| Title: |
COMPARISON OF TWO DIFFERENT METRONIDAZOLE THERAPY REGIMEN IN INTESTINAL AMEBIOSIS ; İNTESTİNAL AMİBİYOZ'DA METRONİDAZOL TEDAVİSİNİN İKİ FARKLI UYGULAMASININ KARŞILAŞTIRILMASI |
| Authors: |
Karabay, Oğuz; Gödekmerdan, Ahmet; Kaplan, Mustafa; Teker, Bahri; Demirel, Kadri |
| Source: |
Volume: 6, Issue: 3457-460 ; 1300-9818 ; Fırat Tıp Dergisi |
| Publisher Information: |
Fırat University; Fırat Üniversitesi |
| Publication Year: |
2014 |
| Collection: |
DergiPark Akademik (E-Journals) |
| Description: |
Aim:In this study, clinical effectiveness and tolerance to metronidazole treatment carried out in two different regimens were compared. Materials and Methods: Forty-six cases applied to Infectious Disease Out Patient Clinics with dysentery complaints, were included in the study. In the stool samples, E. histolytica trophozoites were determined and no additional infectious agents that might cause diarrhea were present. In the group I. 10 day metronidazole treatment at 3x 750 mg/day dose was administered. In the group II., 5 day metronidazole treatment at 1x2000 mg/day dose were followed. During the study, daily clinical examination and parasitological test were performed for the first 5 day and on the day 14th. Results: In both groups, a complete treatment (0) was obtained, and no difference in terms of effectiveness and side effects were noticed between treatment groups. Two cases from the group I did not complete the treatment regimen for unknown reasons. Compared with the 10 day regimen, treatment for 5 day is cost effective and more convenient. Additionally, no significant difference was noted between two groups. Conclusion: It is deemed advisable that 5 day metronidazole treatment at 1x2000 mg/day dose might be used for treatment of intestinal amebiosis. ; Amaç:İntestinal amibiyoz hastalarında metronidazolün 3X750 mg/gün dozda 10 gün uygulanması ile 1X2000 mg/gün dozda 5 gün uygulanmasının klinik etkinlik ve toleransı yönünden karşılaştırılması amaçlanmıştır. Gereç ve Yöntem: Çalışmamızda dizanteri yakınması ile enfeksiyon hastalıkları polikliniğine başvuran, dışkı örneklerinde E. histolytica trofozoitleri saptanan ve ishale neden olabilecek başka enfeksiyöz etken saptanmayan toplam 46 olgu alındı. Başvurudan itibaren ilk beş gün ve 14. gün tüm hastaların klinik kontrolleri ve parazitolojik incelemeleri yapıldı. Bulgular: Her iki grupta da 0 tedavi sağlanmış, etkinlik ve ilaç yan etkileri açısından bir fark saptanmamıştır. I. grupta iki olgunun tedaviyi tamamlamadığı görülmüştür. Sonuç: Hem daha ekonomik ... |
| Document Type: |
article in journal/newspaper |
| File Description: |
application/pdf |
| Language: |
Turkish |
| Relation: |
https://dergipark.org.tr/tr/download/article-file/72813; https://dergipark.org.tr/tr/pub/firattip/issue/6389/85341 |
| Availability: |
https://dergipark.org.tr/tr/pub/firattip/issue/6389/85341 |
| Accession Number: |
edsbas.CF198903 |
| Database: |
BASE |