi; Tashiro, Hideki; Kita, Yuko; Taki, Mizuri; Suzuki, Kuniko; Nakama, Kenji; Oota, Chiaki; Hibi, Kiyoshi; Shiono, Mizuho; Matoba, Satoaki; Kimura, Natsuki; Takahashi, Akihiko; Fujino, Megumi; Ide, Tomomi; Tanaka, Chiharu; Ueda, Osamu; Shimojima, Rieko; Kuramochi, Takehiko; Ando, Michiko; Onaka, Haruhiko; Maeda, Anri; Higami, Tetsuya; Nishibe, Ikumi; Abe, Mitsunori; Matsugi, Megumi; Ako, Junya; Yamamura, Kimiko; Ueda, Tomoya; Itokazu, Yuki; Sumii, Kotaro; Ichii, Kano; Shimizu, Masatoshi; Irikura, Megumi; Shimizu, Shigeo; Ayabe, Misa; Matsubara, Taku; Kaneko, Satoko; Koizumi, Tomomi; Watanabe, Keiko; Sakagami, Satoru; Kumaki, Mariko; Suzuki, Atsushi; Kawano, Tomoe; Katayama, Yusuke; Nakamura, Hiroko; Taguchi, Isao; Araki, Yuko; Higa, Nobuyoshi; Oshiro, Yasuka; Yahikozawa, Kumiko; Anzai, Shiori; Nunohiro, Tatsuya; Nishi, Daichi; Osaki, Shuichi; Tanaka, Yoshiaki; Kaneko, Masayuki; Noguchi, Kimiko; Watanabe, Noriaki; Oishi, Toru; Fuse, Koichi; Baba, Yukari; Kim, Ga-Eun; Jeong, Jin-Ok; Choi, Young-Eun; Lee, Hae-Young; Hur, Eunjin; Kang, Seok-Min; Lee, Wonmi; Kim, Kye Hun; Song, Jiyeon; Yoo, Byung-Su; Shin, Seonmi; Shin, Mi Seung; Oh, Hei Won; Kim, Eung Ju; Park, Jinju; Choi, Dong-Ju; Yoon, Eun Ji; Yang, Dong Heon; Choi, Jihyeong; Choi, Jung-Hyun; Jeong, Hwayoung; Choi, Jin-Oh; Hyun, Seo Jin; Jo, Sang-Ho; Sujin, Lee; Jin, Dong Kyu; Jeon, Jiwon; Shin, Joon-Han; Na, Ji Sung; Kim, Dong-Soo; Oh, Eunryul; Ong, Tiong Kiam; Sulehan, Juriah; Che Hassan, Hamat Hamdi; Amni, Zati; Zainal Abidin, Siti Khairani; Ravinttiran, Kanaga Lakshimi; de los Rios Ibarra, Manuel Odin; Martinez Sanchez, Carlos Rodolfo; Ronquillo Ramirez, Diestefano; Salazar Gaytan, Abel; Gonzalez Sandoval, Carmen; Alcocer Gamba, Marco Antonio; Munoz Rosales, Wendy; Esturau Santalo, Ramon Miguel; Sanchez Mendoza, Yazmin; Mendez Machado, Gustavo Francisco; Hirata Avila, Haydea; Reyes Araiza, Raul; Ruiz Morales, Jaime; Escobedo de la Pena, Jorge; Villegas Lara, Beatriz; Lopez Rosas, Enrique; Meza Hernandez, Michelle; Chavez Michel, Jaime; Ruiz Rubio, Elena; Varela, Alberto; Hobé-Rap, Coriet; Lok, Dirk; Dommerholt, Rina; Swart, Henk; van Scheltinga, Catharina Terwisscha; van de Wal, Ruud; van Lieshout, Ilvy; van der Meer, Peter; Branderhorst, Anja; Werner, Henri Albert; van Ruijven-Mastenbroek, Ivonne; Meijs, Matthijs F.L.; Oldenhof, Linnea; den Hartog, Frank; Singerling, Margreeth; Troughton, Richard William; Rose, Stephanie; Hamilton, Fraser; Jacques, Sharon; Ferrier, Katherine; Kovacs, Jo-Anne; Lund, Mayanna; Pearce, Lynette; Doughty, Robert; Terbals, Mariska; Amir, Nezar; Hulbert, Cathy; Pemberton, James; Scott, Deborah; Nilsen, Dennis; Nilsen, Jorunn; Gullestad, Lars; Bjorklund, Elisabeth; Claussen, Hege; Keilegavlen, Havard; Faalun, Nina; Ruddox, Vidar; Pedersen, Annbjoerg; German Rodriguez Escudero, Aldo Edwin; Romero, Sonia; Orihuela, Boris; del Portal, Monica; Rodriguez, Victor Elias; Cabanillas Gallo, Nurys; Medina, Felix Alvaro; Rodriguez, Jeanneth; Lu Galarreta, Libia; Espejo, Jill; Matta, Milagros; Salvador, David Raymund K.; Cudiamat, Wendy Lynn; Reyes, Eugene; de Guzman, Susan; Sy, Rody; Silva, Claudette; Brillantes, Amelita; Alon-Alon, Amy; Iii, Gabriel Jocson; Cortez, Frances Joyce; Tirador, Louie, S; Gamboa, Charity Daine A.; Habaluyas, Ramoncito, S; Incognito, Mary Jane; Szachniewicz, Joanna; Nawrocka-Millward, Sylwia; Goch, Aleksander; Lugowski, Tomasz; Nessler, Jadwiga; Czubek, Urszula; Straburzynska Migaj, Ewa; Przepiora, Agnieszka; Pijanowski, Zbigniew; Pijanowska, Monika; Kasprzak, Jaroslaw; Mirek-Bryniarska, Ewa; Zareba, Wojciech; Musial, Wlodzimierz; Tycinska, Agnieszka; Miekus, Pawel; Przydatek, Justyna; Krysiak, Waldemar; Skorek, Edyta; Leszek, Przemyslaw; Polaska, Paula; Skonieczny, Grzegorz Krzysztof; Roliard, Monika; Wujkowski, Marek; Strupiechowski, Mariusz; Diago, Maria; Baez, Julio; Casanova-Jimenez, Lusdian; Zayas-Torres, Carlos, R; Duran, Aleja; Colon-Hernandez, Pedro, J; Carrasquillo, Merari; Rios