Mechanisms of environmental chemicals that enable the cancer hallmark of evasion of growth suppression
| Title: | Mechanisms of environmental chemicals that enable the cancer hallmark of evasion of growth suppression |
|---|---|
| Authors: | Nahta R; Al-Mulla F; Al-Temaimi R; Amedei A; Andrade-Vieira R; Bay S; Brown DG; Calaf GM; Castellino RC; Cohen-Solal KA; Colacci A; Cruickshanks N; Dent P; Di Fiore R; Forte S; Goldberg GS; Hamid RA; Krishnan H; Laird DW; Lasfar A; Marignani PA; Memeo L; Mondello C; Naus CC; Ponce-Cusi R; Raju J; Roy D; Roy R; Ryan EP; Salem HK; Ivana Scovassi A; Singh N; Vaccari M; Vento R; Vondracek J; Wade M; Woodrick J; Bisson WH. |
| Source: | Carcinogenesis (N.Y., Print) 36 (2015): S2–S18. doi:10.1093/carcin/bgv028 ; info:cnr-pdr/source/autori:Nahta R, Al-Mulla F, Al-Temaimi R, Amedei A, Andrade-Vieira R, Bay S, Brown DG, Calaf GM, Castellino RC, Cohen-Solal KA, Colacci A, Cruickshanks N, Dent P, Di Fiore R, Forte S, Goldberg GS, Hamid RA, Krishnan H, Laird DW, Lasfar A, Marignani PA, Memeo L, Mondello C, Naus CC, Ponce-Cusi R, Raju J, Roy D, Roy R, Ryan EP, Salem HK, Ivana Scovassi A, Singh N, Vaccari M, Vento R, Vondracek J, Wade M, Woodrick J, Bisson WH./titolo:Mechanisms of environmental chemicals that enable the cancer hallmark of evasion of growth suppression/doi:10.1093carcinbgv028/rivista:Carcinogenesis .... |
| Publisher Information: | Oxford University Press, Oxford , Regno Unito |
| Publication Year: | 2015 |
| Collection: | PUMAlab (ISTI CNR - Consiglio Nazionale delle Ricerche / National Research Council) |
| Subject Terms: | environmental chemical; cancer; cell growth suppression |
| Description: | As part of the Halifax Project, this review brings attention to the potential effects of environmental chemicals on important molecular and cellular regulators of the cancer hallmark of evading growth suppression. Specifically, we review the mechanisms by which cancer cells escape the growth-inhibitory signals of p53, retinoblastoma protein, transforming growth factor-beta, gap junctions and contact inhibition. We discuss the effects of selected environmental chemicals on these mechanisms of growth inhibition and cross-reference the effects of these chemicals in other classical cancer hallmarks. |
| Document Type: | article in journal/newspaper |
| Language: | English |
| Relation: | info:cnr-pdr/author/matricola:19184/SCOVASSI/ANNA; info:cnr-pdr/author/matricola:39138/MONDELLO/CHIARA; http://www.cnr.it/prodotto/i/333247; https://publications.cnr.it/doc/333247; https://dx.doi.org/10.1093/carcin/bgv028; info:doi:10.1093/carcin/bgv028 |
| DOI: | 10.1093/carcin/bgv028 |
| Availability: | http://www.cnr.it/prodotto/i/333247; https://publications.cnr.it/doc/333247; https://doi.org/10.1093/carcin/bgv028; http://www.scopus.com/inward/record.url?eid=2-s2.0-84937697813&partnerID=q2rCbXpz |
| Rights: | info:eu-repo/semantics/restrictedAccess |
| Accession Number: | edsbas.CD03F1EA |
| Database: | BASE |