| Title: |
Common, intermediate and well-documented HLA alleles in world populations:CIWD version 3.0.0 |
| Authors: |
Hurley, Carolyn K.; Kempenich, Jane; Wadsworth, Kim; Sauter, Jürgen; Hofmann, Jan A.; Schefzyk, Daniel; Schmidt, Alexander H.; Galarza, Pablo; Cardozo, Maria B.R.; Dudkiewicz, Malgorzata; Houdova, Lucie; Jindra, Pavel; Sorensen, Betina S.; Jagannathan, Latha; Mathur, Ankit; Linjama, Tiina; Torosian, Tigran; Freudenberger, Rafi; Manolis, Anastasios; Mavrommatis, John; Cereb, Nezih; Manor, Sigal; Shriki, Nira; Sacchi, Nicoletta; Ameen, Reem; Fisher, Raewyn; Dunckley, Heather; Andersen, Irene; Alaskar, Ahmed; Alzahrani, Mohsen; Hajeer, Ali; Jawdat, Dunia; Nicoloso, Grazia; Kupatawintu, Pawinee; Cho, Louise; Kaur, Ashminder; Bengtsson, Mats; Dehn, Jason |
| Source: |
Hurley , C K , Kempenich , J , Wadsworth , K , Sauter , J , Hofmann , J A , Schefzyk , D , Schmidt , A H , Galarza , P , Cardozo , M B R , Dudkiewicz , M , Houdova , L , Jindra , P , Sorensen , B S , Jagannathan , L , Mathur , A , Linjama , T , Torosian , T , Freudenberger , R , Manolis , A , Mavrommatis , J , Cereb , N , Manor , S , Shriki , N , Sacchi .... |
| Publisher Information: |
Uppsala universitet, Klinisk immunologi; Georgetown Univ, Dept Oncol, Washington, DC USA.; Natl Marrow Donor Program, Minneapolis, MN USA.; DKMS, Tubingen, Germany.; Argentine HSC Donors Registry, Buenos Aires, DF, Argentina.; Cent Unrelated Potential Bone Marrow Donor & Cord, Warsaw, Poland.; Univ West Bohemia, New Technol Informat Soc, Plzen, Czech Republic.; Czech Natl Marrow Donors Registry, Plzen, Czech Republic.;Univ Hosp Plzen, Plzen, Czech Republic.; Aarhus Univ Hosp, Danish Stem Cell Donors West, Aarhus, Denmark.; DKMS BMST Fdn India, Bangalore, Karnataka, India.;Bangalore Med Serv Trust, Bangalore, Karnataka, India.; Bangalore Med Serv Trust, Bangalore, Karnataka, India.; Finnish Stem Cell Registry, Helsinki, Finland.; Fundacja DKMS, Warsaw, Poland.; Gift Life Marrow Registry, Boca Raton, FL USA.; HTO, Athens, Greece.; DATRI Blood Stem Cell Donor Registry, Chennai, Tamil Nadu, India.; Israel Ezer Mizion Bone Marrow Donor Registry, Bnei Braq, Israel.; Italian Bone Marrow Donor Registry, Genoa, Italy.; Kuwait Natl Stem Cell Registry, Jabriya, Kuwait.; New Zealand Bone Marrow Donor Registry, Auckland, New Zealand.; New Zealand Blood Serv, Auckland, New Zealand.; Norwegian Bone Marrow Donor Registry, Oslo, Norway.; King Saud bin Abdulaziz Univ Hlth Sci, King Abdullah Int Med Res Ctr, Minist Natl Guard Hlth Affairs, Saudi Stem Cell Donor Registry, Riyadh, Saudi Arabia.; Swiss Blood Stem Cells, Bern, Switzerland.; Thai Natl Stem Cell Donor Registry, Bangkok, Thailand.; Bone Marrow Donor Programme, Singapore, Singapore.; Uppsala Univ, Tobias Registry Swedish Bone Marrow Donors, Uppsala, Sweden.; WILEY |
| Publication Year: |
2020 |
| Subject Terms: |
alleles; ethnic groups; gene frequency; HLA; envir; anthro-se |
| Description: |
A catalog of common, intermediate and well-documented (CIWD) HLA-A, -B, -C, -DRB1, -DRB3, -DRB4, -DRB5, -DQB1 and -DPB1 alleles has been compiled from over 8 million individuals using data from 20 unrelated hematopoietic stem cell volunteer donor registries. Individuals are divided into seven geographic/ancestral/ethnic groups and data are summarized for each group and for the total population. P (two-field) and G group assignments are divided into one of four frequency categories: common (≥1 in 10 000), intermediate (≥1 in 100 000), well-documented (≥5 occurrences) or not-CIWD. Overall 26% of alleles in IPD-IMGT/HLA version 3.31.0 at P group resolution fall into the three CIWD categories. The two-field catalog includes 18% (n = 545) common, 17% (n = 513) intermediate, and 65% (n = 1997) well-documented alleles. Full-field allele frequency data are provided but are limited in value by the variations in resolution used by the registries. A recommended CIWD list is based on the most frequent category in the total or any of the seven geographic/ancestral/ethnic groups. Data are also provided so users can compile a catalog specific to the population groups that they serve. Comparisons are made to three previous CWD reports representing more limited population groups. This catalog, CIWD version 3.0.0, is a step closer to the collection of global HLA frequencies and to a clearer view of HLA diversity in the human population as a whole. |
| Document Type: |
article in journal/newspaper |
| Language: |
English |
| Relation: |
https://pure.au.dk/ws/files/220333787/tan.13811.pdf; https://pure.au.dk/portal/da/publications/common-intermediate-and-welldocumented-hla-alleles-in-world-populations(a582979e-57c0-44f2-83db-e372d27de7c4).html |
| Availability: |
https://pure.au.dk/ws/files/220333787/tan.13811.pdf; https://pure.au.dk/portal/da/publications/common-intermediate-and-welldocumented-hla-alleles-in-world-populations(a582979e-57c0-44f2-83db-e372d27de7c4).html |
| Rights: |
undefined |
| Accession Number: |
edsbas.CE9FE0D |
| Database: |
BASE |