Bonilla, Maria, L; Marcano, Magaly; Garcia-Gordo, Pedro; Navedo-Santos, Jessenia; Boldueva, Svetlana; Shvets, Natalia; Orlova, Natalia; Klepikova, Maria; Kastanayan, Alexander; Babaeva, Leily; Meray, Imad; Teterina, Marina; Shvarts, Yury; Konshina, Larisa; Yakushin, Sergey; Filippov, Evgeniy; Sayganov, Sergey; Nikolaev, Dmitry; Vishnevskiy, Alexander; Zykov, Vladislas; Solovev, Oleg; Nazarov, Dmitry; Bolshakova, Olga; Polunicheva, Ekaterina; Treshkur, Tatiana; Berngardt, Edvard; Nosov, Vladimir; Koroleva, Lubov; Kamalov, Gadel; Urazaeva, Liliya; Ilyukhin, Oleg; Morozov, Evgeny; David Sim, Kheng Leng; Lee, Yuen Yet; Lee, Shao Guang Sheldon; Tang, Xuan; Soon, Dinna Kar Nee; Lim, Boon Khim; Wong, Raymond Cc; Wong, Cher Yi; Loh, Seet Yoong; Cheng, Geok; Tan, Geraldine; Abelson, Mark Jonathan; King, Annusca; Bayat, Junaid; Badat, Katija; Ranjith, Naresh; Ramdas, Shavina; Nunkoo, Theema; Prozesky, Hans Walter; Naude, Christina; Fulat, Muhammed Ameen; Pretorius, Michelle; Ntsekhe, Mpiko; Mtana, Noloyiso; Klug, Eric, Q; Naidoo, Vaman; Pillay-Ramaya, Larisha; Phillips, Sharon; Makotoko, Ellen Makoali; Page, Andonia; Malahleha, Moelo; Pitsoane, Mosidi; Mediavilla Garcia, Guiomar; Gonzalez Juanatey, Jose Ramon; Seijas Amigo, Jose; Martínez-Sellés, Manuel; Sobrino González, Olga; González-Ferrer, Eduardo; González, Paz; Manito Lorite, Nicolas; Guerrero, Sonia; Farré López, Núria; Soler Ayat, Cristina; Gomez Doblas, Juan Jose; Robles, María; Núñez, Julio; Mollar Fernández, Anna; Gómez Bueno, Manuel; González Segovia, Ariadna; Hultman-Cadring, Ann; Pol, Tymon; Langoe, Annika; Hansen, Ole; Nake, Else; Danyi, Tamas; Kruse, Anna-Karin; Magnusson, Christer; Palo, Ninve; Fu, Michael; Fahlen, Kim; Bollano, Entela; Westlund, Ann-Christin; Hullin, Roger; Salzmann, Sandrine; Moccetti, Tiziano; Serra, Anna; Mueller, Christian; Flores, Dayana; Lin, I-Chen; Hwang, Juey-Jen; Chen, Yi-Chun; Chang, Wei-Ting; Su, Shu-Fen; Chao, Ting-Hsing; Tseng, Wen-Hui; Wu, Yen-Wen; Chen, Yung-Cheng; Liu, Ming-En; Chou, Vinny; Cavusoglu, Yuksel; Yilmaz, Mehmet Birhan; Sansoy, Vedat; Sahin, Tayfun; Sezer, Murat; Celik, Ahmet; Oto, Mehmet Ali; Tengiz, Istemihan; Reshotko, Oksana; Donets, Oleksandra; Rybachok, Yuliia; Sychov, Oleg; Romanova, Olena; Kulbachuk, Oleksandr; Klitsunova, Yuliia; Velichko, Natalia; Tomakh, Nataliia; Squire, Iain; Fisher, Judith; Bethell, Hugh; Howard, Emma; Barr, Craig Scott; Dean, Julie; Clark, Andrew; Bulemfu, Jeanne; Cooke, Justin; Whileman, Amanda; Davies, Ceri; Pheby, Jane; Mcdonagh, Theresa; Breeze, Jonathan; Wong, Kenneth; Fleming, Catherine; Amin, Jay; Cervoni, Theresa; Aslam, Shamaila; Burns, Dawn; Bank, Alan, J; Gernes, Nicole; Bedwell, Noel, W; Craig, Mary; Iteld, Bruce, J; Ocman, Brandy; Bhalla, Rajinder; Hicks, Teresa; Chu, A. Alan S.P.; Nguyen, Susan; Feldman, James; Peek, Madeline; George, Ferris; Baker, Christine; Gray, Wayne, L; Adair, Sherry; Jetty, Preetham; Key, Alyssa; Kazemi, Navid; Hollis, Suzette; Larned, Joshua; Ortiz, Mara-Li; Smith, Janet, L; Abell, Tina; Cadaret, Linda; Larew, Cynthia; Long, Robert; Hickey, Theresa; Mahal, Sharan, S; Yandamuri, Sivaradhika; Whellan, David, J; Schwegler, Daniel; Mccullough, Peter; Baker, Rebecca; Mcginty, John; Fry, Nancy; Pelzel, Jamie, M; Douvier, Ashley; Vilaro, Juan; Long, Sarah; Perlman, Richard; Hoopes, Donna; Podugu, Ramana; Smith, Kathleen; Rahko, Peter; Olsen, Karen, J; Ravichandran, Ashwin; Reilly, Bonnita; Sangrigoli, Renee; Schwarz, Linda; Greene, Trevor, O; Jackson, Cathy; Davis, Teleah; Spiller, Dennis; Ferrin, Smelda; Viswanath, Dilip, B; Manga, Sue; Xu, Zi Jian; Holmes-Rees, Deborah; Bittrick, Jon, M; Calhoun, Ericka; Ewald, Gregory Alan; Bult, Karen; Farr, Maryjane; Kim, Andrea; Forgosh, Les; Riestenberg-Smith, Joyce; Jaffrani, Naseem; Childers, Rebecca; Brinkley, Douglas Marshall; Carroll, Amanda; Mclean, Dalton, S; Pruitt, Hugh; Lewis, Greg; Cocca-Spofford, Diane; Snyder, Harvey, A; Pantuck, Louise; Teufel, Edward, J; Glasgow, Brenda; Donovan, Daniel, J; Alvarado-Garcia, Maria