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Iatrogenic ocular surface diseases occurring during and/or after different treatments for ocular tumours

Title: Iatrogenic ocular surface diseases occurring during and/or after different treatments for ocular tumours
Authors: Giannaccare G.; Bernabei F.; Angi M.; Pellegrini M.; Maestri A.; Romano V.; Scorcia V.; Rothschild P. -R.
Contributors: Giannaccare, G.; Bernabei, F.; Angi, M.; Pellegrini, M.; Maestri, A.; Romano, V.; Scorcia, V.; Rothschild, P. -R.
Publication Year: 2021
Collection: Università degli Studi di Ferrara: CINECA IRIS
Subject Terms: Anti-cancer agent; Choroidal melanoma; Complication; Dry eye; Ocular surface; Ocular surface squamous neoplasia; Ocular tumour; Radiotherapy; Uveal melanoma
Description: The ocular surface represents a finely regulated system that allows the protection of the eye. It is particularly susceptible to different treatments for intraocular tumours, such as uveal melanoma and conjunctival cancers. Traditionally, the management of ocular tumours depends on the characteristics of the lesion, and is based on a combination of selective surgery, topical chemotherapy, and/or radiotherapy delivered through different mechanisms (e.g., charged-particle radiotherapy or brachy-therapy). Possible complications involving the ocular surface range from transient dry eye disease or keratitis up to corneal melting and perforation, which in any case deserve careful evaluation for the risk of permanent sigh-threatening complications. Clinicians involved in the management of these patients must be aware of this risk, in order to reach an early diagnosis and promptly set up an adequate treatment. The present review of the literature will summarize acute and chronic complications affecting the ocular surface following different therapies for the treatment of ocular tumours.
Document Type: article in journal/newspaper
File Description: STAMPA
Language: English
Relation: info:eu-repo/semantics/altIdentifier/pmid/33923737; info:eu-repo/semantics/altIdentifier/wos/WOS:000644011000001; volume:13; issue:8; firstpage:1933-1; lastpage:1933-17; numberofpages:17; journal:CANCERS; https://hdl.handle.net/11392/2470068
DOI: 10.3390/cancers13081933
Availability: https://hdl.handle.net/11392/2470068; https://doi.org/10.3390/cancers13081933; https://www.mdpi.com/2072-6694/13/8/1933
Rights: info:eu-repo/semantics/openAccess ; license:Creative commons ; license uri:http://creativecommons.org/licenses/by/4.0/
Accession Number: edsbas.CC3DA49D
Database: BASE