Impact of nonoptimal intakes of saturated, polyunsaturated, and trans fat on global burdens of coronary heart disease
| Title: | Impact of nonoptimal intakes of saturated, polyunsaturated, and trans fat on global burdens of coronary heart disease |
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| Authors: | Wang, Qianyi; Afshin, Ashkan; Yakoob, Mohammad Yawar; Singh, Gitanjali M.; Rehm, Colin D.; Khatibzadeh, Shahab; Micha, Renata; Shi, Peilin; Mozaffarian, Dariush; Ezzati, Majid; Fahimi, Saman; Wirojratana, Pattra; Powles, John; Elmadfa, Ibrahim; Rao, Mayuree; Alpert, Warren; Lim, Stephen S.; Engell, Rebecca E.; Andrews, Kathryn G.; Abbott, Pamela A.; Abdollahi, Morteza; Abeyá Gilardon, Enrique O.; Ahsan, Habibul; Al Nsour, Mohannad Abed Alfattah; Al-Hooti, Suad N.; Arambepola, Carukshi; Fernando, Dulitha N.; Barennes, Hubert; Barquera, Simon; Baylin, Ana; Becker, Wulf; Bjerregaard, Peter; Bourne, Lesley T.; Capanzana, Mario V.; Castetbon, Katia; Chang, Hsing Yi; Chen, Yu; Cowan, Melanie J.; Riley, Leanne M.; De Henauw, Stefaan; Ding, Eric L.; Duante, Charmaine A.; Duran, Pablo; Barbieri, Heléne Enghardt; Farzadfar, Farshad; Hadziomeragic, Aida Filipovic; Fisberg, Regina M.; Forsyth, Simon; Garriguet, Didier; Gaspoz, Jean Michel; Gauci, Dorothy; Calleja, Neville; Ginnela, Brahmam N V; Guessous, Idris; Gulliford, Martin C.; Hadden, Wilbur; Haerpfer, Christian; Hoffman, Daniel J.; Houshiar-Rad, Anahita; Huybrechts, Inge; Hwalla, Nahla C.; Ibrahim, Hajah Masni; Inoue, Manami; Jackson, Maria D.; Johansson, Lars; Keinan-Boker, Lital; Kim, Cho il; Koksal, Eda; Lee, Hae Jeung; Li, Yanping; Lipoeto, Nur Indrawaty; Ma, Guansheng; Mangialavori, Guadalupe L.; Matsumura, Yasuhiro; McGarvey, Stephen T.; Fen, Chan Mei; Monge-Rojas, Rafael A.; Musaiger, Abdulrahman Obaid; Nagalla, Balakrishna; Naska, Androniki; Ocke, Marga C.; Oltarzewski, Maciej; Szponar, Lucjan; Orfanos, Philippos; Ovaskainen, Marja Leena; Tapanainen, Heli; Pan, Wen Harn; Panagiotakos, Demosthenes B.; Pekcan, Gulden Ayla; Petrova, Stefka; Piaseu, Noppawan; Pitsavos, Christos; Posada, Luz Gladys; Sánchez-Romero, Luz Maria; Selamat, Rusidah B T; Sharma, Sangita; Sibai, Abla Mehio; Sichieri, Rosely; Simmala, Chansimaly; Steingrimsdottir, Laufey; Swan, Gillian; Sygnowska, Elzbieta Halina; Templeton, Robert; Thanopoulou, Anastasia; Thorgeirsdóttir, Holmfridur; Thorsdottir, Inga; Trichopoulou, Antonia; Tsugane, Shoichiro; Turrini, Aida; Vaask, Sirje; van Oosterhout, Coline; Veerman, J. Lennert; Verena, Nowak; Waskiewicz, Anna; Zaghloul, Sahar; Zajkás, Gábor |
| Source: | Wang, Q, Afshin, A, Yakoob, M Y, Singh, G M, Rehm, C D, Khatibzadeh, S, Micha, R, Shi, P, Mozaffarian, D, Ezzati, M, Fahimi, S, Wirojratana, P, Powles, J, Elmadfa, I, Rao, M, Alpert, W, Lim, S S, Engell, R E, Andrews, K G, Abbott, P A, Abdollahi, M, Abeyá Gilardon, E O, Ahsan, H, Al Nsour, M A A, Al-Hooti, S N, Arambepola, C, Fernando, D N, Barennes, H, Barquera, S, Baylin, A, Becker, W, Bjerregaard, P, Bourne, L T, Capanzana, M V, Castetbon, K, Chang, H Y, Chen, Y, Cowan, M J, Riley, L M, De Henauw, .... |
| Publication Year: | 2016 |
| Collection: | King's College, London: Research Portal |
| Subject Terms: | Cardiovascular disease; Coronary heart disease; Dietary fat; Saturated fat; Trans fat; X-6 polyunsaturated fat |
| Description: | Background: Saturated fat (SFA), x-6 (n-6) polyunsaturated fat (PUFA), and trans fat (TFA) influence risk of coronary heart disease (CHD), but attributable CHD mortalities by country, age, sex, and time are unclear. Methods and Results: National intakes of SFA, n-6 PUFA, and TFA were estimated using a Bayesian hierarchical model based on country-specific dietary surveys; food availability data; and, for TFA, industry reports on fats/oils and packaged foods. Etiologic effects of dietary fats on CHD mortality were derived from meta-analyses of prospective cohorts and CHD mortality rates from the 2010 Global Burden of Diseases study. Absolute and proportional attributable CHD mortality were computed using a comparative risk assessment framework. In 2010, nonoptimal intakes of n-6 PUFA, SFA, and TFA were estimated to result in 711 800 (95% uncertainty interval [UI] 680 700-745 000), 250 900 (95% UI 236 900-265 800), and 537 200 (95% UI 517 600-557 000) CHD deaths per year worldwide, accounting for 10.3% (95% UI 9.9%-10.6%), 3.6%, (95% UI 3.5%-3.6%) and 7.7% (95% UI 7.6%-7.9%) of global CHD mortality. Tropical oil-consuming countries were estimated to have the highest proportional n-6 PUFA- and SFAattributable CHD mortality, whereas Egypt, Pakistan, and Canada were estimated to have the highest proportional TFA-attributable CHD mortality. From 1990 to 2010 globally, the estimated proportional CHD mortality decreased by 9% for insufficient n-6 PUFA and by 21% for higher SFA, whereas it increased by 4% for higher TFA, with the latter driven by increases in low- and middle-income countries. Conclusions: Nonoptimal intakes of n-6 PUFA, TFA, and SFA each contribute to significant estimated CHD mortality, with important heterogeneity across countries that informs nation-specific clinical, public health, and policy priorities. |
| Document Type: | article in journal/newspaper |
| File Description: | application/pdf |
| Language: | English |
| DOI: | 10.1161/JAHA.115.002891 |
| Availability: | https://kclpure.kcl.ac.uk/portal/en/publications/c1159448-c972-4d1c-bfb0-54ecc7c97356; https://doi.org/10.1161/JAHA.115.002891; https://kclpure.kcl.ac.uk/ws/files/61952744/Impact_of_Nonoptimal_Intakes_WANG_Accepted_GOLD_VoR_CCBYNC.pdf; https://www.scopus.com/pages/publications/84998636455 |
| Rights: | info:eu-repo/semantics/openAccess ; http://creativecommons.org/licenses/by-nc/4.0/ |
| Accession Number: | edsbas.CDCC3E9F |
| Database: | BASE |