Magdalena; Dauber, Ira; Derbyshire, Susan; Zavaro, Suhail; Miller, Aolani; Sharkey, Kevin; Ferguson, Alanza; Adams, Kirkwood; Glotzer, Jana; Perez, Jose, A; Addington, Jodie; Bhatti, Zulfiquar; Burton, Carla; Melucci, Mike, B; Meier, Susan; Huber, Michael; Anazawa, Fujiko; Upshaw, Jenica; Carr, Katelyn; Holmberg, Mark Jeffrey; Rasmussen, Lois, S; Lucarella, Vanessa, J; Maloney, Kathleen; Sabatino, Kenneth, C; Everett, John; Kelley, Emily; Murthy, Sandhya; Camillo, Angeline; Sweitzer, Nancy; Schrag, Cindy; Carson, Peter, E; Gannuscio, Jacqueline; Lewis, Neil Pendril; Chafin, Krista; Miller, Alan Bruce; Richardson, Erin; Qayyum, Usman; Brown, Paige; Singal, Dinesh; Giunta, Danielle; Krishnamoorthy, Arun; Vallabh, Reema; Keller, Andrew, J; Burton, Stephanie; Adler, Alexander; Thompson, Dean; Stehlik, Josef; Hong, Jennifer; Luckasen, Gary, J; Kaczkowski, Scott; Old, Wayne; Bullivant, Melinda; Boehmer, John; Gardner, Kevin; Gupta, Dinesh, K; Davey, Tammy; Mehta, Hirsch; Ciezkowski, Gina; Hong, Michael; Hejna, Elizabeth; Guha, Ashrith; de Oliveira, Marcos; Haddad, Tariq; Overbeck, Deanna; Taheri, Hamid; Elie, Abbey; Dumitru, Ioana; Guedes, Ricardo; Heroux, Alain; Kartje, Carol; Zughaib, Marcel, E; Edillo, Candice; Link, Chad; Boak, Jennifer; Darlington, Andrew; Kaszonyi, Kathryn; Sloan, Stephen, B; Wood, Deborah; Jundi, Mayar; Ostrander, Ann; Khosla, Sandeep; Lukka, Sudha; Williams, Marcus, L; Michel, Kimberly; Artis, Andre; Armstrong, Kimberly; Kondo, Nicholas; Kostedt, Gretchen; Galtes, Israel; Diaz, Yasnhai; Martinez, Luis; Penafiel, Beatriz; Cardona, Jose, F; Juarez, Abril; Abdullah, Shuaib; Atwell, Amy; Sharf, Albert, J; Cortes, Leonardo; Bhagwat, Ravi; Winterrowd, Donna; Michael Donath, Elie; Ycaza, Maria; Jones, Alonzo; Gillespie, Eve; Keane-Richmond, Pat; Becker, Richard; Mardis, Rachel; Fail, Peter, S; Parfait, Vicky; Ayalloore, Siby; Rideaux, Tessie; May, Wade; Zannini, Julie; Chugh, Atul, R; Alford, Stephanie; Alhaddad, Mohsin; Holman, Lani; Strader, Russell, J; Gneiting, Alicia; Wells, Terry; Smith, Jessica; Young, Vernon; Buchanan, Cynthia; K Singla, Ish; Roth, Justin; Ooi, Henry; Diedrich, Laura; Colfer, Harry, T; Antonishen, Denise; Romero Zarante, Angela; Zambrano, Yenisca; Hominal, Miguel, Angel; Suarez, Martin; Vottero, Ezequiel, Hector; Lopez, Marcia; Montaña, Oscar; Cendali, Gloria; Vico, Marisa; Giozzi, Erica; Aizenberg, Diego; Coussio, Santiago; Arakaki, Diego; Gelersztein, Miriam; Stibilj, Kathryn; Colquhoun, David, Martin; Macdonald, Gemma; Atherton, John; Lilwall, Lydia; Thomas, Simeoni; Healy, Denise; Beer, Natalya; Rausch, Viktoria; Schober, Andreas; Leitgeb, Maria-Christine; Koehler, Cordula; Auer, Johann; Rossmaier, Manuela; Mirna, Moritz; Saraiva, Jose; Vicente, Carla Cristina; Schwartzmann, Pedro; Ilana, Gabriela; Freitas, Aguinaldo; Costa, Sandra; Moura, Lidia; de Liz, Fernanda; Mourilhe Rocha, Ricardo; Coelho, Roberta; Marcondes-Braga, Fabiana; Antunes, Talita; Simoes, Marcus; Silva, Veronica; Souza, Joao; Freire, Grazielle; Silveira, Fábio; Galvão, Tamyres; Manenti, Euler; Silva, Carollainy; Bourgeois, Ronald, Leonard; Huynh, Thao, Thanh; Hartleib, Michael; Otis, Rebecca; Armstrong, Samantha; Zakria, Lubna; Hayami, Doug; Keller, Deborah; Schaffer, Stephen Allan; Pesant, Yves; Sardin-Laframboise, Yanick; Leblanc, Nathalie; Khaykin, Yaariv; Nemtean, Debbie; Moe, Gordon; Bujold, Amelie; Howlett, Jonathan; Sasikumar, Anusha; Swiggum, Elizabeth; Lounsbury, Noreen; Fortier, Carl; Verma, Subodh; Chen, Debbie; Figueroa, Pamela; Maluenda, Gabriel; Vergara, Maria; Prieto, Juan; Morales, Luis; Zapata, Jessica; Appiani, Franco; del Rio, Tatiana; Mellado, Sergio; Alvarez, Claudia; Cruz, German; Mino, Sebastian; Palma Carvajal, Juan Carlos; Olguin, Veronica; Bourke, Paz; Toledo Grell, Maribel; Marin, Hugo; Rios, Sebastian; Novajas, Manuel; Carcamo Medina, Macarena; Zhou, Jingmin; Lu, Mingfeng; Jiang, Yihan; Kang, Yuhong; Jiang, Luping; Zhong, Yuxin; Jin, Shanshan; Dong, Jianzeng; Wang, Jiajia; Peng, Jianqiang; Peng, Xiaomei; Hou, Aijie; Dai, Wenjuan; Liu, Miaoxia; Chen, Jinxia; Wang, Yutao; Ren, Peiyan; Zhang, Xiying; Chen, Maohua; Lu, Yu; Teng, Xiaoli; Wang, Jiahong; Yan, Xuyao; Gao, Yue; Qiao, Ping; Han, Mizozhu; Liu, Mingya; Wu, Shaorong; Li, Ruihao; Liang, Qian; Ni, Zhengzheng; Ma, Qilin; Li, Ting; Cong, Hongliang; Zhu, Chuangting; Li, Guangping; Liu, Lin; Li, Weimin; Jing, Junsheng; Zhang, Qing; Tang, Jia; Zhao, Cuimei; Ting, Liao; Hu, Xiaosheng; Fang, Yao; Yin, Yuehui; Liu, Xuejun; Jiang, Jun; Zhang, Mengqing; Luo, Yuanyuan; Wang, Siqi; Zhang, Ping; Zhang, Peng; Wu, Yanqing; Wei, Wenting; Pang, Xiaohua; Xia, Yanqiong; Lv, Chenyu; Fang, Zhihua; Du, Qiaochu; Yang, Ping; Liu, Xuejiao; Yuan, Wei; Huang, Kai; Xiang, Danli; Ma, Likun; Liu, Jinxiu; Garcés Restrepo, Claudia; Accini, Jose; Conrado Ortega, Yineth; Caceres, Aleydy; Cadena, Alberto; Martinez, Jessica; Moncada Corredor, Miguel; Florez, Leisa; Arana, Camilo; Diaz Villegas, Lizzette; Molina de Salazar, Dora; Valencia, Maria; Carvajal, Juan; Delgado, Paola; Echeverria, Luis; Bueno Diaz, Karen; Gomez-Mesa, Juan; Trujillo, Laura; Echeverry, Eduardo; Escruceria, Adriana; Reyes Dia, Melissa; Cervantes Hurtado, Adriana; Busak, Ladislav; Pokorna, Blanka; Kuprova, Anna; Brindova, Jana; Miklik, Roman; Musilova, Veronika; Radvan, Martin; Machova, Renata; Belohlavek, Jan; Zavadilova, Petra; Monhart, Zdenek; Bouzkova, Lenka; Drasnar, Tomas; Fald, Matej; Bolvanska, Nora; Packova, Helena; Krejci, Jan; Roche, Jana; Hove, Jens; Ring, Lotte; Lindhardt, Morten; Bang-Hansen, Therese; Madsen, Kristian; Hummelshoej, Joan; Hindsgaul, Linda; Schou, Morten; Madsen, Jette; Nielsen, Søren; Jakobsen, Emilie; Leth, Marianne; Kober, Lars; Eriksen, Elsebet; Eske Bruun, Niels; Kragh, Winnie; Bronnum-Schou, Jens; Hadsund, Pia; Vadmann, Henrik; Nielsen, Annette; Rosolin, Nathalie; Armangau, Pauline; Ferrari, Emile; Belkacem, Nassima; Aludaat, Cadi; Balaya-Gouraya, Line; Berthelot, Emmanuelle; Pezzi, Agnes; Tachot, Emilie; Dutoiu, Teodora; Derien, Anne-Sophie; Boiffard, Emmanuel; Prunier, Philippe; Picard, Francois; Moumni, Manel; Isnard, Richard; Tabdjoun, Ghoulem; Mewton, Nathan; Barry, Bianca; Geissler, Arne; Schumacher, Jeanette; Schwimmbeck, Peter; Dimitroulis, Dimitrios; Simons, Judith; Sinning, Jan-Malte; Müller, Julia; Duersch, Martin; Leyh, Daniela; Wied, Elisa; Overhoff, Ulrich; Lindemann, Hannes; von Hertell, Ines; Rieker, Werner; Anacker, Jelena; Ebelt, Henning; Goebel, Ute; Jabs, Alexander; Kirchenwitz, Stephanie; Mahnkopf, Christian; Hahn, Mario; Bergmann, Martin; Bosredon, Cecile; Brudzinski, Mirko; Steinbruegger, Katja; Linke, Axel; Eck, Kerstin; Gonzalo de Juan, Maria; Schadow, Kerstin; Schaefer, Nicole; Frey, Norbert; Schafer, Benjamin; Markakis, Alexandros; Eberhard, Katrin; Karmpalioti, Maria; Kesoglou, Vaggelitsa-Eirini; Tsioufis, Konstantinos; Gkartzonikas, Ilias; Patsilinakos, Sotirios; Karagogou, Pinelopi; Naka, Aikaterini; Nikolopoulos, Petros; Skoularigkis, Ioannis; Ereliadou, Foteini; Filipatos, Gerasimos; Lathridou, Paraskevi; Ninios, Vlasios; Androutsou, Evangelia; Moutafi, Vasiliki; Briasoulis, Alexandros; Mandila, Christin; Tsougos, Elias; Karavidas, Apostolos; Aguilar Schinini, Mayra; Arango Benecke, Juan, Luis; Ramírez Ávila, Andrea Lucia; Montenegro Valdovinos, Pablo, Carlos; Ting Wang, Xue; Rodas Diaz, Marco; San Lui Ho, Venus; Hai, Siu Han Jojo; Lee, Kar Wai; Fan, Katherine Yue Yan; Nagy, Zsolt; Chan, Ngai-Yin; Rozsa Toth, Karolyne; Kósa-Hóbor, Laura; Bartha, Barna; Bencze, Gabriella; Papp, Andras; Kiss, Gabor; Zilahi, Zsolt; Kovacs, Szilvia; Kovacs, Istvan; Levang, Szilvia; Toth, Tunde; Nagy, Monika; Habon, Tamas; Kónyi, Réka; Takacs, Janos; Hadi, Nora; Konyi, Attila; Spandli, Katalin; Benczur, Bela; Szabone Nagy, Maria; Literati-Nagy, Botond; Kormanyos, Arpad; Nagy, Andras; Ibolya Mihaly, Gyongyver; Sepp, Robert; Kalapos, Anita; Mayene Abalos, Jan; Thury, Attila; Nabwani, Neda; Paor, Galit; Biener, Meital; Caspi, Oren; Yedid Am, Shiree; Elber, Jenny; Mohsen, Jameel; Barhum, Dema; Swisa, Sapir; Zwas, Donna; Eizenberg, Nava; Goldman, Alexander; Fardman, Alexander; Punzo, Noemi; Mattavelli, Irene; Assoni, Luca; Maffi, Marta; Gallelli, Ilaria; Algeri, Michela; Borghi, Claudio; Famiani, Roberta; Maloberti, Alessandro; Carugo, Stefano; Vannuccini, Francesca; Scapicchi, Caterina; Palazzuoli, Alberto; Cuccuru, Giuditta; Ambrosio, Giuseppe; d'Alessandro, Francesca; de Ferrari, Gaetano; Suhaimi, Manhaiyun; Badagliacca, Roberto; Mohd Bukhari, Fatma Diyana; Alia, Nur; Siti, Khairani; Abidin, Zainal; Tiew, Neoh Poh; Raja, Shariff; Faridz Shariff, Ezman; Mamat, Zalida; Syukur Abdullah, Abd; Wong, Mabelle; Isa, W; Yus Haniff, W; Suhaili Mamat, Nurul; Liew, Houng Bang; Wazi Ramli, Ahmad; Aguilar Sanchez, Ma.; Mendez Machado, Gustavo, Francisco; Guzman Solorzano, Hannah; Arenas León, José; Arias Mendoza, Maria; Flores Pruneda, Rosa; Castro Zarate, Carlos; Bazzoni Ruiz, Alberto; Ramos Ruiz, Ana Rosa; Perez Rios, Jesus; de la Vega, Lucia; Segura Gonzalez, Armando; Mendez, Wendy; Gandoy Vazquez, William; Garcia Gonzalez, Luz Belen; Peralta Rosado, Hilda; Maytorena, Maria; Varela Varela, Alberto; Vazquez, Paul; Goiz, Nazareth; Lopez, Claudia; Fajardo Campos, Pedro; del Muro Munoz, Sergio; Illescas Diaz, Jesus; Medina Reyes, America; Garcia, Ricardo; Cuevas, Araceli; Salazar Lopez, Hector; García Briones, Ana; Matadamas, Norberto; Barcenas, Edgar; Vargas, Castelán; Astorga Rivas, Marcos; Bayram Llamas, Edmundo; Olguin Ortiz, Felipe; Payro, Gerardo; González, Geraldine; Zambrano Ruiz, Eduardo; Rodriguez Cal y Mayor, Arianna; Ricalde, Alejandro; Ramirez Mendoza, Marcelo; Jaques, Sharon; Pemberton, James Pemberton; Dhakshinamurthy, Vijay; Duckworth, Jamie; Kistanna, Danica; Turaga, Mansi; Benatar, Jocelyne; Rodriguez, L. Jeanneth; Rodriguez Escudero, Aldo Edwin; Medina Palomino, Felix; Ariza Villanueva, Carola; Cabrera, Jose; Zena, J.; del Rosario, Norma; Godoy Palomino, Armando, Lionel; Garcia, Maria; Correa, Roger; Castillo, Leonila; Berrospi, Percy; Gil Rescavarren, Maria; Cardoza Anton, Luisa; Chromczak, Bozena; Camacho Cosavalente, Luis; Idzikowska, Paulina; Wilczynska, Joanna; Skoczylas, Grzegorz; Tunkiewicz, Monika; Pawlowicz, Lidia; Cieszynska, Alina; Zajdel, Wojciech; Cymerman, Krzysztof; Polak, Agnieszka; Augustyn, Marta; Zurakowski, Aleksander; Ryznar-Sicinska, Anna; Witek, Robert; Markiewicz, Natalia; Mazur, Stanislaw; Beme, Anna; Walasek, Pawel; Miklaszewicz, Beata; Matys, Urszula; Gniot, Jacek; Rolirad, Monika; Sudnik, Wanda; Bartoszewska, Dorota; Skonieczny, Grzegorz, Krzysztof; Camacho-Molina, Airleen; Prokopczuk, Janusz; Molina Elicier, Brenda; Toro-Grajales, Ismael; Torres-Rivas, Noemi; Matta Fontanet, Evelyn; Alcocer Rodriguez, Loriany; Figueroa-Torres, Yolanda; Zhernokleev, Andrei; Rodriguez-Ospina, Luis; Volkova, Elena; Ledyaeva, Alla; Bolshakova, Lga; Evtushenko, Oxana; Peregudova, Natalia; Solnyshkov, Sergey; Garina, Irina; Shutemova, Elena; Khaisheva, Larisa; Kraeva, Irina; Koziolova, Natalya; Kizhvatova, Natalia; Kositsyn, Dmitry; Yakovleva, Elena; Kosmacheva, Elena; Dronov, Dmitry; Lukyanov, Yury; Sorokina, Olga; Samodurova, Anna; Isaeva, Elena; Trukshina, Maria; Kovalchuk, Evgeniy; Ustiuzhanin, Nikloai; Sitnikova, Maria; Febriana, Eveline; Zykov, Mikhail; Chua, Xin Tian; Sim, Kheng Leng David; Ang, Kah Min; Fuad, Siti Norashikin Binte; Lin, Weiqin; van der Mescht, Marelize; Huang, Weiliang; Burgess, Lesley; Greyling, Louwra; Ameen Fulat, Muhammad; Makotoko, Ellen, Makoali; Katisi, Deborah; Mosia, Nozibusiso; Mngqibisa, Rosie; van Vuuren, Sonnika; Madavha, Unarine; Mohamed, Zarinah; Nortje, Engela; Rheeder, Paul; Jacovides, Tracy; Arnold, Susan; Stuurman, Chano; Jacovides, Andrew; Faul, Catharina; Coetzee, Kathleen; Mohamed, Zakariyyaa; de Jong, Douwe; Park, Seul Gi; Dawood, Riaz; Lee, Ryeong Gyeong; Kim, Eun; Park, Boram; Chae, Gaeul; Chung, Wook-Jin; You, Miju; Cho, Hyun-Jai; Rodriguez Penas, Diego; Carrasco Ossorio, Catalina; Reyes Dominguez, Antonio; Martinez Jaen, Ruben; Nunez Villota, Julio; Viaplana, Judith; Ferreira, Ignacio; Sicilia Bravo, Isabel; Comin-Colet, Josep; Gonzalez Portilla, Paz; Goirigolzarri Artaza, Josebe; Soler, Cristina; Alvarez Garcia, Jesus; Gastelurrutia, Paloma; Bayes Genis, Antoni; Grille Cancela, Zulaica; Lopez de Sa Areses, Esteban; From, Kristina; Generosa Crespo Leiro, Maria; Haglund, Pernilla; Bergh, Niklas; Broberg, Malin; Szabo-Soderberg, Barna; Eriksson, Kristina; Lindholm, Carl-Johan; Andersson, Carina; Svedberg, Niclas; Tronstad, Isabel; Lonnberg, Ingemar; Södergren, Håkan; Najjar, Emil; Rangman, Birgitta; Lind, Marcus; Chang, Chiao-Wen; Olsson, Ake; Su, Huey-Pyng; Chou, Ping-Ping; Hsieh, I-Chang; Huang, Hui-Ling; Huang, Jin-Long; Lee, Hsiao-Ting; Lin, Tsung-Hsien; Aydin, Akin; Hsia, Chien-Hsun; Kaygusuz, Burcu; Yildirim, Selin; Tak, Bahar; Durhan, Özge; Nalbantgil, Sanem; Sahin, Emel; Sahin, Ebru; Altay, Hakan; Nur Ertunc, Fatma; Onrat, Ersel; Celik Eminoglu, Gizem; Altin, Cihan; Mizrak, Esmanur; Akbulut, Bulut; Baris Kaya, Ergun; Aslan, Ezgi; Barman, Hasan; Akin, Berna; Venugopal, Vineet; Volchyk, Iulia; Duythuc To, Thomas; Chendey, Taras; Pavelko, Mishka; Stets, Roman; Beregova, Olena; Rishko, Mykola; Pysanko, Oksana; Yagensky, Andriy; Lutai, Yaroslav; Rudenko, Leonid; Rudya, Ganna; Reshotko, Dmytro; Yurkiv, Andriy; Parkhomenko, Oleksandr; Gliebova, Oksana; Mishchenko, Larysa; Schyhypak, Diana; Levchenko, Olena; Havryliuk, Halyna; Prokhorov, Oleksandr; Bilonko, Oksana; Dzyba, Alla; Myshanych, Halyna; Radchenko, Olha; Shevchuk, Sergii; Danyliuk, Andrii; Vyshnyvetskyy, Ivan; Danko, Tetiana; Tseluyko, Vira; Petrovskyy, Taras; Klantsa, Andrii; Sovtus, Volodymyra; Kulyk, Anna; Shandra, Tetiana; Petrovskyy, Roman; Romanova, Elena; Vakaliuk, Igor; Babichev, Denys; Zhurba, Svitlana; Krotenko, Ganna; Kumpan, Nataliia; Rudyk, Iurii; Trubina, Svitlana; Yildirimturk, Ozlem; Elphick, Sandra; Genc, Ahmet; Florou, Alexandra; Fuat, Ahmet; Adrego, Rita; Barr, Craig, Scott; Lyons, Sinead; Broadhead, Sarah; Anderson, Lisa; Brown, Joanna; Kinnin, Michelle; Cassidy, Christopher; Galera, Francis; Moriarty, Andrew; Panicker, Abeesh; Mordi, Ify; Mellish, Lisa; Saxena, Manish; Crawford, Susan; Banerjee, Prithwish; Harper, Rosemary; Dewhurst, Matthew; Jones, Deborah; Varma, Madhusudhan; Jones, Ben; Ibrahim, Bassem; Cutts, Rebecca; Wong, Aaron; Doughty, Angela; Jaumdally, Rumi; Regan, Susan; Moore, Patrick; Wilson, David; Donnelly, Patrick; Gutierrez, Haydee; Mccartney Morales, Phillippa; Allina, Jorge; Ariani, Mehrdad; Hamal, Sajad; Youssef, Rasha; Ramirez, Maite; Bernard, David; Budoff, Matthew; Clopp, Kelli; Wyatt, Jaime; Lambert, Stephanie; Reno, Marie; Isiguzo, Obinna; Hroncich, Rose; Forbus, Sabrina; Thornton, Kevin; Dubois, Crystal; Foley, Brian; Maschenik, Heather; Gangasani, Ashish; Vasallo, Moravia; Dirks, Anne; Sogade, Felix; Stamschror, Lauren; Vasallo, Javier; Hughes, Leigha; Ewald, Gregory, Alan; Khalil, Mohamed; Ashchi, Majdi; Blubaugh, Heather; Bui, Hahn; Muro, Rafael; Doran, Jesse; Abu-Saif, Abeer; Bajornas, Jennifer; Ramos, Marisol; Hariri, Imad; Phillips, Alicia; Qureshi, Ataul; Schulte, Jill; Singh, Narendra; Phillips, Andrea; Lust, Malcolm; Vierecke, Juliane; Mckercher, Margie; Killian, Jacqueline; Smith, Victoria; Lloret, Ramon; Iskandarani, Rema; Dib, Nabil; Culver, Breanna; Muhammad, Ali; Michelis, Katherine; Bitar, Fahed; King, Amy; Chandra, Lokesh; Jackson, Richard; Rao, Vijay; Jenkins, Hailey; Hotchkiss, David; Abidov, Yulia; Quebedeaux, Ariel; Janik, Matthew; Hayes-Jones, Sharyce; Osmulski, Teresa; Fiallo, Natalie; Gilder, Emily; Reynolds, Amanda; Williams, Ashley; Surber, Joseph; Howarter, April; Napoli, Mark; Edmond, Robert; Solomon, Alison; Sparrow, Christopher; Assefa, Mihret; Gupta, Divya; Scott, Nicole; Hamroff, Glenn; Tirumanisetti, Sirisha; Dharma, Chrisette; Roberts, Shelli; Herzog, William; Zachary, Lynett; Isseh, Iyad; Moore, Loren; Daniels, Christopher; Runquist, Lars; Strugatsky, Svetlana; Tabbal, Ghiyath; Vekariya, Nehal; Stevens, Ramona; Mody, Freny; Alajlouni, Ibraheem; Arora, Pankaj; Osmond, Peter; El Shahawy, Mahfouz; Evans, Yasmire; Mikdadi, Ghiath; Kallas, Nadine; Izzo, Joseph; Adeusi, Iluyomade; Lala-Trindade, Anu; English, Lisa; Bostick, Brian; Piskun, Anastasiia; Cornell, Alexandra; Lamont, Katie; Zilli, Martina; Christopher, Lydia; Marcondes, Fabiana; Zieroth, Shelley; Ducharme, Anique; Ge, Junbo; Gómez, Juan Esteban; Stoerk, Stefan; Filippatos, Gerasimos; Montenegro, Pablo; Lee, Alex; Mcdonald, Ken; Metra, Marco; Abidin, Imran; Medina, Felix, Alvaro; Sliwa, Karen; Leiro, Marisa; Cavusoglu, Yüksel; Greenberg, Barry; Cook, Tom, D; Maggioni, Aldo; Wilcox, Jane, E; Costanzo, Maria Rosa; Gutierrez, Jorge; Kittipibul, Mark; Kolls, Bradley; Kong, David; Lerman, Joseph; Matthews, Robert; Mcgarrah, Robert; Mehta, Rajendra; Rymer, Jennifer; Sasannejad, Cina |
| Contributors: |
Défaillance Cardiovasculaire Aiguë et Chronique (DCAC); Centre Hospitalier Régional Universitaire de Nancy (CHRU Nancy)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lorraine (UL); Centre d'investigation clinique plurithématique Pierre Drouin Nancy (CIC-P); Centre d'investigation clinique Nancy (CIC); Centre Hospitalier Régional Universitaire de Nancy (CHRU Nancy)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lorraine (UL)-Centre Hospitalier Régional Universitaire de Nancy (CHRU Nancy)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lorraine (UL); Cardiovascular and Renal Clinical Trialists Vandoeuvre-les-Nancy (INI-CRCT); Institut Lorrain du Coeur et des Vaisseaux Louis Mathieu Nancy; French-Clinical Research Infrastructure Network - F-CRIN Paris (Cardiovascular & Renal Clinical Trialists - CRCT); Inova Heart and Vascular Institute Falls Church, VA, USA (IHVI); Baylor Scott and White Research Institute Dallas, TX, USA; University of Southern Mississippi (USM); Merck Sharp and Dohme (Merck & Co. Inc); Université de Caroline du Nord à Chapel Hill = University of North Carolina Chapel Hill (UNC-Chapel Hill); University of North Carolina System (UNC); University of Colorado Colorado Springs; Bayer, Research & Development, Pharmaceuticals; Bayer HealthCare Pharmaceuticals, Inc. Basel, Switzerland (BHCP); Pharmaceutical Sciences, Merck & Co. Inc.; Merck Research laboratories; Merck Sharp and Dohme (Merck & Co. Inc)-Merck Sharp and Dohme (Merck & Co. Inc); University of Alberta; Duke Clinical Research Institute; National Heart Centre Singapore (NHCS); Duke-National University of Singapore Graduate Medical School; Stanford School of Medicine Stanford; Stanford Medicine; Stanford University-Stanford University; Vanderbilt University Medical Center Nashville; Vanderbilt University Nashville; Duke University Medical Center; Wrocław Medical University; Mayo Clinic Rochester; Istituto di Ricovero e Cura a Carattere Scientifico San Raffaele Roma (IRCCS San Raffaele Pisana); San Raffaele Open University of Rome; Universidad Pontificia Bolivariana (UPB); Universidad de Antioquia = University of Antioquia Medellín, Colombia; Hospital Papa Giovanni XXIII (Hosp P Giovanni XXIII); Università degli Studi di Milano-Bicocca = University of Milano-Bicocca (UNIMIB); Technische Universität Munchen = Technical University Munich = Université Technique de Munich (TUM); Bayer AG Germany; Tufts Medical Center Boston; Bayer U.S., LLC, Whippany, NJ.; University Medical Center Groningen Groningen (UMCG); BAIF Institute for Sustainable Livelihoods and Development, Gujarat, India.; Charité - UniversitätsMedizin = Berlin University Medicine; German Center for Cardiovascular Research (DZHK); Berlin Institute of Health (BIH); German Heart Center Berlin; Merck Research Laboratories; Institut photonique d'analyse non-destructive européen des matériaux anciens (IPANEMA); Muséum national d'Histoire naturelle (MNHN)-Université de Versailles Saint-Quentin-en-Yvelines (UVSQ)-Centre National de la Recherche Scientifique (CNRS)-Ministère de la Culture (MC); Excelia Group; Transitions Energétiques et Environnementales (TREE); Université de Pau et des Pays de l'Adour (UPPA)-Centre National de la Recherche Scientifique (CNRS); Centre National de la Recherche Scientifique (CNRS) |
| Source: |
ISSN: 0140-6736. |
| Publisher Information: |
CCSD; Elsevier |
| Publication Year: |
2025 |
| Collection: |
Université de Versailles Saint-Quentin-en-Yvelines: HAL-UVSQ |
| Subject Terms: |
SQ Innovation; InterShunt; Innoventric; FIRE1; Cordio Medical; Axon Therapies; Alleviant Medical; and Adonis; Vifor Pharma; Ultromics; Tricog Health; Tenex Therapeutics; Orchestra BioMed; Sequana Medical; Secretome Therapeutics; scPharmaceuticals; Sanofi; Salamandra; Roche; Renibus Therapeutics; Regeneron Pharmaceuticals; Prolaio; PharmaIN; and Viatris; bureaus; or educational events from Bayer; Boehringer Ingelheim; and consulting fees from Abbott Laboratories; and V-Wave. RJM has received research support and honoraria from Bayer and Merck Sharp &; amp |
| Description: |
International audience ; Background Following completion of the VICTORIA trial, vericiguat was approved for the treatment of worsening heart failure with reduced ejection fraction (HFrEF) and received a class IIb recommendation in European and North American guidelines. The subsequent VICTOR trial evaluated the use of vericiguat in patients with HFrEF and no recent worsening. We aimed to assess the effect of vericiguat on clinical endpoints through pooled analyses of patientlevel data from the VICTORIA and VICTOR trials. Methods This prespecified, pooled individual participant-level analysis was conducted on data from two trials: VICTORIA, which was active from Sept 25, 2016, to Sept 2, 2019 in 42 countries, and VICTOR, which was active from Nov 2, 2021, to Feb 5, 2025 in 36 countries. The VICTORIA trial enrolled adult (aged ≥18 years) participants with HFrEF with recent worsening (defined as either hospitalisation for heart failure within the previous 6 months or outpatient use of intravenous diuretics within the previous 3 months) and increased NT-proBNP concentrations; the VICTOR trial had similar eligibility criteria but participants had no recent worsening of heart failure. Participants in both trials received contemporary background guideline-directed heart failure therapy as appropriate. The primary endpoint was a composite endpoint of cardiovascular death or hospitalisation for heart failure (also assessed individually). This study is registered with PROSPERO, CRD420251065636. Findings Data from 11 155 patients (5050 in the VICTORIA trial and 6105 in the VICTOR trial) were included in the pooled analysis. The primary endpoint of cardiovascular death or hospitalisation for heart failure occurred in 1446 (25•9%) of 5579 patients in the vericiguat group and 1556 (27•9%) of 5576 patients in the placebo group (hazard ratio [HR] 0•91 [95% CI 0•85-0•98]; p=0•0088), with similar reductions in its individual components of cardiovascular death (0•89 [0•80-0•98]; p=0•020) and hospitalisation for heart failure (0•92 ... |
| Document Type: |
article in journal/newspaper |
| Language: |
English |
| Relation: |
info:eu-repo/semantics/altIdentifier/pmid/40897188; PUBMED: 40897188 |
| DOI: |
10.1016/S0140-6736(25)01682-4 |
| Availability: |
https://hal.univ-lorraine.fr/hal-05237757; https://hal.univ-lorraine.fr/hal-05237757v1/document; https://hal.univ-lorraine.fr/hal-05237757v1/file/1-s2.0-S0140673625016824-main.pdf; https://doi.org/10.1016/S0140-6736(25)01682-4 |
| Rights: |
https://creativecommons.org/licenses/by/4.0/ ; info:eu-repo/semantics/OpenAccess |
| Accession Number: |
edsbas.CADA6314 |
| Database: |
BASE |